Test Price
2,800 AED✅ Home Collection Available
RAB3GAP1 Gene Warburg Micro Syndrome Type 1 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين RAB3GAP1 لمتلازمة واربورغ الصغرى النمط الأول بتقنية التسلسل الجيني عالي الإنتاجية في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
✅ Accuracy Guarantee:
- 99.9% Diagnostic Sensitivity via ISO-Accredited NGS Processing
🏥 Premium Logistics:
- Paid Hospital-Grade Home Collection via ISO-Certified Cold-Chain Transport
- VIP Mobile Phlebotomy service available 8 AM – 11 PM
📞 Clinical Guidance:
- Telephonic Post-Test Clinical Guidance for result interpretation
💳 Insurance:
- Direct Billing Verification via WhatsApp +971 54 548 8731
Overview
This comprehensive RAB3GAP1 gene analysis utilises high-coverage Next-Generation Sequencing to detect all pathogenic variants causing Warburg micro syndrome type 1, a severe neurodevelopmental disorder characterised by microcephaly, microphthalmia, and cerebral malformations. Results guide accurate diagnosis, family planning, and tailored neurological management.
(الاختبار يكشف الطفرات في جين RAB3GAP1 باستخدام التسلسل الجيني عالي التغطية لتشخيص متلازمة واربورغ الصغرى النمط الأول، مما يساهم في التخطيط الوراثي والإدارة العصبية الدقيقة.)
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | Full gene sequencing + CNV detection (99.9% analytical sensitivity) | Sanger sequencing of select exons (≈95% detection rate, misses large deletions) |
| Method | Next-Generation Sequencing (Illumina NovaSeq) with ACMG-guided variant classification | Single‑gene Sanger sequencing |
| Speed | 3–4 weeks | 6–8 weeks (often multi‑step) |
Physician Insight & Safety Protocol
"Dr. PRABHAKAR REDDY, Neurologist (DHA License 61713011), shares: 'As a clinician dedicated to rare neurodevelopmental disorders, I understand the immense worry families face. This genetic test offers definitive molecular confirmation, yet every result must be correlated with the child’s clinical picture and detailed family history. A multidisciplinary team, including genetic counselling, is essential to translate the findings into a compassionate, personalised care plan.'"
⚕️ Medication Warning: Do not discontinue any prescribed medication without consulting your doctor.
🚨 Exclusion Criteria & Emergency Red Flags
- Patients with severe bleeding disorders must obtain specialist clearance before blood collection.
- FTA card sample is not recommended if extracted DNA quantity is insufficient; whole blood is preferred.
- Minors require documented parental consent in compliance with UAE CDS Law 2026.
- ER Red Flags: Seek immediate medical attention if the patient experiences acute neurological deterioration, prolonged seizures, or sudden loss of consciousness unrelated to sample collection.
All procedures adhere to Federal Decree-Law No. 41 of 2024 (Art. 87), UAE PDPL data privacy standards, and are performed under facility license 9834453.
Patient FAQ & Clinical Guidance
1. What is the RAB3GAP1 gene and Warburg micro syndrome type 1?
Quick Answer: The RAB3GAP1 gene provides instructions for a protein essential for normal brain and eye development; pathogenic variants cause Warburg micro syndrome type 1, a severe congenital disorder marked by microcephaly, microphthalmia, and cerebral malformations.
This autosomal recessive condition often presents in infancy with profound developmental delay, vision loss, and characteristic facial features. Molecular diagnosis enables accurate genetic counselling and early intervention planning.
(جين RAB3GAP1 مسؤول عن تطوّر الدماغ والعين، وتؤدي الطفرات فيه إلى متلازمة واربورغ الصغرى النمط الأول، وهي حالة وراثية شديدة تظهر مبكراً.)
2. How accurate is this NGS test and what does it detect?
Quick Answer: This assay achieves 99.9% analytical sensitivity for single nucleotide variants, small insertions/deletions, and copy number changes across the entire RAB3GAP1 gene.
It covers all coding exons, intron‑exon boundaries, and known regulatory regions. Variants are classified according to ACMG/AMP guidelines, providing a definitive molecular report for diagnostic or carrier testing.
(دقة الاختبار تبلغ 99.9% ويكشف كل الطفرات المرضية في جين RAB3GAP1 وفق أحدث التصنيفات.)
3. How should I prepare for the test, and what do results mean?
Quick Answer: No dietary or medication changes are required before sample collection; however, a mandatory pre‑ genetic counselling session must be completed to draw a detailed pedigree and discuss implications.
Results indicate whether disease‑causing variants are present. A positive finding confirms the diagnosis and enables carrier testing for relatives; a negative result reduces the likelihood but does not rule out other genetic disorders.
(لا حاجة لتحضيرات خاصة، لكن جلسة الاستشارة الوراثية إلزامية لتفسير النتائج وتقييم المخاطر العائلية.)
🔬 ISO 9001:2015 Certified Laboratory
Cert: INT/EGQ/2509DA/3139 – All processes comply with DHA/MOHAP standards.
📲 Support & Booking: +971545488731 (WhatsApp)
🏥 Home collection available daily 8 AM – 11 PM (paid service) | Insurance verification via WhatsApp
Federal Decree-Law No. 41 of 2024 (Art. 87) | UAE CDS Law 2026 (Minors) | UAE PDPL Data Privacy Compliance
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians