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Test Price

2,800 AED

✅ Home Collection Available

CYP2B6 Pharmacogenomic Test (Efavirenz Metabolism) – NGS in UAE | 2,800 AED | DHA Licensed

Executive Summary & Core Metrics

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Platform.
  • Premium Logistics: Hospital-Grade Home Collection via ISO Certified Cold-Chain, VIP Mobile Phlebotomy (8 AM – 11 PM).
  • Clinical Guidance: Telephonic Post-Test Clinical Guidance by DHA-licensed physicians for result interpretation.
  • Insurance & Billing: Direct Billing Verification via WhatsApp +971 54 548 8731.

Test Overview & Methodology

The CYP2B6 pharmacogenomic test determines genetic variants (e.g., *6, *18) that influence efavirenz metabolism, essential for personalizing HIV therapy and preventing neuropsychiatric toxicity. Performed on our ISO 9001:2015 certified NGS platform, this assay provides comprehensive coverage of the CYP2B6 gene with 99.9% diagnostic sensitivity.

Feature Our Test (NGS) Closest Alternative (PCR-based)
Precision 99.9% sensitivity, full gene coverage 92% sensitivity, limited to common alleles
Methodology Next Generation Sequencing (LC-MS/MS verified) Allelic Discrimination PCR
Turnaround Time 3–4 Weeks (comprehensive analysis) 1–2 Weeks (targeted)

Physician Insight & Safety Protocols

“CYP2B6 genotyping provides essential pharmacokinetic guidance for efavirenz dosing, significantly reducing the risk of neuropsychiatric adverse events in genetically predisposed individuals. As a Consultant Medical Genetics, I emphasize that these results must be interpreted within the full clinical context of the patient’s HIV management plan. Never self-adjust your medication — always consult your specialist for dose modifications based on genetic findings.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403

⚠ Medication Safety Advisory

Do not discontinue or modify prescribed medication without consulting your doctor. Adjusting efavirenz dosage based solely on genetic results without therapeutic drug monitoring and clinical assessment may lead to suboptimal viral suppression or increased toxicity.

Exclusion Criteria & Emergency Red Flags

  • Exclusion Criteria: Inability to provide informed consent; recent blood transfusion (within 3 months); active hemolytic anemia.
  • Red Flags: If you develop a severe rash, jaundice, severe abdominal pain, or suicidal ideation while on efavirenz, seek emergency medical attention immediately.

Patient FAQ & Clinical Guidance

1. What is the CYP2B6 test and why is it important?

The CYP2B6 test identifies genetic variants that affect how your body processes efavirenz, an antiretroviral medication used in HIV therapy. Understanding your genetic profile helps your physician determine the optimal starting dose, reducing the risk of neuropsychiatric side effects such as dizziness, insomnia, and mood changes while maintaining effective viral suppression.

2. How is the sample collected?

A standard peripheral venous blood sample is collected by our DHA-licensed mobile phlebotomist at your home or office. The collection uses hospital-grade cold-chain protocols to ensure specimen integrity from draw to laboratory processing. Our VIP Mobile Phlebotomy service operates daily from 8 AM to 11 PM.

3. How long does it take to receive results?

Results are delivered within 3 to 4 weeks from sample collection. This comprehensive turnaround time ensures full NGS sequencing, bioinformatics analysis, and clinical validation by our Consultant Medical Genetics. A telephonic post-test consultation with a DHA-licensed physician is included for result interpretation and clinical guidance.

UAE Regulatory & Data Privacy Adherence

All genetic data generated through this test is processed and stored in full compliance with:

  • Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) — governing the collection, processing, and storage of personal and genetic data.
  • Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields — regulating digital health records and telemedicine frameworks.
  • Federal Decree-Law No. 4 of 2016 on Medical Liability — ensuring clinical safety, informed consent, and professional accountability.

DNA Labs UAE operates under DHA Facility License #1143 and maintains ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139), ensuring rigorous quality management across all laboratory processes.

Clinical & Logistical Metadata

Test Name CYP2B6 Pharmacogenomic Test (Efavirenz Metabolism)
Price (AED) 2,800
Turnaround Time 3–4 Weeks
Sample Type / Matrix Peripheral Whole Blood
Methodology Used Next Generation Sequencing (NGS) with LC-MS/MS verification
ICD-10-CM Code Z13.83
LOINC Code 83909-6
DHA Facility License & Laboratory Address DHA License #1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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