Test Price
2,800 AED✅ Home Collection Available
REN Gene Renal Tubular Dysgenesis Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Executive Summary: This high-precision genetic test diagnoses hereditary renal tubular dysgenesis caused by REN gene mutations, using NGS technology and DHA-licensed laboratories with ISO 15189 accreditation and 99.9% diagnostic sensitivity.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 15189 Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a genetic counsellor.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The REN Gene Renal Tubular Dysgenesis Genetic Test employs Next-Generation Sequencing (NGS) to screen the entire coding region of the REN gene for pathogenic variants. It is the definitive molecular diagnosis for autosomal recessive renal tubular dysgenesis (RTD), often presenting in the perinatal period with anuria, oligohydramnios, and severe refractory hypotension.
| Feature | Our Test (NGS) | Closest Alternative |
|---|---|---|
| Diagnostic Precision | 99.9% sensitivity, full gene coverage | Sanger sequencing of selected exons only |
| Methodology | Next-Generation Sequencing (NGS) | Targeted mutation panel |
| Turnaround Time | 3–4 Weeks with ISO cold-chain logistics | 5–6 Weeks without standardized transport |
Physician Insight & Safety Protocols
“A positive REN gene test confirms the diagnosis, but clinical correlation remains paramount. Even with a negative result, other genetic or renal causes must be explored. Please always discuss the implications with a qualified nephrologist or clinical geneticist before making treatment decisions.” – Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory & Medication Guidance
Important Advisory: Do not discontinue prescribed medication without consulting your doctor. This test does not replace ongoing medical management. All results require interpretation by a qualified healthcare professional.
Exclusion Criteria & Emergency Red Flags
Do Not Proceed with Home Collection if:
- Patients currently requiring acute dialysis or intensive care for renal failure are not eligible for home collection; proceed to the nearest emergency department.
- Infants with Potter sequence (severe oligohydramnios) and respiratory distress need immediate NICU admission — test can be ordered in‑hospital.
- This test must be ordered by a physician after genetic counselling; it is not a stand‑alone screening tool.
- If you experience sudden anuria, severe hypotension, or bleeding, seek emergency medical attention immediately.
Patient FAQ & Clinical Guidance
1. How accurate is the REN NGS test for diagnosing renal tubular dysgenesis?
Our NGS assay delivers diagnostic sensitivity exceeding 99.9% for REN gene mutations using a high‑quality DNA sample, validated according to ISO 15189 standards.
2. Is home sample collection available across the UAE for this genetic test?
Yes, a DHA‑licensed phlebotomist performs hospital‑grade blood draw or finger‑prick FTA card collection at your home, with immediate cold‑chain transport to our genetics lab. VIP Mobile Phlebotomy is available daily from 8 AM to 11 PM.
3. Can the REN gene test be used for prenatal diagnosis in a future pregnancy?
After mandatory genetic counselling and pedigree analysis, this can be applied to chorionic villus or amniocentesis samples for early prenatal detection of RTD. Such samples are classified as hospital‑only procedures.
UAE Regulatory & Data Privacy Adherence
Data Protection & Privacy: All procedures comply with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient data is encrypted and access is strictly controlled. Parental/guardian consent is required for individuals under 18 years.
Clinical Safety & Consent: Genetic testing and related clinical procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. All sample collections are performed by DHA-licensed professionals.
Accreditations: ISO 9001:2015 Quality Management System – Certificate No. INT/EGQ/2509DA/3139. Laboratory services are DHA-licensed under facility license number 1143.
Clinical & Logistical Metadata
| Test Name | REN Gene Renal Tubular Dysgenesis Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA) or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | Q63.8, N25.89, Z13.71 |
| LOINC Code | 82949-8 |
| DHA Facility License & Address | DHA License: 1143 | DNA Labs UAE | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians