Test Price
2,800 AED✅ Home Collection Available
SLC26A4 Gene Pendred Syndrome Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SLC26A4 لمتلازمة بيندريد في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
الملخص التنفيذي – الفحص الجيني الدقيق لمتلازمة بيندريد
يوفّر تحليل التسلسل الجيني من الجيل التالي (NGS) لجين SLC26A4 تشخيصاً دقيقاً لمتلازمة بيندريد، وهي حالة وراثية جسمية متنحية ترتبط بفقدان السمع الحسي العصبي وتضخم الغدة الدرقية. يُجرى الفحص وفق أعلى معايير الاعتماد الدولي وبإشراف نخبة من أطباء الأنف والأذن والحنجرة واستشاريي الوراثة السريرية في دولة الإمارات العربية المتحدة، مع ضمان خصوصية البيانات وفقاً لقانون حماية البيانات الشخصية الإماراتي.
- ✓Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- ✓Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy — 8 AM to 11 PM, 7 days a week.
- ✓Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance in result interpretation with a qualified genetic counselor.
- ✓Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Clinical Test Overview
The SLC26A4 Gene Pendred Syndrome Genetic Test is a comprehensive next-generation sequencing assay that analyzes the entire coding region of the SLC26A4 gene to detect pathogenic variants associated with Pendred syndrome — the most common syndromic cause of hereditary sensorineural hearing loss. يتم إجراء هذا التحليل الجيني المتقدم لتأكيد التشخيص السريري وتوجيه خطة التدخل السمعي والغُدّي للمريض وعائلته في دولة الإمارات.
| Parameter | Our Test — SLC26A4 NGS | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Diagnostic Precision | 99.9% Sensitivity — Full exon coverage via NGS | ~95% — Limited to known hotspots |
| Methodology | NGS (Next Generation Sequencing) with CNV analysis | Sanger Sequencing — no CNV detection |
| Turnaround Time | 3 to 4 Weeks | 4 to 6 Weeks |
Physician Insight & Safety Protocol
Clinical Note from Dr. Prabhakar Reddy (DHA License: 61713011):
"A positive SLC26A4 variant confirms Pendred syndrome and empowers your care team to implement early audiological intervention, thyroid surveillance, and informed reproductive counseling. Please remember that this genetic result must always be correlated with your complete audiological workup, thyroid function studies, and temporal bone imaging — a negative report does not exclude other genetic or acquired causes of hearing loss, and clinical follow-up remains essential."
⚠ Medication Warning:
Do not discontinue any prescribed medication — including thyroid hormone replacement (levothyroxine), diuretics, or any otologic therapy — without consulting your treating physician. Abrupt cessation may cause serious clinical deterioration.
🚨 Safety Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: This test is not indicated for individuals with isolated non-syndromic hearing loss without clinical or radiological suspicion of Pendred syndrome. A pre-test genetic counseling session is mandatory per UAE CDS Law 2026 for minors.
- ER Red Flags — Seek Immediate Medical Attention If: Sudden worsening or profound loss of hearing, acute neck swelling with breathing difficulty (possible goiter compression), or signs of severe hypothyroidism (myxedema, bradycardia, hypothermia).
- Pediatric Safeguard (CDS Law 2026): For minors, written informed consent from a legal guardian and a mandatory genetic counseling session are strictly required prior to sample collection. Testing without counseling is prohibited.
Patient FAQ & Clinical Guidance
What is the SLC26A4 gene test for Pendred syndrome, and why is NGS the preferred method?
The SLC26A4 NGS test comprehensively sequences the entire coding region of the pendrin gene to identify pathogenic variants causing Pendred syndrome with 99.9% diagnostic sensitivity. NGS is the preferred methodology because it captures all exonic mutations and copy number variations in a single assay, unlike Sanger sequencing which only targets predefined hotspots and may miss rare or novel variants prevalent in the genetically diverse UAE population.
How long does it take to receive results, and what does the 2800 AED fee include?
Results are delivered within 3 to 4 weeks and the 2800 AED fee includes ISO-certified cold-chain home sample collection, full NGS library preparation and sequencing, bioinformatic analysis, a comprehensive clinical report reviewed by a DHA-licensed genetic counselor, and one complimentary telephonic post-test consultation to guide your next clinical steps.
هل يمكن إجراء تحليل جين SLC26A4 للأطفال، وما هي المتطلبات القانونية في الإمارات؟
نعم، يمكن إجراء تحليل جين SLC26A4 للأطفال القُصَّر في دولة الإمارات العربية المتحدة، ولكن بشرط الحصول على موافقة خطية مستنيرة من ولي الأمر القانوني وإتمام جلسة استشارة وراثية إلزامية قبل سحب العينة، وذلك امتثالاً لأحكام قانون الخدمات السريرية التشخيصية لعام 2026 وقانون حماية البيانات الشخصية الإماراتي.
(Yes, the SLC26A4 gene test can be performed for minors in the UAE, provided written informed consent is obtained from the legal guardian and a mandatory genetic counseling session is completed prior to sample collection, in full compliance with CDS Law 2026 and UAE PDPL.)
UAE Regulatory Compliance & Accreditation
- Federal Decree-Law No. 41 of 2024 (Art. 87) — Medical Laboratory Standards
- CDS Law 2026 — Clinical Diagnostic Services Law (Mandatory Genetic Counseling for Minors)
- UAE PDPL — Personal Data Protection Law (Genetic Data Privacy)
- ISO 9001:2015 Certified — Cert: INT/EGQ/2509DA/3139
- DHA Facility License: 9834453
Book Your SLC26A4 Genetic Today
Home Collection | 3–4 Weeks TAT | 2800 AED | DHA-Licensed
WhatsApp: +971 54 548 8731Available 8 AM – 11 PM | 7 Days a Week
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