Test Price
2,800 AED✅ Home Collection Available
TMC1 Gene Deafness Autosomal Recessive Type 7 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين TMC1 للصمم الوراثي المتنحي النوع 7 بتقنية التسلسل الجيني من الجيل التالي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- 99.9% Diagnostic Sensitivity via ISO‑accredited Next‑Generation Sequencing.
- Premium Logistics: Paid hospital‑grade home collection with ISO‑certified cold‑chain handling and VIP mobile phlebotomy.
- Clinical Guidance: Complimentary telephonic post‑test result interpretation with our medical team.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
الملخص التنفيذي: دقة تشخيصية 99.9% عبر معالجة معتمدة ISO، جمع عينات منزلي فاخر، دعم واتساب، وإرشاد طبي مجاني.
Comprehensive TMC1 Gene Sequencing for Hereditary Deafness
The TMC1 (Transmembrane Channel‑Like 1) gene test uses Next‑Generation Sequencing (NGS) to detect autosomal recessive type 7 non‑syndromic hearing loss (DFNB7) with unparalleled accuracy. This analysis identifies pathogenic variants causative of prelingual, severe‑to‑profound sensorineural deafness, enabling early intervention and family planning.
يفحص تحليل جين TMC1 الطفرات المسببة للصمم الوراثي المتنحي النوع 7 بدقة فائقة عبر التسلسل الجيني المتقدم، ويدعم التشخيص المبكر والاستشارة الوراثية.
| Feature | Our TMC1 NGS Test | Closest Alternative (Single‑Gene Sanger) |
|---|---|---|
| Precision | 99.9% analytical sensitivity & specificity | ~95% sensitivity; may miss deep intronic/rearrangement variants |
| Methodology | Next‑Generation Sequencing (NGS) with full gene coverage & copy number analysis | Sanger sequencing of coding exons only |
| Turnaround | 3 to 4 Weeks | 4 to 6 Weeks |
| Clinical Depth | Includes MLPA/CNV detection for large deletions/duplications | Limited to point mutations & small indels |
| Genetic Counselling | Complimentary pre‑ & post‑test counselling (DHA‑licensed) | Often requires external referral |
Physician Insight & Safety Protocol
“Early genetic diagnosis of TMC1‑related deafness is life‑changing – it opens doors to timely cochlear implantation, tailored educational support, and informed reproductive decisions. However, a negative result does not exclude other hereditary or environmental causes; clinical correlation with audiological profiles is essential.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011, Clinical Geneticist & ENT Consultant
Medication Safety Notice
Do not discontinue any prescribed medication or alter treatment plans based solely on genetic test results. Always consult your treating physician.
Exclusion Criteria & ER Red Flags: This test is not a screening tool for auditory neuropathy, acquired hearing loss, or syndromic forms of deafness. Seek immediate medical attention if you experience sudden hearing loss, acute vertigo, ear trauma, or facial weakness. Test results must be interpreted alongside comprehensive audiological evaluation (ABR, OAE) and family history.
Patient FAQ & Clinical Guidance
What does the TMC1 Genetic Test detect and who should consider it?
The TMC1 NGS test identifies disease‑causing variants responsible for autosomal recessive non‑syndromic hearing loss type 7 (DFNB7), typically presenting as severe‑to‑profound prelingual deafness, and is recommended for individuals with congenital or early‑onset bilateral sensorineural hearing loss, especially when family history suggests recessive inheritance.
يكشف تحليل TMC1 بتقنية NGS عن الطفرات المسببة للصمم الوراثي المتنحي النوع 7 وهو موصى به للمرضى المصابين بفقدان سمع حسي عصبي ثنائي الجانب منذ الولادة أو الطفولة المبكرة.
How is the sample collected and what are the preparation requirements?
A single blood draw, extracted DNA, or a dried blood spot on an FTA card is collected by our DHA‑licensed phlebotomists during a hospital‑grade home visit; no fasting or medication changes are required, though a prior genetic counselling session is strongly advised to ensure appropriate test selection and family pedigree documentation.
يتم جمع عينة دم وريدي أو بقعة دم جافة على بطاقة FTA بواسطة ممرضين مرخصين في منزلك دون الحاجة لصيام، مع جلسة استشارة وراثية مسبقة.
What happens after I receive my results and how are they protected under UAE law?
Your NGS report, compliant with UAE Federal Decree‑Law No. 41 of 2024 and PDPL, is delivered securely via encrypted channels, and a licensed genetic counsellor provides a complimentary telephonic session to interpret findings, discuss recurrence risks, and guide next clinical steps, while health data remains strictly confidential.
تُسلَّم النتائج بسرية تامة وفقاً للمرسوم بقانون اتحادي رقم 41 لسنة 2024 وقانون حماية البيانات الشخصية، مع جلسة إرشاد وراثي هاتفية مجانية لتفسير التقرير.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians