Test Price
2,800 AED✅ Home Collection Available
PROK2 Gene Kallmann Syndrome Type 4 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين PROK2 لمتلازمة كالمان النوع الرابع في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary — خلاصة تنفيذية
- Accuracy Guarantee: 99.9% diagnostic sensitivity for pathogenic variants in the PROK2 gene, performed under ISO 9001:2015 certified processing.
- Premium Logistics: Paid hospital‑grade home collection via ISO certified cold‑chain transport, or VIP mobile phlebotomy within 8 AM–11 PM, 7 days a week.
- Clinical Guidance: Telephonic post‑test counselling with a clinical geneticist to interpret results and plan next steps.
- Insurance: Direct billing verification and pre‑approval support via WhatsApp +971 54 548 8731.
Overview
The PROK2 Gene Kallmann Syndrome Type 4 NGS Test identifies DNA sequence variants in the PROK2 gene responsible for hypogonadotropic hypogonadism and absent sense of smell (anosmia). This next‑generation sequencing assay delivers definitive molecular confirmation of Kallmann syndrome type 4, guiding hormone replacement therapy and reproductive planning. يحدد تحليل جين PROK2 بالتسلسل من الجيل التالي الطفرات المسببة لمتلازمة كالمان النوع الرابع، والتي تتميز بتأخر البلوغ وفقدان حاسة الشم، مما يتيح تأكيد التشخيص والتخطيط العائلي.
| Feature | Our Test (PROK2 Gene NGS) | Closest Alternative (Hormonal Panel) |
|---|---|---|
| Diagnostic Precision | 99.9% sensitivity for exon‑level mutations | ~60‑70% (phenotypic overlap with other hypogonadism) |
| Methodology | Next‑Generation Sequencing (NGS) with copy number analysis | Serum LH, FSH, testosterone/estradiol immunoassay |
| Clinical Turnaround | 3‑4 Weeks with detailed molecular report | Same‑day results, but no genetic aetiology |
Physician Insight & Safety Protocol
“As a physician with extensive experience in reproductive genetics, I recognise that living without a clear diagnosis can be deeply frustrating. The PROK2 gene test often provides the missing biological explanation for delayed puberty and anosmia, enabling precise hormonal treatment and informed family planning decisions. Please remember that every result must be integrated with a full clinical evaluation, and I am available to guide you throughout the process.” — Dr. PRABHAKAR REDDY, DHA License 61713011
Medication Warning
Do not discontinue any prescribed hormonal therapy or other medication without consulting your doctor. Genetic test results may alter treatment strategies, but abrupt cessation can be dangerous.
Safety Exclusion Criteria & Emergency Red Flags
- Active fever, severe infection, or haemodynamic instability precludes routine blood collection.
- Known severe anaemia (Hb <7 g/dL) or bleeding diathesis – contact our medical team for clearance.
- Lack of informed consent or valid genetic counselling documentation (mandatory per UAE CDS Law 2026).
- Seek emergency care if after sample collection you develop: sudden loss of vision, intense headache, chest pain, or fainting. These are rare but require immediate attention.
Patient FAQ & Clinical Guidance
1. What exactly does the PROK2 gene test detect, and how is it related to Kallmann syndrome type 4?
This Next‑Generation Sequencing test identifies mutations in the PROK2 gene, which are directly responsible for Kallmann syndrome type 4 – a congenital disorder causing delayed or absent puberty and anosmia. Because the condition is often misdiagnosed as simple constitutional delay, molecular confirmation is essential. The assay covers the entire coding region plus exon‑intron boundaries, ensuring detection of both point mutations and small deletions. A pre‑test genetic counselling session is mandatory to construct a pedigree and discuss the inheritance pattern.
يكشف اختبار التسلسل الجيني من الجيل التالي عن طفرات في جين PROK2 المسؤول عن متلازمة كالمان النوع الرابع، والتي تسبب تأخر البلوغ وفقدان الشم. تتيح هذه التقنية تأكيد التشخيص الجزيئي ومنع التشخيص الخاطئ.
2. How is the sample collected for this genetic test, and what are the exact requirements?
A trained DHA‑licensed phlebotomist collects a standard whole blood sample, extracted DNA, or a single drop of blood on an FTA card during a scheduled home visit. No fasting or special preparation is needed, and the entire process takes less than 10 minutes. For infants or young children, we offer a specialised paediatric pain‑management protocol. All samples are transported at controlled temperature (2‑8 °C) to our ISO‑accredited facility immediately after collection.
يتم جمع العينة بواسطة فني معتمد من هيئة الصحة إما عن طريق سحب الدم الوريدي، أو الحمض النووي المستخلص، أو بطاقة FTA بقطرة دم واحدة. تصل العينة للمختبر فورًا ضمن سلسلة تبريد محكمة.
3. What is the turnaround time and cost for the PROK2 gene test in the UAE, and does insurance cover it?
Results are typically delivered within 3 to 4 weeks from sample receipt, with a total price of 2800 AED inclusive of genetic counselling and phlebotomy fees. We verify insurance coverage upfront via WhatsApp (+971 54 548 8731) and assist with direct billing to most major UAE insurers. Please note that co‑payments may apply depending on your policy; our team will confirm all financial details before the test.
تصدر النتائج في غضون 3 إلى 4 أسابيع بتكلفة 2800 درهم تشمل الاستشارة الوراثية وسحب العينة. نقوم بالتحقق المسبق من تغطية التأمين والمساعدة في الفوترة المباشرة.
Compliance: This is ordered in accordance with UAE Federal Decree‑Law No. 41 of 2024 (Art. 87) on genetic testing, the 2026 CDS Law governing minors, and the UAE Personal Data Protection Law. Our facility holds ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) and operates under DHA license no. 9834453.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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ISMS 27001:2022
ISO Accredited
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All reports reviewed by DHA-Certified physicians