Test Price
2,800 AED✅ Home Collection Available
NDUFAF6 Gene Leigh Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل الحمض النووي لجين NDUFAF6 لمتلازمة لي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
- Premium Logistics: Paid Hospital‑Grade Home Collection via ISO Certified Cold‑Chain Home Collection and VIP Mobile Phlebotomy (8 AM‑11 PM).
- Clinical Guidance: Telephonic Post‑Test Clinical Guidance in Result Interpretation by a DHA‑licensed specialist.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
الخلاصة التنفيذية: يوفر هذا التحليل الجيني المتقدم باستخدام تقنية التسلسل من الجيل التالي (NGS) تشخيصًا دقيقًا لجين NDUFAF6 المرتبط بمتلازمة لي، وذلك وفق أعلى معايير هيئة الصحة بدبي ودقة تشخيصية تصل إلى 99.9%. تتضمن الخدمة سحبًا منزليًا مع سلسلة تبريد معتمدة، واستشارة طبية بعد النتائج، ودعمًا مباشرًا للفوترة التأمينية.
Test Overview
The NDUFAF6 Gene Leigh Syndrome Genetic Test analyzes the entire coding region of the NDUFAF6 gene using next‑generation sequencing to detect pathogenic variants responsible for Leigh syndrome, a severe neurometabolic disorder. This test is designed for individuals with clinical suspicion of Leigh syndrome spectrum disorders, offering a definitive molecular diagnosis and guiding critical management decisions. (يكشف هذا الاختبار الطفرات المسببة لمتلازمة لي في جين NDUFAF6 بدقة فائقة)
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | Full gene NGS with Sanger validation for all pathogenic/likely pathogenic variants | Targeted mutation panel or single‑gene Sanger only (limited coverage) |
| Methodology | Next‑Generation Sequencing (Illumina® platform) + integrated Sanger confirmation | Conventional Sanger sequencing (slower, no large rearrangement detection) |
| Turnaround Time | 3 to 4 Weeks (including validation) | Often 6–8 Weeks without bioinformatics integration |
Physician Insight & Safety Protocol
“As a consultant neurologist, I know how overwhelming it can be to face a possible genetic diagnosis for your loved one. The NDUFAF6 test provides a clear molecular answer, but every result must be weighed together with your child’s full clinical picture. Please be assured that no result will be released without expert interpretation.”
— Dr. Prabhakar Reddy, DHA License 61713011, Consultant Neurologist
⚠️ Medication Warning: Do not discontinue, modify, or start any medication based on this test result without explicit consultation with your treating physician.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Test not indicated for asymptomatic minors without comprehensive genetic counseling and signed informed consent by the legal guardian, as mandated by UAE CDS Law 2026 (Minors). Also exclude adults without clinical suggestion of Leigh spectrum disorder.
- Emergency Warning: If the individual develops sudden neurological deterioration, seizures, respiratory distress, or severe metabolic acidosis, seek emergency medical attention immediately. This test is not a substitute for acute clinical intervention.
Patient FAQ & Clinical Guidance
1. Why is the NDUFAF6 gene important for Leigh syndrome?
The NDUFAF6 gene encodes a mitochondrial complex I assembly factor; pathogenic variants disrupt cellular energy production, causing the characteristic neurological and metabolic features of Leigh syndrome. يعد جين NDUFAF6 ضروريًا لتشغيل الميتوكوندريا، وأي طفرة تؤدي إلى متلازمة لي العصبية الاستقلابية.
2. How is the sample collected for this genetic test?
A simple blood draw, extracted DNA, or a single drop of blood on an FTA card can be used, with our VIP home collection team arriving within 60 minutes in Dubai and Sharjah. يمكن جمع العينة عن طريق سحب الدم أو قطرة دم على بطاقة FTA، ويصل فريقنا المنزلي خلال 60 دقيقة.
3. What is the accuracy and clinical validity of this test?
The test achieves 99.9% diagnostic sensitivity for single nucleotide variants and small indels within the NDUFAF6 gene when performed under our ISO‑accredited NGS protocol with orthogonal confirmation. تصل حساسية الاختبار إلى 99.9% للطفرات النقطية والإدخالات/الحذف الصغيرة، بفضل منهجية NGS المعتمدة.
🔬 Regulatory & E-E-A-T Compliance
- performed in strict adherence to Federal Decree-Law No. 41 of 2024 (Art. 87) (Genetic Testing and Data Privacy), UAE PDPL, and CDS Law 2026 (Minors’ Consent Protocols).
- ISO 9001:2015 Certified Laboratory – Cert No: INT/EGQ/2509DA/3139. Facility License: 9834453.
- Medical Director: Dr. Prabhakar Reddy, DHA 61713011. All results reviewed by a board‑certified consultant.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians