Test Price
4,700 AED✅ Home Collection Available
COMT Genotyping Test in UAE | 4,700 AED | DHA Compliant Pharmacogenomics
Executive Summary & Core Metrics
The COMT Genotyping test evaluates genetic variants in the catechol-O-methyltransferase gene to guide personalized medication dosing, particularly for psychiatric and pain management therapies. This assay delivers 99.9% diagnostic sensitivity via ISO-accredited processing at our Dubai Healthcare City laboratory.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO‑Accredited Processing
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily 8 AM–11 PM)
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance by a Consultant Medical Genetics
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
The COMT genotyping assay identifies single nucleotide polymorphisms (SNPs) within the catechol-O-methyltransferase gene that influence the metabolism of catecholamine neurotransmitters. This pharmacogenomic assessment enables clinicians to tailor psychotropic and analgesic therapies based on individual metabolic capacity, improving therapeutic outcomes and reducing adverse drug reactions.
| Feature | Our Test (DHA‑ISO) | Standard Alternative |
|---|---|---|
| Precision | Allele‑specific PCR + Sanger validation (99.9% sensitivity) | Generic PCR with lower variant resolution |
| Methodology | LC‑MS/MS‑verified genotyping & DHA pharmacogenomic protocol | Basic DNA sequencing without mass spectrometry validation |
| Turnaround | 10 working days (sample received by 11 am) | 14–21 days |
| Support | 24/7 WhatsApp clinical guidance & direct insurance billing | Email‑only, limited insurance help |
Physician Insight & Safety Protocols
Consultant Medical Genetics Lina Osama Zaki Quteineh (DHA Registration ID: 9294403) advises: “COMT genotyping provides critical pharmacokinetic data, but results must be contextualized within the complete clinical history. This test identifies metabolic pathways influencing drug efficacy and side-effect profiles; it is not a standalone diagnostic tool. Always share your genotype report with your treating physician for personalized therapy adjustments.”
Clinical Advisory — Important Safety Information
Do not alter or discontinue any prescribed medication based solely on genetic test results without prior consultation with your treating physician. This genotyping assay is intended to support clinical decision-making, not to replace it. All sample collection procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability governing patient safety and informed consent.
Exclusion Criteria & Specimen Rejection
- Testing is not recommended for individuals currently experiencing acute psychiatric distress requiring immediate crisis intervention.
- Minors require written informed consent from a legal guardian; testing will not proceed without proper guardian authorization.
- Specimen rejection: improperly completed Genomics Clinical Information Requisition Form (Form 20) or a frozen/hemolyzed EDTA whole blood sample — such specimens will be rejected and recollection requested.
Patient FAQ & Clinical Guidance
1. What is COMT genotyping and how does it influence my medication?
COMT genotyping identifies gene variants that alter the metabolism of catecholamine neurotransmitters, directly affecting drug efficacy, dosage, and side‑effect risks. This genetic information allows your physician to adjust psychotropic or pain medications for safer, more effective therapy.
2. How should I prepare for the blood draw, and why is the Genomics Clinical Information Requisition Form mandatory?
No special fasting is required. The Genomics Clinical Information Requisition Form (Form 20) captures essential family history and drug exposure data necessary for accurate interpretation. This form is a mandatory regulatory component per DHA guidelines and must accompany the refrigerated lavender‑top EDTA whole blood sample collected during your scheduled home phlebotomy visit.
3. What do my COMT genotype results mean for my current psychiatric or pain management treatment?
Your COMT result classifies you as a normal, intermediate, or slow metabolizer, helping your doctor anticipate drug plasma levels and adjust doses of levodopa, antidepressants, or analgesics accordingly. It does not replace clinical monitoring but adds a powerful genomic safety layer to prevent under‑ or over‑dosing.
UAE Regulatory & Data Privacy Adherence
All genetic data processing and storage at DNA Labs UAE complies fully with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient genomic information is encrypted, access‑controlled, and never shared without explicit written consent. Our laboratory infrastructure is ISO 9001:2015 certified and operates under DHA Facility License Number 1143.
Clinical & Logistical Metadata
| Test Name | COMT Genotyping Test |
| Price (AED) | 4,700 AED |
| Turnaround Time | 10 working days (sample received by 11 am) |
| Sample Type / Matrix | Peripheral Whole Blood (Lavender‑top EDTA) |
| Methodology Used | Allele‑specific PCR + Sanger validation (LC‑MS/MS‑verified) |
| ICD-10-CM Code | Z13.89 |
| LOINC Code | 94436-2 |
| DHA Facility License & Laboratory Address | License 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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