Test Price
2,800 AEDโ Home Collection Available
SNCA Gene Dementia & Lewy Body Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Test Overview & Methodology
The SNCA Gene Dementia & Lewy Body Genetic Test uses Next-Generation Sequencing (NGS) to analyse the entire SNCA gene for pathogenic variants associated with ฮฑ-synuclein aggregation, the hallmark of Lewy body dementia and Parkinsonโs disease dementia. This advanced test helps neurologists confirm a genetic predisposition, guiding personalised care planning and family counselling.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | >99.9% single-nucleotide variant detection | ~95% with older Sanger-based panels |
| Method | NGS (Next-Generation Sequencing) full gene coverage | Limited hotspot analysis |
| Speed | Results in 3โ4 weeks with DHA-compliant reporting | 4โ6 weeks, often no clinical interpretation |
| Sample Options | Whole blood, extracted DNA, or dry blood spot (FTA card) | Blood only |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh (Consultant Medical Genetics, DHA: 9294403)
โA positive SNCA variant is not a diagnosis of dementia; it reveals susceptibility. I recommend this test when a patient presents with progressive cognitive decline, visual hallucinations, or parkinsonism with a strong family history. The genetic insight helps us risk-stratify family members and initiate early protective interventions, but must always be correlated with clinical and imaging findings.โ
Advisory Notice
Do not discontinue any prescribed medication without consulting your doctor. Genetic testing does not replace ongoing therapy for movement or cognitive symptoms. Always inform your neurologist and primary care physician before making any changes.
Exclusion Criteria & Emergency Red Flags
- Minors (under 18) require legal guardian consent per Federal Decree-Law No. 2 of 2019 concerning the Use of Information and Communication Technology in Health Fields.
- Inability to provide informed consent necessitates a legally authorised representative.
- Recent head trauma or acute stroke symptoms (sudden weakness, speech loss) โ proceed to ER immediately.
- Uncontrolled seizures or rapid neurological deterioration โ seek emergency care before sample collection.
- This test is not for whole genome screening and does not detect all causes of dementia.
Patient FAQ & Clinical Guidance
1. What exactly does the SNCA NGS test detect, and why is it important?
This test sequences the SNCA gene to identify inherited mutations that increase the risk of Lewy body dementia and related synucleinopathies. Early detection allows neurologists to tailor surveillance, lifestyle modifications, and family screening, potentially delaying onset or severity of symptoms.
2. How is the sample collected, and can I do it at home?
A small blood sample (or dry blood spot) is collected by our DHA-licensed mobile phlebotomist at your home, office, or hospital. The sample is transported in a certified cold-chain kit to our ISO 9001:2015 molecular lab, ensuring stability for high-quality DNA extraction and NGS analysis.
3. When will I receive the results and how will they be explained?
Turnaround time is 3 to 4 weeks. You will receive a secure DHA-compliant report, and a consultant medical geneticist will conduct a telephonic post-test consultation to interpret the findings, discuss clinical implications, and recommend next stepsโall at no extra cost.
UAE Regulatory & Data Privacy Adherence
Data Privacy & Security: All genetic data is processed in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the Use of Information and Communication Technology in Health Fields. Patient consent and safety are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Accreditations: ISO 9001:2015 certified (Cert: INT/EGQ/2509DA/3139). DHA Facility License No. 1143 issued by Dubai Healthcare City.
For insurance verification, home collection booking, or clinical questions, WhatsApp: +971 54 548 8731
Clinical & Logistical Metadata
| Test Name | SNCA Gene Dementia & Lewy Body Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 weeks (21โ28 days) |
| Sample Type / Matrix | Whole blood, extracted DNA, or dry blood spot (FTA card). VIP Mobile Phlebotomy available daily 8 AMโ11 PM. |
| Methodology Used | Next-Generation Sequencing (NGS) โ full gene coverage |
| ICD-10-CM Code | G31.84 (Lewy body disease) |
| LOINC Code | 73518-2 (SNCA gene full sequencing) |
| DHA Facility License & Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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All reports reviewed by DHA-Certified physicians