Test Price
2,800 AED✅ Home Collection Available
SP110 Gene Hepatic Veno-Occlusive Disease with Immunodeficiency Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين SP110 لمرض الانسداد الوريدي الكبدي مع نقص المناعة في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 accredited NGS processing, ensuring exhaustive coverage of the SP110 gene.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Complimentary Telephonic Post-Test Clinical Guidance in result interpretation with a DHA-licensed clinical specialist.
- Insurance: Direct Billing Verification available via WhatsApp at +971 54 548 8731.
Test Overview
The SP110 Gene Hepatic Veno-Occlusive Disease with Immunodeficiency (VODI) NGS Test screens for pathogenic variants in the entire coding region of SP110 using Next‑Generation Sequencing. This advanced assay aids in diagnosing a rare combined immunodeficiency syndrome that predisposes individuals to hepatic veno‑occlusive disease and severe infections, enabling timely clinical intervention. يساعد هذا التحليل الجيني المتقدم في تشخيص نقص المناعة المشترك النادر المرتبط بمرض الانسداد الوريدي الكبدي.
| Feature | Our Test (ISO‑Accredited) | Closest Alternative (Standard Panel) |
|---|---|---|
| Precision | Full gene sequencing & copy number analysis via NGS; >99.9% analytical sensitivity | Partial coverage / hotspot genotyping; ~93–97% sensitivity |
| Method | Next‑Generation Sequencing (Illumina NovaSeq) with Sanger validation | Targeted mutation panels or single‑exon Sanger |
| Turnaround | 3 to 4 Weeks (ISO 9001:2015 certified lab) | 4 to 8 Weeks (non‑prioritized) |
Physician Insight & Safety Protocol
Note from Dr. Prabhakar Reddy (DHA License 61713011): “A positive SP110 result must be correlated with clinical hepatological and immunological findings. Genetic counselling is essential before and after testing, as VODI follows an autosomal recessive pattern and may necessitate family screening. False reassurance can arise from a negative result if a deep intronic or regulatory variant is not captured; continue monitoring if symptoms persist.”
‼ Medication Safety Warning
Do not discontinue, adjust, or withhold any prescribed immunosuppressants, anticoagulants, or hepatoprotective medication without consulting your treating physician. Sudden cessation can provoke acute liver decompensation or profound immunodeficiency.
Exclusion Criteria & Emergency Red Flags
- Do not undergo testing if you have an active febrile illness or acute liver failure requiring hospitalization.
- Requires immediate DHA emergency room visit if you experience: acute onset of ascites, jaundice, unexplained high fever >39°C, or sudden hypoxia.
- Post-test: If you develop signs of portal hypertension (hematemesis, melena, abdominal distention) contact your hepatologist urgently.
Patient FAQ & Clinical Guidance
1. What exactly does the SP110 gene test detect, and why is it ordered?
Direct Answer: This NGS test identifies disease‑causing mutations in the SP110 gene that cause hepatic veno‑occlusive disease with immunodeficiency (VODI), a severe inherited disorder combining liver vein blockage and immune system failure. يكشف هذا الاختبار الطفرات المسببة لمرض الانسداد الوريدي الكبدي مع نقص المناعة.
2. How is the sample collected, and is home service available in Dubai and Abu Dhabi?
Direct Answer: We accept venous blood, extracted DNA, or a single drop of blood on an FTA card, collected by a DHA‑licensed phlebotomist during our premium home visit from 8 AM to 11 PM across all Emirates. نقبل عينة دم وريدي أو حمض نووي مستخلص أو قطرة دم واحدة على بطاقة FTA.
3. Why does the take 3 to 4 weeks, and what happens after I receive the result?
Direct Answer: The exhaustive library preparation, sequencing, and multidisciplinary clinical annotation require 3–4 weeks; you then receive a comprehensive report and a tele‑counselling session with a genetic specialist to interpret the findings. يستغرق التحليل 3-4 أسابيع، ثم يتم تقديم جلسة استشارة وراثية هاتفية لشرح النتائج.
This laboratory service is provided in strict accordance with UAE Federal Decree-Law No. 41 of 2024 (Article 87), the Child Data Sovereignty Law 2026 for minors, and the UAE Personal Data Protection Law (PDPL). All genetic counselling adheres to DHA-MOHAP guidelines. ISO 9001:2015 Certification: INT/EGQ/2509DA/3139. Facility License: 9834453.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians