Test Price
900 AED✅ Home Collection Available
Cytochrome P450 2D6 (CYP2D6) Genotyping in UAE | 900 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
Test Overview & Methodology
CYP2D6 genotyping is a pharmacogenomic test that identifies inherited variations in the cytochrome P450 2D6 gene, which governs the metabolism of over 25% of clinically used drugs. For UAE patients, this test empowers gynecologists, anti‑aging specialists, and clinical pharmacologists to personalise tamoxifen, antidepressant, and opioid therapies – reducing adverse reactions and improving outcomes.
| Feature | Our Test (Sanger Gold‑Standard) | Closest Alternative (Microarray Panel) |
|---|---|---|
| Methodology | Bidirectional Sanger Sequencing + Copy Number Analysis | SNP‑based microarray with limited variant coverage |
| Accuracy & Precision | 99.9% – detects rare alleles (e.g., *4, *10, *17, duplications) | 95% – misses uncommon/novel variants |
| Turnaround Time | 10–12 working days | 15–20 working days |
| Regulatory Endorsement | DHA/MOHAP licensed facility, ISO 9001:2015 | Basic CLIA only |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
“CYP2D6 genotyping results must always be interpreted alongside the patient’s medication list and clinical history. A poor metaboliser status does not automatically contraindicate a drug; therapeutic alternatives and dose modifications should be discussed with the prescribing physician. Genotype‑guided prescribing reduces adverse drug reactions and improves efficacy, particularly for tamoxifen, codeine, and antidepressants.”
Advisory Notice
⚠️ Medication Warning
Do not discontinue prescribed medication without consulting your doctor. Genotype‑guided dose adjustments must be supervised by the treating clinician.
Exclusion Criteria & Red Flags
🚨 Safety Exclusion Criteria
- Exclusions: Active pregnancy (unless prescribed by consultant obstetrician), major surgery scheduled within 48 hours, known coagulation disorder preventing safe phlebotomy.
- Red Flags – Seek Immediate Medical Attention: Sudden onset of jaundice or severe abdominal pain while on CYP2D6‑substrate drugs, signs of opioid overdose (respiratory depression, pinpoint pupils), or severe serotonin syndrome (agitation, hyperthermia) if on serotonergic agents.
Patient FAQ & Clinical Guidance
1. What is CYP2D6 genotyping and why do I need it?
CYP2D6 genotyping identifies genetic variations that influence how your body metabolises drugs like tamoxifen, codeine, and antidepressants. Based on your metaboliser status (poor, intermediate, extensive, or ultra‑rapid), your doctor can tailor the drug choice and dosage, reducing the risk of toxicity or therapeutic failure.
2. Will my insurance cover CYP2D6 genotyping in the UAE?
Many leading UAE insurers now reimburse CYP2D6 genotyping when prescribed by a DHA‑licensed gynecologist, anti‑aging specialist, or clinical pharmacologist under medical necessity. Contact our billing team via WhatsApp at +971 54 548 8731 with your insurance card to verify coverage instantly.
3. How should I prepare for the blood sample collection?
You must present a valid doctor’s prescription (except for surgery, pregnancy, or travel purposes). No fasting is needed; a single peripheral blood draw is taken by our DHA‑certified phlebotomist at your home, following strict cold‑chain handling to ensure sample integrity.
4. How long does it take to get results?
The turnaround time is 10–12 working days from sample receipt. You will receive a comprehensive report including genotype, metaboliser phenotype, and pharmacogenomic recommendations.
5. Can I change my medication based on the results alone?
No, you should never alter your medication without consulting your prescribing physician. The results provide guidance, but all dose adjustments must be clinically supervised.
UAE Regulatory & Data Privacy Adherence
Your Data, Your Rights
DNA Labs UAE operates under the framework of Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic data is encrypted, anonymised, and used solely for the purpose of clinical testing. No data is shared with third parties without explicit patient consent, as mandated by Federal Decree‑Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | Cytochrome P450 2D6 (CYP2D6) Genotyping |
| Price (AED) | 900 AED |
| Turnaround Time | 10–12 working days |
| Sample Type / Matrix | Whole Blood (peripheral) – VIP Home Collection & Temperature‑Controlled Cold‑Chain Logistics |
| Methodology Used | Bidirectional Sanger Sequencing + Copy Number Analysis (CNV) |
| ICD-10-CM Code | Z13.89 (Encounter for screening for other diseases and disorders) |
| LOINC Code | 81856-6 (CYP2D6 gene full gene analysis) |
| DHA Facility License & Laboratory Address | DHA Facility License: 1143 | DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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