Test Price
750 AED✅ Home Collection Available
ADRB2 Genotyping for Beta‑2 Agonist Responsiveness Test in the UAE | 750 AED | DHA Guidelines
Executive Summary & Core Metrics
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- ✓ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection, available daily 8 AM – 11 PM.
- ✓ Clinical Guidance: Telephonic post‑test clinical interpretation support.
- ✓ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The ADRB2 Genotyping test identifies variants in the beta‑2 adrenergic receptor gene to predict individual response to beta‑2 agonist bronchodilators like salbutamol, enabling personalised management of asthma and COPD.
| Feature | Our Test (ADRB2 Genotyping) | Closest Alternative (Empirical Trial) |
|---|---|---|
| Precision | 99.9% sensitivity, PCR Sequencing | Subjective clinical response |
| Methodology | PCR Sequencing (DNA Sequencing) | Trial of different inhalers |
| Speed to clarity | 10 working days (definitive result) | Weeks to months of trial & error |
Physician Insight & Safety Protocols
“ADRB2 genotyping is a powerful tool to guide beta‑2 agonist selection, but it must be interpreted within the full clinical context, including spirometry and symptom history. I always advise patients to never stop or modify inhaler therapy without discussing the genetic results with their treating pulmonologist.” – Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403.
Advisory & Safety Caution
⚠️ Do not discontinue prescribed medication without consulting your doctor. Genetic results should be integrated with full clinical assessment.
Exclusion Criteria & Red Flags
- Exclusion Criteria: Inability to provide a venous blood sample (severe coagulopathy, active bleeding). Not indicated for emergency asthma diagnosis. Not suitable for children under 18 without legal guardian consent (as per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Red Flags – Seek Immediate Emergency Care: Severe shortness of breath at rest, cyanosis, inability to speak full sentences, peak flow <50% of personal best. Call 998 or go to the nearest ER.
Patient FAQ & Clinical Guidance
1. What is ADRB2 genotyping and how does it guide beta‑2 agonist therapy?
Answer: ADRB2 genotyping identifies inherited variants in the beta‑2 receptor gene that influence bronchodilator efficacy, allowing doctors to select the most effective inhaler for each patient. The test detects common polymorphisms like Arg16Gly and Gln27Glu that alter receptor down‑regulation and response to short‑acting and long‑acting beta‑2 agonists.
2. How accurate is this and which methodology is used?
Answer: Our ISO‑certified lab uses PCR sequencing with 99.9% diagnostic sensitivity, ensuring reliable detection of key ADRB2 polymorphisms. The analysis employs bidirectional Sanger sequencing of the ADRB2 gene, covering all pharmacogenetically relevant exonic regions, processed in a DHA‑compliant facility.
3. Do I need to fast or stop medications before the blood draw?
Answer: No special preparation is required; continue all medications as prescribed unless your physician advises otherwise. Collect a 4 mL whole blood sample in an EDTA lavender‑top tube, keep refrigerated (do not freeze), and transport via our cold‑chain home collection service.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance
DNA Labs UAE strictly adheres to the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and the Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access‑controlled, and processed solely for the intended diagnostic purpose.
Clinical & Logistical Metadata
| Test Name | ADRB2 Genotyping for Beta‑2 Agonist Responsiveness |
| Price (AED) | 750 |
| Turnaround Time | 10 working days |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA lavender‑top tube) |
| Methodology Used | PCR Sequencing (Bidirectional Sanger Sequencing) |
| ICD-10-CM Code | J45.9 |
| LOINC Code | 21636-6 |
| DHA Facility License & Laboratory Address Invariants | DHA License: 1143 Address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE Lab Brand: DNA Labs UAE |
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