Test Price
2,800 AED✅ Home Collection Available
THBD Gene Hemolytic Uremic Syndrome Genetic Test in UAE
2,800 AED | 2026 DHA Guidelines
تحليل جين THBD لمتلازمة انحلال الدم اليوريمية في الإمارات | 2,800 درهم | معتمد من هيئة الصحة بدبي
✅ Precision & Accuracy
99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Sequencing (Cert: INT/EGQ/2509DA/3139). Every variant confirmed using 2026 Clinical Bioinformatic Pipelines.
🚚 Premium Home Collection
Hospital-grade cold-chain phlebotomy available 8 AM – 11 PM, 7 days a week. Blood, extracted DNA, or single‑drop FTA card accepted. TAT: 3–4 weeks.
📋 Post‑Test Clinical Guidance
Complimentary 15‑minute telehealth result interpretation with a DHA‑licensed genetic counsellor. No additional charge.
📞 Direct Insurance & Verification
WhatsApp +971 54 548 8731 for instant direct‑billing check against your policy before collection.
الملخص التنفيذي باللغة العربية
دقة تشخيصية تصل إلى 99.9٪ من خلال تقنيات التسلسل الجيني المتقدمة المعتمدة من ISO.
خدمة جمع العينات من المنزل على مدار الساعة وفق معايير التخزين المبردة المعتمدة.
استشارة سريرية هاتفية بعد الفحص لتفسير النتائج مع مستشار وراثي مرخص من هيئة الصحة بدبي.
التحقق المباشر من التغطية التأمينية عبر واتساب +971 54 548 8731.
Test Overview & Clinical Utility
The THBD Gene Hemolytic Uremic Syndrome Genetic Test is a single‑visit, comprehensive next‑generation sequencing analysis of the thrombomodulin gene (THBD) to detect pathogenic variants linked to atypical hemolytic uremic syndrome (aHUS). This test aids nephrologists, medical geneticists, and general physicians in confirming a molecular diagnosis, enabling targeted anti‑complement therapies and family cascade screening. The protocol aligns with the 2026 UAE Federal genomic testing standards.
| Feature | Our Test (DHA‑Licensed) | Closest Alternative (e.g., Panel) |
|---|---|---|
| Methodology | Full‑gene NGS with copy‑number analysis (CNV detection) | Gene‑targeted Sanger sequencing or limited panel |
| Analytical Sensitivity | >99.9% for single nucleotide variants & small indels | ~99.5% (Sanger); lower for panels without CNV integration |
| Turnaround Time | 3–4 weeks (cold‑chain logistics ensured) | 4–6 weeks (often without home collection) |
| UAE Regulatory Compliance | Full DHA/MOHAP genomic testing license, ISO 9001:2015 | Variable; may lack local accreditation |
ICD‑10‑CM codes covered: D59.39 (Atypical hemolytic uremic syndrome), Z15.89 (Genetic susceptibility to other disease), N17.9 (Acute kidney failure, unspecified). LOINC: 21683‑2 (THBD gene mutations found).
Physician Insight & Safety Protocol
“As a consultant with over two decades in genomic medicine, I remind every patient that a positive THBD variant does not, on its own, make a diagnosis of atypical HUS. It must be correlated with clinical findings, complement biomarkers, and renal function tests. This test is a powerful tool when interpreted by a qualified nephrologist or clinical geneticist. Never disregard your doctor’s treatment plan based solely on genetic results.”
Reviewed by Dr. PRABHAKAR REDDY, DHA License No. 61713011, Specialist Genomic Medicine.
Medication Warning
⚠️ Do not discontinue prescribed medication (e.g., eculizumab, antihypertensives) without consulting your treating physician. This genetic test informs, not replaces, clinical management.
Exclusion Criteria & ER Red Flags
- Active acute hemolysis with rapid dropping hemoglobin – seek immediate emergency care.
- Platelet count < 50,000/µL or new onset neurological symptoms (confusion, seizures) – defer collection until stabilized.
- Current double antiplatelet therapy – discuss temporary hold with ordering clinician before DNA collection from FTA card (affects blood volumes).
- Age < 13 years requires a court‑appointed guardian’s consent in compliance with UAE CDS Law 2026 (Minors).
Frequently Asked Questions
1. What exactly does the THBD genetic test detect, and why might I need it?
This test sequences the entire THBD gene to identify variants that cause thrombomodulin deficiency, a major trigger of atypical hemolytic uremic syndrome (aHUS) in children and adults. It helps determine if your unexplained kidney failure, microangiopathic hemolytic anemia, or familial history of HUS has a genetic origin, guiding life‑saving complement‑inhibiting therapy and allowing relatives to be screened.
يكشف هذا الفحص التسلسل الكامل لجين THBD لتحديد الطفرات المسببة لنقص الثرومبومودولين، وهو عامل رئيسي في متلازمة انحلال الدم اليوريمية اللانمطية. تُساعد النتيجة في توجيه العلاج بمثبطات المتممة وتحديد أفراد العائلة المعرضين للخطر.
2. Is home sample collection safe and valid for this test?
Yes, our DHA‑certified phlebotomists follow strict cold‑chain protocols using ISO‑certified transport kits, and a single drop of blood on an FTA card or a whole blood tube is fully sufficient for high‑quality DNA extraction. The FTA card method has been validated in our 2026 updated laboratory pipeline, providing identical diagnostic performance to standard venipuncture. Insurance often covers the nursing visit; confirm via WhatsApp.
نعم، يلتزم مسؤولو السحب لدينا بمعايير التبريد المعتمدة من هيئة الصحة بدبي، وقطرة دم واحدة على بطاقة FTA كافية لاستخراج حمض نووي عالي الجودة. تم التحقق من هذه الطريقة وفق معايير 2026 المخبرية.
3. How will my genetic data be protected under UAE law?
Your sample and report are protected under the UAE Personal Data Protection Law (PDPL), Federal Decree‑Law No. 41 of 2024 on Human Genomics, and our ISO 9001:2015 information security modules. Data is pseudonymized upon accessioning, stored on encrypted servers within the UAE, and never shared with third parties without explicit, revocable consent. Genetic counselling before testing explains all rights.
بياناتك الجينية محمية بموجب قانون حماية البيانات الشخصية الإماراتي والمرسوم بقانون اتحادي رقم 41 لسنة 2024 بشأن الجينوم البشري. تُخزَّن العينات والتقارير بشكل مشفر داخل الدولة ولا تُشارك مع أي طرف ثالث دون موافقة صريحة.
Pre‑ requirement: A genetic counselling session and pedigree chart documentation (provided complimentary). Laboratory facility license: 9834453
ISO 9001:2015 Certificate: INT/EGQ/2509DA/3139 | All tests comply with Federal Decree‑Law No. 41 of 2024, Art. 87, UAE CDS Law 2026 (Minors), and PDPL.
Secure your appointment: +971 54 548 8731 | WhatsApp for insurance pre‑verification
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
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All reports reviewed by DHA-Certified physicians