Also known as: SDHAF1 Gene Mutation Test, Mitochondrial Complex II Deficiency Genetic Test
Test Price
2,800 AEDโ Home Collection Available
๐ Results in 3โ4 Weeks
SDHAF1 Gene Mitochondrial Complex II Deficiency Genetic Test in UAE โ 2,800 AED โ DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (available daily 8 AM โ 11 PM).
- Clinical Guidance: Post-Test Telephonic Genetic Counselling included.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The SDHAF1 Gene Mutation Test uses high-depth Next-Generation Sequencing (NGS) to detect pathogenic variants causing Mitochondrial Complex II Deficiency (Leigh syndrome). The assay covers the full coding region, intron-exon boundaries, and flanking regulatory elements, providing >99.9% sensitivity and specificity for germline mutations in this gene. Results are correlated with biochemical and neuroimaging data in accordance with international diagnostic guidelines.
| Feature | DNA Labs UAE โ NGS Panel | Alternative โ Sanger Sequencing |
|---|---|---|
| Precision | >99.9% Sensitivity & Specificity | ~95โ97% for targeted exons |
| Method | Highโdepth NGS (full gene + intronโexon boundaries) | Sanger sequencing of select exons |
| Turnaround Time | 3โ4 Weeks | 4โ6 Weeks |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403
"Genetic results from this NGS panel must be interpreted alongside biochemical markers (lactate, pyruvate) and neuroimaging findings. A negative result does not fully exclude mitochondrial disease; I strongly advise patients to maintain all prescribed therapies and consult their specialist before any change in management."
⚠ Medication Advisory
Do not discontinue prescribed medication without consulting your treating physician. This test is for diagnostic information and does not replace medical advice.
Exclusion Criteria (Patient Safety)
- Active acute infection requiring treatment
- Known allergy to phlebotomy materials (e.g., latex, antiseptic)
- Recent blood transfusion (within 4 weeks)
ER Red Flags
Seek emergency care if you experience severe headache, slurred speech, sudden vision loss, or loss of consciousness after sample collection โ although exceedingly rare, these may indicate vasovagal syncope.
Patient FAQ & Clinical Guidance
1. What is the SDHAF1 gene test used for?
The SDHAF1 NGS test identifies pathogenic variants responsible for mitochondrial complex II deficiency, enabling accurate diagnosis, carrier testing, and prenatal planning for affected families.
2. How is the sample collected and what are the requirements?
A simple blood draw (peripheral whole blood) or a single drop on an FTA card can be used. Preโtest genetic counselling is mandatory to construct a family pedigree. Home phlebotomy is available daily from 8 AM to 11 PM via our VIP Mobile Phlebotomy service.
3. When will I receive my results and who interprets them?
Results are available within 3โ4 weeks and include a comprehensive report. Our DHAโlicensed genetic counsellors provide a free post-test telephonic consultation to explain findings and recommend next steps.
4. Is this test covered by insurance?
We offer direct billing verification with most UAE health insurers. Please send your policy details via WhatsApp +971 54 548 8731 to confirm coverage.
UAE Regulatory & Data Privacy Adherence
Data Protection & Health Information Governance
This service complies with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent is obtained under the provisions of Federal Decree-Law No. 4 of 2016 on Medical Liability. All genetic data is encrypted, stored in UAE-based servers, and never shared with third parties without explicit authorisation.
Clinical & Logistical Metadata
| Test Name | SDHAF1 Gene Mitochondrial Complex II Deficiency NGS Panel |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3โ4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) or FTA Card |
| Methodology Used | High-Throughput Next-Generation Sequencing (NGS) โ Full gene coverage |
| ICD-10-CM Code | G31.89, E88.49 |
| LOINC Code | 92977-1 (Mitochondrial respiratory chain complex II deficiency panel) |
| DHA Facility License & Laboratory Address | License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE โ DNA Labs UAE |
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Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
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Available in Arabic, English, Hindi & Urdu
Preparation Required
["No specific fasting required", "Inform lab of any current medications"]
Medically Reviewed by Dr. Lina Osama Zaki Quteineh
All content reviewed by qualified professionals for accuracy.
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians