Test Price
2,800 AED✅ Home Collection Available
LAMA3 Gene (Epidermolysis Bullosa, Junctional, Herlitz Type) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين LAMA3 للكشف عن انحلال البشرة الفقاعي الموصلي من نوع هيرليتز باستخدام تقنية التسلسل الجيني من الجيل التالي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary:
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in Result Interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي: يوفر هذا الاختبار الجيني فائق الدقة تشخيصًا موثوقًا لمرض انحلال البشرة الفقاعي الموصلي من نوع هيرليتز الناجم عن طفرات جين LAMA3، وفق أعلى المعايير الدولية المعتمدة من هيئة الصحة بدبي، مع خدمة سحب دم منزلي متميزة واستشارة ما بعد الفحص.
Comprehensive Test Overview
This advanced Genetic Test sequences the entire LAMA3 gene to detect pathogenic variants causing Herlitz junctional epidermolysis bullosa (JEB-H), a severe blistering skin disorder presenting at birth. Using Next-Generation Sequencing (NGS) technology, it delivers unparalleled diagnostic precision, enabling early intervention and genetic counseling for affected families in the UAE.
يفحص هذا الفحص الجيني المتطور الجين LAMA3 بالكامل لتحديد الطفرات المسببة لمرض انحلال البشرة الفقاعي الموصلي الشديد، مما يتيح التشخيص المبكر والإرشاد الوراثي للعائلات.
Test Specifications
- Methodology: NGS (Next Generation Sequencing)
- Sample Requirements: Blood (whole blood, extracted DNA, or one drop on FTA Card)
- TAT (Turnaround Time): 3 to 4 Weeks
- Price: 2800 AED (all-inclusive, excluding optional home collection fee)
- Pre-Test Information: Clinical history and a genetic counseling session to draw a pedigree chart of affected family members are mandatory.
| Feature | Our LAMA3 NGS Test | Alternative (Gene Panel / Sanger) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity; full gene coverage including deep intronic regions | 80-90% sensitivity; may miss large deletions/duplications or novel variants |
| Method | Next Generation Sequencing (Illumina platform) | Sanger sequencing or targeted gene panels (limited coverage) |
| Turnaround | 3–4 weeks (cold‑chain stabilized sample) | 5–8 weeks (often without cold‑chain logistics) |
| Regulatory Compliance | ISO 9001:2015, DHA/MOHAP, Federal Decree-Law No. 41 of 2024 | Variable; may lack UAE-specific accreditation |
Physician Insight & Safety Protocol
“As a DHA-licensed dermatologist, I emphasize that this genetic test is a cornerstone for confirming Herlitz JEB, yet it must always be interpreted alongside clinical findings. A negative result does not rule out related blistering disorders, and all families should receive thorough genetic counseling. We remain committed to guiding you through every step with empathy and precision.”
— Dr. Prabhakar Reddy, DHA License: 61713011
⚠️ Medication Safety Notice
Do not discontinue any prescribed medication or topical treatment without consulting your doctor. Abrupt cessation of wound care or systemic therapies can precipitate severe blistering and life-threatening infections in epidermolysis bullosa.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Patients with active systemic infection, recent blood transfusion (within 2 weeks), or those unable to provide informed consent (for minors, legal guardian consent is mandatory per UAE CDS Law 2026).
- ER Red Flags: Rapidly spreading bullae with fever, signs of sepsis, respiratory distress (laryngeal involvement), or failure to thrive in a neonate—seek immediate emergency care irrespective of test timing.
- Data Privacy: Your genetic data is protected under UAE PDPL and processed strictly within DHA‑licensed facilities (Facility License: 9834453).
Frequently Asked Questions
What does the LAMA3 Genetic Test detect?
Snippet: This test identifies disease‑causing mutations in the LAMA3 gene responsible for Herlitz junctional epidermolysis bullosa with near‑100% accuracy.
It screens the entire coding region and splice sites for point mutations, small insertions/deletions, and copy number variants, enabling definitive molecular diagnosis and differentiation from other epidermolysis bullosa subtypes.
ماذا يكشف اختبار جين LAMA3 الجيني؟
يكشف هذا الاختبار الطفرات المسببة لمرض انحلال البشرة الفقاعي الموصلي من نوع هيرليتز بدقة شبه كاملة، عبر مسح كامل المنطقة المشفرة ومواقع التوصيل الجيني.
Why is genetic counselling required before the test?
Snippet: Mandatory pre‑test genetic counselling maps your family’s inheritance pattern and ensures informed consent, meeting UAE Federal Decree‑Law No. 41 of 2024 requirements.
Our certified genetic counsellors construct a detailed pedigree chart, explain possible outcomes, and discuss reproductive options, guaranteeing you understand the test’s benefits, limitations, and potential psychosocial impact.
لماذا يتطلب الفحص استشارة وراثية مسبقة؟
الاستشارة الوراثية الإلزامية ترسم شجرة العائلة وتضمن الموافقة المستنيرة، وفق المرسوم الاتحادي رقم 41 لسنة 2024، مما يساعد على فهم النتائج والخيارات الإنجابية.
How are samples collected and transported in the UAE?
Snippet: A DHA‑certified phlebotomist collects blood at your home using an ISO‑certified cold‑chain kit, preserving DNA integrity from 8 AM to 11 PM.
The sample is immediately placed in a temperature‑controlled transport container, and all logistics comply with UAE PDPL and ISO 9001:2015 standards. Whole blood, extracted DNA, or a single drop on an FTA card are accepted, offering maximum flexibility.
كيف يتم سحب العينات ونقلها في الإمارات؟
يقوم فني معتمد من هيئة الصحة بدبي بسحب الدم منزليًا باستخدام حافظة تبريد معتمدة تحافظ على الحمض النووي من 8 صباحًا حتى 11 مساءً، مع الالتزام بمعايير الخصوصية والجودة.
This complies with Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 for minors, and UAE Personal Data Protection Law. ISO 9001:2015 Certification: INT/EGQ/2509DA/3139. Facility License: 9834453.
For emergencies, please call 998 or visit the nearest hospital. This page is for informational purposes and does not replace professional medical advice.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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