Test Price
700 AED✅ Home Collection Available
PDGFRβ (CMML) Gene Rearrangement Test in UAE | 700 AED | 2026 DHA Guidelines
تحليل PDGFRβ (CMML) في الإمارات | 700 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي
دقة تشخيصية 99.9% عبر مختبر معتمد من ISO، مع خدمة سحب منزلي بمستوى المستشفى ودعم تأميني فوري.
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
Premium Logistics: Paid Hospital‑Grade Home Collection with ISO‑Certified Cold‑Chain and VIP Mobile Phlebotomy (8 AM – 11 PM).
Clinical Guidance: Telephonic Post‑Test Result Interpretation by an Oncology Specialist.
Insurance: Direct Billing Verification via WhatsApp
+971 54 548 8731.
Clinical Overview
The PDGFRβ (CMML) FISH test precisely detects rearrangements of the platelet‑derived growth factor receptor beta gene, a key driver of chronic myelomonocytic leukemia, enabling targeted therapy with tyrosine kinase inhibitors. يكشف فحص FISH لجين PDGFRβ عن إعادة الترتيب الجيني المسبب لابيضاض الدم النقوي المزمن ليساعد في توجيه العلاج الموجه.
| Feature | Our Test (PDGFRβ FISH) | Closest Alternative (NGS Myeloid Panel) |
|---|---|---|
| Precision / Method | Fluorescence In‑Situ Hybridization (FISH), single‑gene resolution | Next‑Generation Sequencing (multi‑gene broad panel) |
| Turnaround Time | 3–4 days | 10–14 days |
| Cost | 700 AED | >3,000 AED (typical) |
| Clinical Utility | Direct CMML confirmation & imatinib sensitivity prediction | Broad mutation profiling, longer interpretation |
Physician Insight & Safety Protocol
This test is a vital component of a comprehensive clinical evaluation; results must be correlated with morphology and other laboratory findings. Do not discontinue any prescribed medication without consulting your doctor. If you experience acute bleeding, fever, or sudden debilitating fatigue, seek emergency care immediately.
— Dr. PRABHAKAR REDDY, DHA: 61713011, Consultant Oncologist & Precision Medicine Specialist
Safety Exclusion Criteria & Emergency Red Flags
- Unsupervised self‑request for minors (UAE CDS Law 2026).
- Patient without a valid UAE physician prescription, unless for surgery clearance, pregnancy screening, or official travel abroad (Federal Decree‑Law No. 41 of 2024, Art. 87).
- Active severe infection (e.g., sepsis) that may compromise sample integrity or patient stability.
🚨 Seek immediate emergency care if you develop new‑onset easy bruising, spontaneous bleeding, persistent fever >38.5°C, or sudden profound fatigue.
⚠️ Medication Warning: Do not discontinue any prescribed medication without consulting your doctor.
Patient FAQ & Clinical Guidance
1. What is the purpose of the PDGFRβ (CMML) FISH test?
Answer: PDGFRβ FISH testing detects gene rearrangements in chronic myelomonocytic leukemia to guide targeted inhibitor therapy.
This assay specifically identifies the 5q32‑33 PDGFRβ rearrangement, confirming the diagnosis of CMML and predicting a favourable response to imatinib and other tyrosine kinase inhibitors. It is performed on bone marrow aspirate or peripheral blood and offers a rapid, cost‑effective alternative to broader sequencing.
الجواب: يكشف اختبار FISH لجين PDGFRβ عن إعادة الترتيب في ابيضاض الدم النقوي المزمن لتوجيه العلاج بالمثبطات المستهدفة.
2. How is the sample collected and what are the pre‑ requirements?
Answer: A doctor’s prescription is mandatory for bone marrow or peripheral blood collection by a trained phlebotomist.
Our mobile phlebotomy team visits your home between 8 AM and 11 PM daily using ISO‑certified cold‑chain transport. A valid UAE physician prescription is required, except for surgery clearance, pregnancy work‑up, or mandatory travel documentation. Fasting is not necessary. The sample (2‑3 mL bone marrow aspirate or 5 mL peripheral blood in EDTA tube) is processed immediately upon arrival.
الجواب: لا بد من وصفة طبية سارية لأخذ عينة نخاع عظمي أو دم محيطي بواسطة فني سحب مرخص.
3. What do positive or negative results indicate for CMML?
Answer: A positive PDGFRβ rearrangement confirms CMML and indicates potential sensitivity to targeted kinase inhibitor therapy.
A positive FISH signal proves a PDGFRβ rearrangement, classifying the CMML and making it highly responsive to imatinib. A negative result does not exclude CMML; it may indicate an alternate molecular driver and may require extended NGS testing. All results are reviewed by our oncology specialist, who is available for telephonic interpretation.
الجواب: تؤكد إعادة الترتيب الإيجابية لجين PDGFRβ الاصابة بابيضاض الدم النقوي المزمن وتشير إلى حساسية محتملة للعلاج بمثبطات الكيناز.
This service complies with UAE Federal Decree‑Law No. 41 of 2024 (Art. 87), UAE Child Digital Safety Law 2026, and UAE PDPL. Patient data is processed solely for diagnostic purposes under strict confidentiality.
ISO 9001:2015 Certificate: INT/EGQ/2509DA/3139 | DHA Licensed Facility: 9834453 | Support: +971 54 548 8731.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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