Test Price
2,800 AED✅ Home Collection Available
TTR Gene Amyloidosis Genetic Test (NGS) – 2,800 AED
Executive Summary & Core Metrics
Comprehensive next-generation sequencing for hereditary transthyretin (ATTR) amyloidosis with 99.9% diagnostic sensitivity.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM)
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
This advanced NGS panel empowers neurologists, cardiologists, and geneticists to confirm hereditary ATTR amyloidosis, guide therapeutic decisions, and screen at-risk relatives. The test provides full coverage of the TTR gene coding exons and splice junctions.
| Parameter | Our Test (NGS) | Competitor IHC/Biopsy |
|---|---|---|
| Precision | 99.9% sensitivity for all known TTR variants | Variable; may miss rare mutations |
| Methodology | NGS with full gene coverage | Immunohistochemistry (limited specificity) |
| Turnaround Time | 3–4 Weeks | Results often non-diagnostic |
Physician Insight & Safety Protocols
“As a consultant medical geneticist, I witness the transformative power of early genetic diagnosis in ATTR patients. This NGS test provides definitive molecular clarity, enabling timely interventions that preserve quality of life. I strongly advise correlating molecular results with a comprehensive clinical evaluation and family pedigree analysis. Genetic counselling is essential before and after testing.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Pre-Test Advisory
- Do not discontinue any prescribed medication without consulting your treating physician. Genetic test results should guide, not replace, clinical management.
- Prior genetic counselling is mandatory for all patients and asymptomatic relatives to ensure informed consent and understanding of implications.
- Results may identify variants of uncertain significance (VUS) that require further family segregation studies.
Exclusion Criteria & Emergency Red Flags
- Patients with acute illness or unstable conditions (e.g., uncontrolled heart failure) are excluded from home phlebotomy; hospital-based collection is required.
- If you experience severe neuropathy, dysautonomia, or cardiac arrhythmias prior to testing, seek immediate emergency care.
- This test is not intended for asymptomatic minors without prior genetics consultation and written informed consent as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
Patient FAQ & Clinical Guidance
1. What is the detection rate of this TTR gene test for hereditary amyloidosis?
With next-generation sequencing, our test detects over 99% of pathogenic TTR variants, delivering a definitive molecular diagnosis in hereditary ATTR amyloidosis. This NGS panel covers all coding exons and splice sites, ensuring even rare mutations are not missed.
2. How do I prepare for the blood sample collection at home?
No fasting is required; our certified phlebotomist arrives with a cold-chain transport kit, collecting a single 3–5 mL EDTA whole blood sample. A prior genetic counselling session is mandatory to document the pedigree chart, as per DHA norms. Please avoid strenuous exercise 2 hours before.
3. Can this test be used for predictive screening of family members?
This genetic test identifies asymptomatic carriers among relatives of a confirmed ATTR patient, enabling early surveillance and prophylactic management. UAE regulations require written informed consent and post-genetic counselling for all predictive screenings.
UAE Regulatory & Data Privacy Adherence
- All patient data handling complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Clinical testing safety and patient consent protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
- DNA Labs UAE is fully licensed by the Dubai Health Authority (DHA) under facility license number 1143, operating in Dubai Healthcare City.
Clinical & Logistical Metadata
| Test Name | TTR Gene Amyloidosis Genetic Test (NGS) – Hereditary Transthyretin Amyloidosis |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) – 3–5 mL |
| Methodology Used | Next-Generation Sequencing (NGS) – Full gene coverage of TTR coding exons and splice sites |
| ICD-10-CM Code | E85.2 (Hereditary amyloidosis) |
| LOINC Code | 82939-0 (TTR gene mutation analysis in Blood) |
| DHA Facility License & Laboratory Address | 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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