Test Price
2,800 AEDโ Home Collection Available
TMPRSS3 Gene Deafness, Autosomal Recessive Type 8/10 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing (Cert: INT/EGQ/2509DA/3139).
Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection; VIP Mobile Phlebotomy available 8 AM โ 11 PM.
Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed expert.
Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test analyzes the TMPRSS3 gene via next-generation sequencing (NGS) to provide definitive molecular diagnosis of autosomal recessive nonsyndromic hearing loss types DFNB8 and DFNB10. The test enables early intervention and informed family planning for affected individuals and at-risk relatives.
| Feature | Our Test (TMPRSS3 NGS) | Conventional SingleโGene Testing |
|---|---|---|
| Precision | 99.9% analytical sensitivity, full coding region coverage | Limited to known hotspot variants; may miss rare mutations |
| Method | NGS with bioinformatic validation, CLIA-certified | Sanger sequencing (targeted) |
| Turnaround Time | 3โ4 Weeks (express available) | 4โ6 Weeks |
Physician Insight & Safety Protocols
"TMPRSS3 genetic analysis is most clinically valuable when integrated with a complete audiologic phenotype and detailed family history. A positive result requires careful correlation with clinical presentation, as not all identified variants are proven pathogenic. Post-test genetic counseling remains essential for all patients and their families."
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Important Medication Advisory
Do not stop or modify any prescribed medications without consulting your treating physician. Genetic test results provide diagnostic information and do not replace ongoing clinical monitoring or established treatment plans.
Safety & Exclusion Criteria
- This test is not indicated for acquired hearing loss resulting from noise exposure, infection, or ototoxic medications.
- Patients requiring emergency cochlear implantation should not delay surgery pending genetic results.
- Minors (under 18 years) must have parental or legal guardian consent in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
- Specimen transport must follow ISO-certified cold chain protocols; samples compromised in transit will be rejected.
Patient FAQ & Clinical Guidance
1. What is the accuracy of the TMPRSS3 NGS test for hereditary deafness?
Our NGS platform achieves 99.9% analytical sensitivity, detecting single nucleotide variants and small insertions/deletions with clinical-grade precision across the entire TMPRSS3 coding region.
The methodology incorporates trio analysis and rigorous bioinformatic filtering to minimize false-positive reporting, ensuring reliable results for clinical decision-making.
2. How long does it take to receive results and is home collection available?
Results are typically available within 3 to 4 weeks from sample receipt. Express processing is available upon request for urgent clinical cases.
Yes, VIP mobile phlebotomy and temperature-controlled cold-chain home collection is available daily from 8 AM to 11 PM across Dubai and major UAE cities. Direct insurance billing can be verified in advance via WhatsApp.
3. Does health insurance cover TMPRSS3 genetic testing in the UAE?
Many UAE health insurance plans provide coverage for genetic hearing loss testing. Send your policy details via WhatsApp to +971 54 548 8731 for instant pre-approval verification and direct billing confirmation.
We handle direct billing with all major UAE insurers, minimizing out-of-pocket expenses for covered members.
UAE Regulatory & Data Privacy Adherence
All genetic testing and personal data handling at DNA Labs UAE strictly complies with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ governing all patient data processing, storage, and sharing.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ regulating digital health records and telemedicine consultations.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ ensuring patient consent, clinical safety, and professional accountability throughout the testing pathway.
Our laboratory maintains ISO 9001:2015 certification and adheres to CLIA-equivalent quality standards for molecular diagnostics.
Clinical & Logistical Metadata
| Test Name | TMPRSS3 Gene Deafness, Autosomal Recessive Type 8/10 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks (express available on request) |
| Sample Type / Matrix | Peripheral whole blood (3-5 mL in EDTA tube) โ VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM โ 11 PM |
| Methodology Used | Next-Generation Sequencing (NGS) โ full coding region analysis with bioinformatic variant interpretation |
| ICD-10-CM Code | H90.3 (Sensorineural hearing loss, bilateral) |
| LOINC Code | 21636-6 (Hearing loss genetic test) |
| DHA Facility License & Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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HIPAA
All reports reviewed by DHA-Certified physicians