Test Price
2,600 AED✅ Home Collection Available
NxGen Sequencing for Dravet Syndrome & Early Infantile Epileptic Encephalopathy (EIEE) – Dubai, UAE
Executive Summary & Core Metrics
This advanced genetic screening service delivers precision diagnostics with a 99.9% accuracy rate for Dravet syndrome and Early Infantile Epileptic Encephalopathy (EIEE), utilizing ISO-accredited next-generation sequencing technology.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Hospital-Grade Home Collection via ISO Certified Cold-Chain and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance with a Consultant Medical Geneticist.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
This targeted NxGen sequencing panel interrogates a curated set of genes (SCN1A, PCDH19, STXBP1, CDKL5, KCNQ2, ARX, and others) associated with Dravet syndrome and EIEE. All sequencing is performed on an Illumina platform with >100x average depth of coverage. Pathogenic, likely pathogenic, and variants of uncertain significance (VUS) are confirmed via bi-directional Sanger sequencing. The test is processed under ISO 9001:2015 certified facilities, ensuring a 40‑working‑day reporting timeline with rigorous clinical validation.
| Parameter | Our NxGen Dravet/EIEE Test | SCN1A Single-Gene Test | Whole Exome Sequencing (WES) |
|---|---|---|---|
| Method | NGS + Sanger Confirmation | Sanger Sequencing | NGS only (with variable interpretability) |
| Genes Analyzed | SCN1A, PCDH19, STXBP1, CDKL5, KCNQ2, ARX, and more (expansive panel) | SCN1A only | All ~20,000 genes (may include incidental findings) |
| Detection of Copy Number Variants | Yes, via NGS depth‑based analysis | Limited | Possible, but often requires additional analysis |
| Turnaround Time | 40 working days | 4–6 weeks | 8–12 weeks |
| Price (AED) | 2,600 AED | ≈1,500 AED | ≈4,000 AED |
Powered by ISO 9001:2015 certified laboratory. DHA Facility License: 1143.
Physician Insight & Safety Protocols
“As a Consultant Medical Geneticist practicing in the UAE, I recognize the diagnostic odyssey families endure when facing early-onset epilepsy. This comprehensive NxGen panel provides a critical molecular roadmap, enabling precise therapeutic intervention and informed family counseling. However, results must always be contextualized within the full clinical picture by a qualified specialist.”
Clinical Advisory & Medication Safety
⚠️ Do not discontinue or alter prescribed anticonvulsant therapy without direct consultation with your treating neurologist or epileptologist. Abrupt cessation of medication can precipitate life-threatening withdrawal seizures or status epilepticus.
Exclusion Criteria & Emergency Red Flags
- Inability to obtain 10 mL venous blood (e.g., severe venous access issues).
- Failure to complete and sign the mandatory Whole Exome Sequencing Consent Form (Form 37).
- Active severe infection with coagulopathy or hemodynamic instability.
🚨 Seek Emergency Care If:
- Prolonged seizure lasting more than 5 minutes or repeated seizures without recovery.
- Respiratory distress, cyanosis, or loss of consciousness.
Patient FAQ & Clinical Guidance
1. What does this NxGen test detect?
This test detects pathogenic variants in genes responsible for Dravet syndrome and early infantile epileptic encephalopathies using high-coverage NGS. It covers SCN1A, PCDH19, STXBP1, CDKL5, KCNQ2, ARX, and numerous other genes, identifying point mutations, splice variants, and copy number changes with Sanger‑validated accuracy.
2. How is the sample collected?
A trained phlebotomist collects 10 mL of venous blood in two lavender-top EDTA tubes, refrigerated immediately. Home collection is available 8 AM – 11 PM daily via our VIP Mobile Phlebotomy service; the sample must be shipped cold (never frozen) and reach our lab by 9 AM for same‑day accessioning.
3. When will I receive my results?
Results are reported within 40 working days, accompanied by a detailed clinical report. You will also receive a complimentary telephonic guidance session with a Consultant Medical Geneticist to explain the findings and next steps.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance Framework
DNA Labs UAE strictly adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access-controlled, and processed exclusively within the UAE jurisdiction. Clinical safety and patient consent protocols are governed by Federal Decree-Law No. 4 of 2016 on Medical Liability.
Clinical & Logistical Metadata
| Test Name | NxGen Sequencing for Dravet Syndrome & Early Infantile Epileptic Encephalopathy (EIEE) |
| Price (AED) | 2,600 AED |
| Turnaround Time | 40 Working Days |
| Sample Type / Matrix | Peripheral Whole Blood (10 mL in Lavender-Top EDTA Tubes). VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection Available (8 AM – 11 PM Daily). |
| Methodology Used | Next-Generation Sequencing (NGS) with Confirmatory Sanger Sequencing & CNV Detection |
| ICD-10-CM Code | G40.83, G40.4 |
| LOINC Code | 95406-2 |
| DHA License & Address | DHA Facility License Number: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians