Test Price
2,800 AED✅ Home Collection Available
ABCB1 Gene Colchicine Resistance Genetic Test in UAE
| 2800 AED | 2026 DHA Guidelines
تحليل جين ABCB1 لمقاومة الكولشيسين في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
الموثوقية والامتثال الإماراتي ضمان الدقة: حساسية تشخيصية بنسبة 99.9% عبر مختبر حاصل على شهادة ISO 9001:2015. خدمة سحب الدم المنزلي المتميزة بنظام النقل المبرد المعتمد. استشارة سريرية هاتفية بعد الفحص لتفسير النتائج مع أطباء متخصصين. تحقق من التغطية التأمينية عبر واتساب +971 54 548 8731.
Premium Logistics: ISO-Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM). Clinical Guidance: Telephonic Post-Test Interpretation by DHA-Licensed Specialists. Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The ABCB1 Gene Colchicine Resistance Genetic Test is a targeted pharmacogenomic assay that analyzes the ABCB1 gene variants responsible for altered colchicine response, guiding precise therapeutic dosing and alternative therapy decisions. هذا الفحص الجيني المتطور يكشف طفرات جين ABCB1 المرتبطة بمقاومة دواء الكولشيسين، مما يساعد الأطباء في تخصيص العلاج.
| Feature | Our Test (NGS) | Closest Alternative (PCR Single-Locus) |
|---|---|---|
| Precision & Sensitivity | 99.9% Diagnostic Sensitivity, covers all known ABCB1 variants | ~85% accuracy, limited to 2–3 common polymorphisms |
| Methodology | Next-Generation Sequencing (NGS) with confirmatory Sanger validation | Real-Time PCR / RFLP |
| Turnaround Time | 3 to 4 Weeks (comprehensive report) | 1–2 Weeks (incomplete variant coverage) |
Physician Insight & Safety Protocol
"As a DHA-licensed clinical pathologist, I emphasize that this ABCB1 genotype must be correlated with the patient’s full clinical picture—including colchicine tolerance, renal function, and co-medications—before any therapeutic decision. This test does not replace clinical judgment but offers a robust genetic compass for personalised dosing. Any dose adjustment must always be supervised by the prescribing physician."
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠️ Critical Medication Warning
Do not discontinue prescribed colchicine or any other medication without consulting your doctor. A genotype result indicating potential resistance does not imply an immediate need to stop therapy; abrupt changes can trigger severe flares of gout or familial Mediterranean fever.
Patient Safety – Exclusion & Red Flags
- Exclusion Criteria: Active febrile infection, known haematopoietic disorder affecting blood collection, or recent blood transfusion within 2 weeks (may introduce donor DNA artefacts).
- Emergency Red Flags: If you experience severe muscle weakness, numbness, or signs of colchicine toxicity (nausea, vomiting, diarrhoea, abdominal pain) even at usual doses, seek emergency care immediately. These symptoms may signal life-threatening toxicity before genetic results are available.
- Pre-Test Requirement: A pre-test genetic counselling session (included) to document your family history and obtain informed consent is mandatory for all UAE patients under Federal Decree-Law No. 41 of 2024.
Patient FAQ & Clinical Guidance
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التحقق من التغطية التأمينية
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians