Test Price
2,800 AEDโ Home Collection Available
ZBTB24 Gene ICF Syndrome Type 2 Genetic Testing in UAE | AED 2800
Executive Summary & Core Metrics
โ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
โ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AMโ11 PM).
โ Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation by a DHA-licensed genetic specialist.
โ Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
The ZBTB24 gene test uses next-generation sequencing to diagnose Immunodeficiency-Centromeric Instability-Facial Anomalies (ICF) Syndrome Type 2, a rare primary immunodeficiency presenting with recurrent infections, characteristic facial dysmorphisms, and chromosomal instability. This test is essential for confirming the molecular diagnosis and guiding personalized clinical management in both pediatric and adult patients in the UAE.
| Feature | Our Test (DNA Labs UAE) | Closest Alternative (Other UAE Labs) |
|---|---|---|
| Methodology | NGS (Full Coding Region + Splice Sites) | Sanger Sequencing (limited to known hotspots) |
| Diagnostic Sensitivity | >99.9% for SNVs/indels | ~95% (misses rare variants) |
| Turnaround Time | 3 โ 4 Weeks | 4 โ 6 Weeks |
| Cost | AED 2800 (all-inclusive) | AED 2800 โ 3500 |
Physician Insight & Safety Protocols
โThe ZBTB24 NGS test must be correlated with a comprehensive clinical evaluation and family pedigree. A negative result does not rule out other genetic causes of ICF-like phenotypes, and genetic counselling remains essential before and after testing. Always interpret findings alongside immunological and dysmorphology assessments.โ โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory for Patients
โ ๏ธ Important Warnings
Do not discontinue or alter any prescribed medication (e.g., immunoglobulin therapy, prophylactic antibiotics) without direct consultation with your treating physician. This test provides diagnostic information but does not replace ongoing medical management.
Emergency red flags: If the patient develops severe respiratory distress, high fever with neutropenia, or acute neurological changes, seek immediate medical attention at the nearest UAE hospitalโdo not wait for test results.
Informed consent is mandatory per Federal Decree-Law No. 4 of 2016 on Medical Liability. A genetic counselling session is required before sample collection.
Exclusion Criteria
Patients with an established molecular diagnosis for ICF syndrome (unless confirmation needed), recent bone marrow transplant (<3 months), or inability to provide informed consent are not eligible for this test. Please discuss alternative diagnostic pathways with your physician.
Patient FAQ & Clinical Guidance
1. What exactly does the ZBTB24 gene test detect?
This NGS test detects ZBTB24 gene mutations causing ICF syndrome type 2, a rare primary immunodeficiency. It analyzes the entire coding region for single nucleotide variants, small insertions/deletions, and splice-site alterations, providing a definitive molecular diagnosis when clinical features and immunological markers are suggestive.
2. Who should consider this genetic test?
Patients with recurrent infections, facial dysmorphism, and suspected ICF syndrome should undergo ZBTB24 NGS testing. Appropriate candidates include neonates with low immunoglobulins, children with characteristic facial features (hypertelorism, epicanthal folds, flat nasal bridge), and adults with unexplained combined immunodeficiency. A pre-test genetic counselling session is mandatory to assess family history and obtain informed consent.
3. How is the sample collected and when will I get the results?
A simple blood draw is collected via our VIP Mobile Phlebotomy service, available daily from 8 AM to 11 PM across all emirates. Samples are transported in ISO-certified cold-chain containers to our molecular genetics lab. Results are ready in 3โ4 weeks. You will be telephonically notified when the report is ready, followed by a post-test clinical guidance session with a genetic specialist.
UAE Regulatory & Data Privacy Adherence
Compliance & Data Protection
This genetic test is performed in strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Our laboratory holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and is DHA-licensed under facility number #1143. All test results are encrypted and accessible only to the patient and their designated healthcare providers.
Clinical & Logistical Metadata
| Test Name | ZBTB24 Gene โ ICF Syndrome Type 2 Genetic Testing (NGS) |
| Price (AED) | AED 2,800 (All-Inclusive) |
| Turnaround Time | 3 โ 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA or FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) โ Full Coding Region & Splice Sites |
| ICD-10-CM Code | D81.8 (Other combined immunodeficiencies) |
| LOINC Code | 92747-3 (ZBTB24 gene targeted mutation analysis in Blood by NGS) |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians