Test Price
2,800 AED✅ Home Collection Available
ESRRB Gene Deafness (Autosomal Recessive Type 35) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
✅ Accuracy Guarantee
99.9% Diagnostic Sensitivity via ISO 9001:2015‑accredited laboratory processing.
🚚 Premium Logistics
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
🩺 Clinical Guidance
Post‑test tele‑consultation for interpretation of results with a clinical genetic specialist.
📋 Insurance
Direct billing verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The ESRRB Gene NGS Test identifies pathogenic variants in the ESRRB gene responsible for autosomal recessive deafness type 35 (DFNB35). This enables precise diagnosis, familial risk assessment, and tailored auditory rehabilitation. The test employs targeted next‑generation sequencing (NGS) of all coding exons and flanking intronic regions of the ESRRB gene, offering a molecular solution when conventional audiometry does not reveal etiology.
| Feature | Our Test (ESRRB NGS) | Closest Alternative (Conventional Audiometry) |
|---|---|---|
| Diagnostic Focus | Genetic cause of deafness (ESRRB mutations) | Hearing threshold measurement only |
| Technology | Targeted Next‑Generation Sequencing (NGS) | Audiometer‑based pure tone testing |
| Turnaround Time | 3‑4 weeks | Same day (interpretation only) |
| Clinical Utility | Confirms hereditary diagnosis, cascade screening, reproductive planning | Identifies hearing loss type/severity, does not reveal etiology |
| Cost (AED) | 2800 | Varies (typically 300‑600) |
Pre‑Test Requirements & Logistics
- No fasting, medication hold, or special preparation required.
- A genetic counselling session is advised prior to testing to draw a detailed family pedigree.
- Accepted sample types: whole blood (venipuncture), extracted DNA, or a single drop of blood on an FTA card.
- Home collection appointment will be coordinated within your preferred 8 AM‑11 PM window.
Commonly Ordered By (Clinical Intent)
Physician Insight & Safety Protocols
“This ESRRB gene test provides a definitive molecular diagnosis for families affected by autosomal recessive deafness type 35. It is a powerful tool that should always be correlated with a full audiologic evaluation and clinical history. A genetic counselling session is essential before and after testing to interpret results and assess recurrence risks for future pregnancies. Any sudden or rapidly progressive hearing loss warrants immediate clinical evaluation irrespective of genetic findings.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA Registration ID: 9294403)
Medication Advisory
⚠️ Do not discontinue any prescribed medications or hearing aids without consulting your treating physician. Genetic test results do not alter existing medication regimens unless explicitly discussed during your consultation.
Exclusion Criteria & Emergency Red Flags
- Exclusion: The test cannot be interpreted in isolation; a clinical genetics consultation is mandatory for variant classification.
- Red Flag: Sudden or rapidly progressing hearing loss within 72 hours – seek ENT evaluation.
- Red Flag: Severe tinnitus with vertigo or loss of balance requiring same‑day ENT assessment.
- Red Flag: Associated neurological deficits (facial weakness, ataxia) – urgent neurological review.
Patient FAQ & Clinical Guidance
1. What is the ESRRB gene test and who should consider it?
This advanced genetic test analyzes the ESRRB gene to confirm autosomal recessive deafness type 35 (DFNB35). It is recommended for individuals with congenital or early‑onset non‑syndromic sensorineural hearing loss, especially when family history suggests recessive inheritance, and for relatives seeking carrier status for reproductive planning.
2. How is the sample collected and is home collection included?
A simple blood draw or a finger‑prick drop on an FTA card is collected by a DHA‑licensed phlebotomist during a scheduled home visit. No fasting is required. Your 2800 AED fee already includes VIP Mobile Phlebotomy and temperature‑controlled cold‑chain transport, available daily from 8 AM to 11 PM.
3. Are the results recognized by UAE health authorities and can I share them abroad?
Yes, the report is issued under DHA‑licensed facility (No. 1143) and ISO 9001:2015 accreditation, in full compliance with UAE Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the use of ICT in health fields. The report follows LOINC 97163‑3 coding, making it interoperable with international medical records.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143. All genetic testing services comply with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent are governed by Federal Decree‑Law No. 4 of 2016 on Medical Liability. Your genomic data remains confidential and is used solely for diagnostic purposes with your explicit consent.
Clinical & Logistical Metadata
| Test Name | ESRRB Gene Deafness (Autosomal Recessive Type 35) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card (dried blood spot) |
| Methodology Used | Targeted Next‑Generation Sequencing (NGS) of coding exons and flanking intronic regions |
| ICD-10-CM Code | H90.3 (Bilateral sensorineural hearing loss) |
| LOINC Code | 97163-3 (Genetic test for hearing loss) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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