Test Price
1,200 AED✅ Home Collection Available
UGT1A1 Gene Polymorphism (TA Repeat) Detection Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance in English to interpret your genetic results.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731. We work with all major UAE insurers.
Core Metrics: Test Price – 1200 AED | Turnaround Time – 7 Working Days | Sample – Peripheral Whole Blood (EDTA)
Test Overview & Methodology
The UGT1A1 gene polymorphism (TA repeat) test analyses the number of TA dinucleotide repeats in the UGT1A1 gene promoter to identify common alleles (e.g., (TA)6, (TA)7) that impact drug metabolism and bilirubin clearance. This advanced PCR-fragment analysis is essential for predicting severe irinotecan toxicity and confirming Gilbert syndrome. Our ISO 15189-aligned protocol delivers precise, reproducible results within 7 working days.
| Feature | DNA Labs UAE – Our Test | Closest Alternative |
|---|---|---|
| Methodology | PCR + Capillary Electrophoresis Fragment Analysis (High-Resolution TA Sizing) | PCR + Agarose Gel Electrophoresis (Low Resolution, Ambiguous Repeats) |
| Turnaround Time | 7 Working Days (Guaranteed) | 14–21 Working Days |
| Price | 1200 AED (Inclusive of VIP Home Collection) | 1500–2000 AED (Lab Visit Only) |
| Accreditation | ISO 9001:2015, DHA Licensed (Facility: 1143) | Not Always Stated |
Physician Insight & Safety Protocols
“Understanding your UGT1A1 genetic profile is a key step in personalizing treatment and avoiding severe adverse drug reactions, especially with irinotecan-based chemotherapy. This test provides clear pharmacogenetic guidance, but it must always be interpreted in the context of your full medical history and current therapy. Never alter or discontinue any medication without your treating physician’s oversight.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Warning
Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
- This test should not be used as a standalone diagnostic in acute liver failure or active hemolysis.
- If you develop sudden jaundice, severe right-upper abdominal pain, confusion, or uncontrolled bleeding, seek emergency care immediately.
- Home collection is not advised for patients with current febrile neutropenia; contact our clinical team first.
Patient FAQ & Clinical Guidance
1. How does the UGT1A1 test predict irinotecan toxicity?
This test determines your UGT1A1 gene TA repeat number to predict risk of irinotecan toxicity and guide safer dosing. Individuals carrying two UGT1A1*28 alleles (7/7 genotype) have significantly reduced enzyme activity, which can lead to severe neutropenia and diarrhoea after standard irinotecan administration; therefore, oncologists use this result to reduce the starting dose or select alternative therapies.
2. Can this test confirm if I have Gilbert syndrome?
Yes, detecting a homozygous (TA)7/(TA)7 or compound heterozygous promoter polymorphism strongly supports a diagnosis of Gilbert syndrome. This benign condition causes mild, fluctuating unconjugated hyperbilirubinemia and does not require treatment, but genetic confirmation helps avoid unnecessary liver investigations and provides reassurance.
3. How should I prepare for the UGT1A1 gene, and when will I receive the report?
No fasting or medication changes are required; simply provide a 4 mL whole blood sample in an EDTA tube, kept refrigerated but never frozen. Results are delivered within 7 working days from Monday/Wednesday collection, and your dedicated clinical team will call you for a confidential telephonic interpretation session.
UAE Regulatory & Data Privacy Adherence
Your data is handled in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. DNA Labs UAE is licensed by the Dubai Health Authority (DHA Facility License No. 1143) and adheres to all local health information governance standards.
Clinical & Logistical Metadata
| Test Name | UGT1A1 Gene Polymorphism (TA Repeat) Detection Test |
| Price (AED) | 1200 |
| Turnaround Time | 7 Working Days |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) |
| Methodology Used | PCR + Capillary Electrophoresis Fragment Analysis |
| ICD-10-CM Code | Z13.89 |
| LOINC Code | 21622-0 |
| DHA Facility License & Laboratory Address | DHA Facility License No: 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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