Test Price
2,800 AED✅ Home Collection Available
GSDME (DFNA5) Gene NGS Sequencing for Autosomal Dominant Deafness Type 5 in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل جين GSDME (DFNA5) للصمم الوراثي السائد | 2800 درهم | إرشادات هيئة الصحة بدبي 2026
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي: يوفر هذا الفحص الجيني المتطور لتقصي طفرات جين GSDME دقة تشخيصية تصل إلى 99.9% من خلال مختبرات حاصلة على شهادة ISO 9001:2015 ومرخصة من هيئة الصحة بدبي، مع خدمة سحب منزلي وباستشارة طبية ما بعد الفحص. الفحص معتمد وفق القانون الاتحادي رقم 41 لسنة 2024 وقانون حماية البيانات الشخصية.
Clinical Overview & Test Comparison
The GSDME (DFNA5) gene NGS test screens for pathogenic variants causing autosomal dominant non-syndromic hearing loss (DFNA5), providing a definitive molecular diagnosis for hereditary deafness. يُستخدم هذا التحليل لتحديد الطفرات المسببة للصمم الوراثي النمط الخامس بدقة عالية باستخدام التقنيات الجزيئية.
| Feature | Our GSDME NGS Test | Closest Alternative (Single-Gene Sanger) |
|---|---|---|
| Precision | 99.9% Analytical Sensitivity & Specificity | 95–98% for targeted regions |
| Method | Next-Generation Sequencing (NGS) + Sanger Confirmation | Conventional Sanger Sequencing |
| Turnaround Time | 3 to 4 Weeks | 6–8 Weeks |
| Coverage | Full coding region & splice sites | Sequential exon-by-exon |
Physician Insight & Safety Protocol
“Understanding your genetic hearing loss is a deeply personal journey. We combine advanced NGS technology with compassionate clinical correlation to ensure every result is interpreted in the context of your family history and audiological profile. Please remember that this test is a tool for diagnosis but does not replace a complete ENT and genetics consultation.”
— Dr. PRABHAKAR REDDY, DHA License: 61713011
⚠ Medication Warning
Do not discontinue any prescribed medication without consulting your physician. This genetic test does not provide immediate therapeutic advice.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: This test is not intended for prenatal diagnosis without prior genetic counselling. It should not be used as the sole investigation in non-genetic hearing loss (e.g., ototoxic drug exposure, acute noise trauma) unless a hereditary component is strongly suspected.
- Emergency Red Flags: If you experience sudden hearing loss, severe vertigo, facial weakness, or tinnitus, seek immediate emergency care. These symptoms may indicate acute otologic emergencies unrelated to genetic testing.
- Minors require consent in accordance with UAE Federal Decree-Law No. 41 of 2024 and CDS Law 2026.
Patient FAQ & Clinical Guidance
1. What is the GSDME (DFNA5) gene deafness test and who should consider it?
This NGS-based test identifies mutations in the GSDME gene responsible for autosomal dominant non-syndromic hearing loss, aiding early diagnosis and family planning. It is recommended for individuals with progressive sensorineural hearing loss and a strong family history of deafness, as well as for asymptomatic at-risk relatives seeking clarity.
هذا الاختبار الجيني يحدد الطفرات المسببة للصمم الوراثي السائد من النوع الخامس بدقة عالية، ويُوصى به للمرضى الذين يعانون من فقدان سمع حسي عصبي تقدمي ولديهم تاريخ عائلي للإصابة.
2. How accurate is this genetic and what is the turnaround time?
With over 99.9% diagnostic sensitivity and confirmation via Sanger sequencing, results are provided within 3 to 4 weeks from sample receipt. Our ISO-certified laboratory uses the latest NGS technology and data analysis pipelines aligned with 2026 DHA standards, ensuring reliable variant interpretation.
تبلغ حساسية التشخيص 99.9% مع تأكيد عبر تقنية سانجر، وتُسلّم النتائج خلال 3 إلى 4 أسابيع عبر مختبر معتمد من هيئة الصحة بدبي.
3. Are there any special preparation steps or risks associated with sample collection?
No fasting or medication adjustments are needed; a simple blood draw or DNA sample is collected by our certified phlebotomists without significant risk. The procedure is painless and takes only a few minutes; you can resume daily activities immediately. For infants, a one-drop blood spot on an FTA card is acceptable.
لا يتطلب الفحص صياماً أو تعديلاً للأدوية؛ تُجمع العينة بطريقة آمنة على يد فريق تمريض متخصص ومعتمد، ويمكن للمريض مغادرة المنزل فوراً.
Federal Decree-Law No. 41 of 2024 (Art. 87) | UAE PDPL Compliant | ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) | DHA Facility License: 9834453
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians