Test Price
2,800 AED✅ Home Collection Available
LBR Gene Pelger-Huët Anomaly Next-Generation Sequencing (Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين LBR لشذوذ بيلغر-هويت بتقنية NGS في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary / ملخص تنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited NGS Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by DHA-licensed specialists.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ضمان الدقة: 99.9% حساسية تشخيصية عبر معالجة معتمدة ISO 9001:2015. خدمة جمع العينات المنزلية عبر سلسلة تبريد معتمدة. إرشاد سريري هاتفي بعد النتيجة. التحقق من التأمين عبر واتساب.
Test Overview / نظرة عامة على التحليل
The LBR Gene Pelger-Huët Anomaly Genetic Test is a comprehensive next-generation sequencing assay that analyzes the entire coding region of the LBR gene to detect heterozygous or homozygous variants associated with Pelger-Huët anomaly and related dysmorphology syndromes. (تحليل الحمض النووي لجين LBR بتقنية NGS يفحص كامل المنطقة المشفرة للكشف عن الطفرات المرتبطة بشذوذ بيلغر-هويت.)
| Feature | Our Test (ISO-Accredited) | Closest Alternative |
|---|---|---|
| Precision | 99.9% Analytical Sensitivity via Illumina NovaSeq & clinical-grade bioinformatics | Sanger sequencing of limited regions; may miss deep intronic mutations |
| Methodology | NGS (Next-Generation Sequencing) – full gene coverage with CNV detection | Capillary sequencing; lower throughput |
| Turnaround Time | 3 to 4 Weeks (DHA-compliant) | 5–8 weeks typical |
Clinical Indications & Specialist Intent
Pediatricians
Evaluating children with unexplained dysmorphism, recurrent infections, or suspected hereditary neutropenia; Pelger-Huët anomaly screening guides early intervention and genetic counseling.
Neonatologists
Confirming suspected Pelger-Huët anomaly in newborns with abnormal neutrophil morphology on peripheral smear, helping differentiate from transient neonatal conditions.
Clinical Geneticists
Establishing molecular diagnosis for family planning, cascade testing, and precise genotype-phenotype correlation in dysmorphology syndromes linked to LBR mutations.
Physician Insight & Safety Protocol
Dr. Prabhakar Reddy (DHA License: 61713011), our Lead Clinical Geneticist, emphasizes: “This test detects LBR gene variants that cause benign hereditary Pelger-Huët anomaly; however, a positive result should be clinically correlated with complete blood count morphology and family history. Genetic counseling is crucial to understand inheritance patterns and potential implications for offspring, but in most cases, Pelger-Huët anomaly does not compromise immune function. Patients should not alter any prescribed therapy without consulting their managing physician.”
⚠️ Medication Advisory: Do not discontinue any prescribed medication or supplement based solely on genetic test results. Always consult your treating doctor before making changes to your medical regimen.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals with active febrile illness or uncontrolled infection should postpone sample collection to avoid confounding blood parameters.
- Exclusion: Patients on high-dose steroid therapy may exhibit altered leukocyte morphology; clinical history must be provided for accurate interpretation.
- ER Red Flags: If your child develops sudden pallor, petechiae, or signs of sepsis, seek immediate emergency care – do not wait for genetic test results.
UAE Regulatory Compliance & Data Privacy
Our laboratory operates under Federal Decree-Law No. 41 of 2024 on Health Data (Article 87), ensuring ethical handling of genetic information. For minors, parental consent is mandatory per CDS Law 2026. All patient data is protected in accordance with UAE Personal Data Protection Law (PDPL). Facility license: 9834453. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139).
Patient FAQ & Clinical Guidance
How does the LBR gene test diagnose Pelger-Huët anomaly, and what does a positive result mean?
This NGS-based identifies pathogenic variants in the LBR gene that cause the characteristic hyposegmentation of neutrophil nuclei seen in Pelger-Huët anomaly; a positive result confirms hereditary Pelger-Huët anomaly but typically indicates a benign condition with normal immune function, requiring no treatment beyond genetic counseling. (يكشف اختبار NGS عن طفرات جين LBR التي تسبب نقص تجزئة نوى العدلات، والإيجابية تؤكد شذوذ بيلغر-هويت الوراثي الحميد ولا تستدعي علاجاً.)
What sample types are accepted, and is home collection available in Dubai and Abu Dhabi?
We accept whole blood, extracted DNA, or one drop of blood on an FTA Card; our ISO-certified VIP mobile phlebotomy team provides hospital-grade home collection across all UAE emirates, including Dubai, Abu Dhabi, and Sharjah, with cold-chain logistics ensuring sample stability. (نقبل الدم الكامل أو الحمض النووي المستخلص أو قطرة دم واحدة على بطاقة FTA؛ تتوفر خدمة جمع العينات المنزلية المتنقلة عبر الإمارات.)
What is the turnaround time, and how will I receive my confidential results?
Results are typically ready within 3 to 4 weeks and are delivered via a secure, encrypted online portal with optional telephonic clinical guidance by a DHA-licensed genetic counselor; direct billing to major insurers can be verified before collection. (النتائج جاهزة خلال 3-4 أسابيع وتُقدم عبر بوابة إلكترونية آمنة مع استشارة هاتفية اختيارية؛ نتحقق من التغطية التأمينية مسبقًا.)
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
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Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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