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Test Price

4,800 AED

✅ Home Collection Available

Hemochromatosis HFE Full Gene Sequence Analysis in Dubai, UAE – 4,800 AED – DHA Licensed Lab

Executive Summary & Core Metrics

This genetic test uses gold‑standard Sanger sequencing to detect pathogenic variants in the HFE gene, essential for diagnosing hereditary hemochromatosis. Core metrics include a diagnostic sensitivity of >99.9%, a turnaround time of 4–6 business weeks, and a fixed price of 4,800 AED. Logistics are supported by VIP mobile phlebotomy and ISO‑certified cold‑chain home collection (daily 8 AM – 11 PM). Post‑test telephonic clinical guidance is provided by our DHA‑licensed genetics specialist.

  • Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing
  • Premium Logistics: Hospital‑Grade Home Collection with ISO‑Certified Cold‑Chain Transport and VIP Mobile Phlebotomy
  • Clinical Guidance: Telephonic Post‑Test Interpretation with DHA‑Consultant Medical Geneticist
  • Insurance Support: Direct Billing Verification via WhatsApp at +971 54 548 8731

Test Overview & Methodology

The HFE Full Gene Sequence Analysis employs Sanger sequencing with capillary electrophoresis, the gold standard for detecting single‑nucleotide variants and small insertions/deletions in the HFE gene. This test covers the entire coding region and exon‑intron boundaries, identifying variants such as C282Y, H63D, S65C, and other clinically relevant mutations. It is indicated for patients with elevated serum ferritin, unexplained arthritis, diabetes, or hypogonadism, bridging the needs of gynecologists, rheumatologists, and anti‑aging specialists in the UAE.

Feature Our Test Closest Alternative
Precision 99.9% sensitivity for HFE C282Y, H63D, S65C Limited to hotspot genotyping only
Methodology Sanger Sequencing (Capillary Electrophoresis) – Gold Standard Often PCR‑based targeted mutation analysis
Turnaround Speed 4–6 weeks with full clinical report Variable; may require follow‑up testing

Physician Insight & Safety Protocols

“This test is a cornerstone for uncovering hidden iron overload before irreversible organ damage occurs. However, a positive genetic result must always be correlated with serum ferritin, transferrin saturation, and clinical symptoms. Never interpret it in isolation – a thorough clinical evaluation remains paramount.”

— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403

Advisory: Medication and Therapy Precautions

Do not discontinue prescribed medications or iron chelation therapy without consulting your doctor. Improper adjustment can lead to severe iron‑related complications.

Safety Exclusion Criteria & Emergency Red Flags

  • Active acute infection or febrile illness – reschedule after recovery.
  • Recent blood transfusion (within 4 weeks) may transiently alter iron studies; wait 4 weeks post‑transfusion.
  • If you experience sudden severe abdominal pain, massive vomiting, or confusion, seek immediate emergency care – these may indicate acute iron toxicity unrelated to genetic testing.

Patient FAQ & Clinical Guidance

1. Who should consider this HFE full gene sequence test?

This test is indicated for adults with elevated ferritin, unexplained arthritis, diabetes, or hypogonadism. A 15‑word direct answer: It is for patients with suspected hereditary iron overload not explained by diet or other causes.

2. Is a doctor’s prescription required, and are there any exemptions?

A valid DHA‑licensed prescription is mandatory except for pre‑surgery, pregnancy, or travel fitness clearance. A 15‑word direct answer: Prescription required unless for pre‑operative, antenatal, or travel fitness purposes.

3. What is the accuracy and reliability of this genetic test?

Our Sanger sequencing achieves >99.9% sensitivity and specificity for clinically relevant HFE mutations. A 15‑word direct answer: It has >99.9% accuracy for detecting all clinically important HFE variants.

UAE Regulatory & Data Privacy Adherence

This diagnostic service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is stored in encrypted servers, accessed only by authorized medical personnel, and never shared without explicit patient consent. The laboratory holds a valid DHA Facility License (No. 1143) and adheres to DHA’s standards for genetic testing and patient privacy.

Clinical & Logistical Metadata

Test Name Hemochromatosis HFE Full Gene Sequence Analysis
Price (AED) 4,800 AED
Turnaround Time 4–6 business weeks
Sample Type / Matrix Peripheral whole blood (3–5 mL in EDTA tube) – VIP Mobile Phlebotomy Available
Methodology Used Sanger Sequencing (Capillary Electrophoresis)
ICD-10-CM Code E83.110
LOINC Code 94217-3
DHA Facility License & Laboratory Address License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE

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