Test Price
2,800 AED✅ Home Collection Available
SYNE4 Gene Deafness (Autosomal Recessive Type 76) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SYNE4 للصمم الوراثي المتنحي من النوع 76 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary / الملخص التنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO-Accredited NGS Processing – clinically validated for DFNB76 hearing loss.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO-Certified Cold-Chain, VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic post-test clinical interpretation included with every result.
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
يقدم هذا الفحص الجيني المتقدم باستخدام تقنية التسلسل الجيني الشامل (NGS) للكشف عن الطفرات في جين SYNE4 المرتبط بالصمم الوراثي من النوع 76، بدقة تشخيصية تصل إلى 99.9% ضمن مختبر معتمد آيزو، مع خدمة سحب منزلي معقمة ومحترفة.
Test Overview
The SYNE4 gene NGS test screens for pathogenic variants linked to autosomal recessive deafness type 76 (DFNB76), providing a precise molecular diagnosis for congenital or early‑onset sensorineural hearing loss. هذا الفحص الجيني يستخدم التسلسل عالي الإنتاجية لتأكيد الطفرة المسؤولة عن الصمم الوراثي من النوع 76.
| Feature | Our Test (NGS – SYNE4 Full Gene) | Closest Alternative (Sanger Sequencing Panel) |
|---|---|---|
| Methodology | Next‑Generation Sequencing (NGS) – whole gene coverage | Sanger sequencing – limited to known hotspots |
| Detection Rate | >99% of coding variants (SNVs, indels) | ~85% (only targeted regions) |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
| Price | 2800 AED | Varies (≥2500 AED without genetic counseling) |
| Post‑Test Genetic Counselling | Included (telephonic) | Often extra |
Physician Insight & Safety Protocol
"Genetic hearing loss diagnosis requires careful correlation with comprehensive audiological findings. This test identifies the underlying etiology but does not replace a full ENT evaluation or newborn hearing screening. Early intervention, when indicated, remains critical for optimal speech and language development."
— Dr. Prabhakar Reddy, Senior ENT & Genetic Consultant, DHA License No. 61713011
Medication Warning: Do not discontinue any prescribed medication without consulting your treating physician.
Safety Exclusion Criteria & ER Red Flags
- Exclusion: Inability to provide informed consent; for minors, parental/legal guardian consent is mandatory per UAE CDS Law 2026.
- Exclusion: Active severe bleeding disorder (consult physician before blood draw).
- ER Red Flags – Do Not Rely on This Test if: Sudden hearing loss, acute dizziness with fever, recent head trauma, or any emergency symptoms – seek immediate hospital care.
Frequently Asked Questions (FAQs)
Q1: What does the SYNE4 gene test detect?
It identifies disease‑causing mutations in the SYNE4 gene responsible for hereditary sensorineural hearing loss. The SYNE4 gene encodes a protein critical for inner ear hair cell function; biallelic pathogenic variants cause autosomal recessive deafness type 76 (DFNB76). This test screens all coding exons using NGS to confirm the diagnosis or carrier status.
يكشف هذا الفحص عن الطفرات المسببة للمرض في جين SYNE4 المسؤول عن الصمم الوراثي الحسي العصبي.
Q2: How is the sample collected for this genetic test?
A simple blood draw or DNA sample via buccal swab or FTA card ensures minimal discomfort. Our phlebotomist arrives at your home, collects the specimen using cold‑chain transport, and sends it to the ISO‑certified lab. No fasting or special preparation is required; the pre‑test genetic counselling session can be done virtually.
يتم جمع العينة بسحب دم بسيط أو مسحة من داخل الخد أو بطاقة FTA، دون ألم يذكر وتحت ظروف نقل مبردة معقمة.
Q3: How long do results take and what is the cost?
Results are typically ready in 3 to 4 weeks, and the price is 2800 AED inclusive of genetic counseling. The final report includes variant classification (pathogenic, likely pathogenic, VUS), clinical correlation, and guidance for family screening. Insurance direct billing is verified via WhatsApp before your appointment.
تظهر النتائج عادة خلال 3 إلى 4 أسابيع، وتكلفة الفحص 2800 درهم تشمل الاستشارة الوراثية عبر الهاتف.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians