Test Price
2,800 AEDโ Home Collection Available
SLURP1 Gene Mal de Meleda Genetic Test in UAE | 2800 AED | DHA Licensed Laboratory
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity โ ISO 9001:2015 Accredited
This targeted next-generation sequencing (NGS) test analyses the SLURP1 gene for pathogenic variants causing Mal de Meleda. It is performed on a peripheral whole blood sample with temperature-controlled home collection available daily. Turnaround time is 3โ4 weeks, including a post-result clinical guidance call with a genetics specialist.
Price: 2800 AED โ includes genetic counselling and digital report. DHA Facility License: 1143, Dubai Healthcare City.
Test Overview & Methodology
The SLURP1 gene Mal de Meleda genetic test uses Next-Generation Sequencing (NGS) to detect disease-causing mutations in coding exons and flanking regions. This provides high-resolution diagnostic confirmation for autosomal recessive palmoplantar keratoderma, enabling accurate genetic counselling and familial risk assessment.
| Feature | Our Test (NGS) | Closest Alternative (Sanger) |
|---|---|---|
| Detection Rate | >99% variants (coding exons + flanking regions) | Limited to known hotspot regions |
| Turnaround Time | 3โ4 weeks with digital report | 4โ6 weeks, manual interpretation |
| Cost in UAE | 2800 AED | Often 3500+ AED without genetic counselling |
Physician Insight & Safety Protocols
โIdentification of a pathogenic SLURP1 variant confirms Mal de Meleda definitively; however, full dermatological and genetic evaluation is essential for accurate prognosis and management. This test empowers families with actionable knowledge when integrated with clinical findings.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Safety Protocols & Advisory
Medication Advisory
Do not discontinue any prescribed treatments without consulting your dermatologist. Genetic testing complements, not replaces, current clinical management.
Pre-test requirement: A detailed clinical history and genetic counselling session to map family pedigree must be completed prior to sample collection.
Exclusion Criteria & Emergency Red Flags
- Allogeneic haematopoietic stem cell transplant within the last 6 months (chimerism may obscure germline DNA).
- Active infection at the blood draw site.
- Known severe allergy to chlorhexidine or iodine-based antiseptics.
Emergency Red Flags
- Excessive bleeding, rapid swelling, or signs of infection at the puncture site.
- New onset of widespread skin blistering or systemic illness unrelated to the underlying condition.
Patient FAQ & Clinical Guidance
1. What is the SLURP1 gene Mal de Meleda test?
This genetic test analyses the SLURP1 gene via next-generation sequencing to identify pathogenic variants causing Mal de Meleda, a rare autosomal recessive palmoplantar keratoderma. Results help dermatologists and geneticists confirm the condition, guide management, and evaluate family risk.
2. How do I prepare for the test?
No fasting is required. You can schedule a home collection visit; a genetic counsellor will contact you to record your medical and family history. Avoid blood-thinning medications unless approved by your physician. Sample collection uses standard venipuncture.
3. Is this test approved by UAE health authorities?
Yes, the laboratory holds DHA Facility License No. 1143, ISO 9001:2015 certification, and complies with UAE genetic service regulations. All results are confidential, with encrypted data storage compliant with local privacy laws.
UAE Regulatory & Data Privacy Adherence
Full Compliance with UAE Legislation
This service operates under DHA Facility License No. 1143 and adheres to:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) โ ensuring patient genetic data privacy.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields โ regulating secure health data handling.
- Federal Decree-Law No. 4 of 2016 on Medical Liability โ governing clinical testing safety and patient consent.
ISO 9001:2015 quality management system is maintained throughout sample processing and reporting.
Clinical & Logistical Metadata
| Test Name | SLURP1 Gene Mal de Meleda Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 weeks (21โ28 business days) |
| Sample Type / Matrix | Peripheral Whole Blood (standard venipuncture) |
| Methodology Used | Next-Generation Sequencing (NGS) โ coding exons and flanking regions |
| ICD-10-CM Code | Q82.8 |
| LOINC Code | 21637-4 |
| DHA Facility License & Laboratory Address | License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
ุฏุนู ุซูุงุฆู ุงููุบุฉ ู ุชุงุญ
ุงูุชุญูู ู ู ุงูุชุบุทูุฉ ุงูุชุฃู ูููุฉ
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
ุชููู ุนู ุงูุชุฎู ูู. ุฃุฑุณู ุตูุฑุฉ ู ู ุจุทุงูุฉ ุงูุชุฃู ูู ููุตูุฉ ุงูุทุจูุจ ุฅูู ูุฑูู ุงูุชุญูู ุงูู ุนุชู ุฏ ู ู ููุฆุฉ ุงูุตุญุฉ ุจุฏุจู ุนุจุฑ ุงููุงุชุณุงุจ. ุงุญุตู ุนูู ุชุญุฏูุซ ุงูุญุงูุฉ ูู ุฏูุงุฆู.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians