Test Price
1,500 AED✅ Home Collection Available
CYP3A4*22 Genotyping in UAE | 1,500 AED | DNA Labs UAE
Executive Summary & Core Metrics
Executive Summary: The CYP3A4*22 genotype test is performed at our ISO 9001:2015 accredited laboratory with 99.9% diagnostic sensitivity, utilizing VIP mobile phlebotomy with temperature-controlled cold-chain home collection, telephonic post-test clinical guidance, and direct insurance verification via WhatsApp.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CYP3A4*22 genotype test identifies a reduced-function variant in the CYP3A4 enzyme, which metabolizes over half of all clinically used drugs, allowing your physician to personalize dosing and avoid toxicity or inefficacy. This single nucleotide polymorphism (rs35599367) is associated with decreased CYP3A4 activity and has implications for drugs such as statins, tacrolimus, and certain calcium channel blockers.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Methodology | PCR + DNA Sequencing (double confirmation) | PCR only (no sequencing validation) |
| Diagnostic Precision | 99.9% Sensitivity, 100% Specificity | ~95% Sensitivity, occasional false negatives |
| Turn-Around Time | 10 Working Days | 14–21 Days |
| Sample & Logistics | Home collection, cold-chain transport | Self-visit to lab, ambient transport risk |
| Post-Test Support | Free telephonic clinical guidance | No physician consultation included |
Physician Insight & Safety Protocols
From Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403: “Understanding your CYP3A4*22 genotype is a step toward precision medicine. As a clinical geneticist, I interpret this result as one piece of a larger puzzle – always in the context of your full medication list, liver function, and other clinical factors. Dose adjustments must be done under strict medical supervision. This test does not replace the essential dialogue between you and your physician.”
Medication Advisory
Important: Do not discontinue prescribed medication without consulting your doctor. The CYP3A4*22 result should only be used by a qualified physician to guide dose adjustments. Any changes to therapy must be made by your healthcare provider to ensure safety and efficacy.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria (may affect result accuracy): Blood transfusion within the last 4 weeks, active chemotherapy, or known hematopoietic malignancy.
- Phlebotomy Caution: Severe anaemia (Hb <7 g/dL) – physician clearance may be required before blood draw.
- Procedure-Related Red Flags: If after sample collection you develop uncontrolled bleeding, large haematoma, fever or purulent discharge at the puncture site, seek immediate emergency care.
- Pharmacogenetic Red Flag: If you experience symptoms like severe muscle pain on statins or unanticipated drug reactions, contact your doctor promptly irrespective of genotype result.
Patient FAQ & Clinical Guidance
1. What is the CYP3A4*22 genotype test used for?
The CYP3A4*22 genotype test identifies a reduced-function genetic variant, predicting slower metabolism of drugs like statins, calcium channel blockers, and immunosuppressants. This information helps your doctor choose safer starting doses and avoid adverse drug reactions.
2. How is the test performed and what preparation is needed?
A simple blood sample (4 mL in an EDTA tube) is collected by a certified phlebotomist, requiring no fasting or special diet. You must complete the duly filled Genomics Clinical Information Requisition Form (Form 20) before collection. Our VIP mobile phlebotomy team arrives at your doorstep.
3. How long until I receive my results, and what is the cost?
Results are typically available within 10 working days, with the all-inclusive price set at 1,500 AED. This cost covers home collection, ISO-certified lab processing, and a telephonic post-consultation.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health ICT Compliance
This diagnostic service fully complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, access-controlled, and processed exclusively within the UAE. Clinical safety and patient consent procedures follow Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | CYP3A4*22 Genotyping (rs35599367) |
| Price (AED) | 1,500 |
| Turnaround Time | 10 Working Days |
| Sample Type / Matrix | Whole Blood (Peripheral, EDTA Tube) – Home Collection via VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain |
| Methodology Used | PCR + Sanger DNA Sequencing |
| ICD-10-CM Code | Z13.89 |
| LOINC Code | 81307-7 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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All reports reviewed by DHA-Certified physicians