Test Price
2,800 AED✅ Home Collection Available
GNPTAB Gene Mucolipidosis Type II Alpha/Beta Genetic Test in UAE
✅ Accuracy Guaranteed: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
🚑 Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
🩺 Clinical Guidance: Complimentary Telephonic Post-Test Result Interpretation by DHA-Licensed Consultant Medical Geneticist.
💳 Insurance & Billing: Direct Insurance Verification via WhatsApp +971 54 548 8731.
Executive Summary & Core Metrics
This advanced next-generation sequencing test analyzes the entire GNPTAB gene to detect pathogenic variants causing Mucolipidosis II (I-cell disease), providing 99.9% diagnostic sensitivity for all mutation types including copy number variations. The all-inclusive price of 2800 AED covers home collection, cold-chain logistics, and post-test telephonic clinical guidance by a licensed medical geneticist.
Test Overview & Methodology
The test employs next-generation sequencing (NGS) with copy number variation (CNV) detection to comprehensively interrogate all coding exons and flanking intronic regions of the GNPTAB gene. Unlike traditional Sanger sequencing, which targets selected exons only, this approach captures deep intronic variants and large rearrangements that standard methods miss.
| Feature | GNPTAB NGS Test | Sanger Sequencing |
|---|---|---|
| Methodology | NGS (Next Generation Sequencing) + CNV detection | Sanger sequencing of selected exons only |
| Diagnostic Sensitivity | 99.9% (all mutation types & large rearrangements) | ~85% (misses deep intronic/CNV mutations) |
| Turnaround Time | 3-4 Weeks | 4-6 Weeks |
| Price | 2800 AED (All-Inclusive) | 3500 AED (Often additional costs) |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Geneticist, I emphasize that a GNPTAB mutation report provides powerful molecular confirmation, but it must always be interpreted alongside clinical symptoms and enzymatic assays. This test is a vital step for early diagnosis in at-risk families, yet its full clinical correlation belongs in the hands of a qualified genetic specialist. Patients should never alter prescribed medications without consulting their treating physician.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory: Medication Safety
Do not discontinue or modify prescribed medication without consulting your doctor.
Genetic test results serve as diagnostic guidance and do not supersede ongoing medical management. Always discuss any planned changes to treatment with your primary healthcare provider.
Exclusion Criteria & Emergency Indicators
- Active severe infection or febrile illness on the day of collection.
- Recent blood transfusion (< 7 days) or known severe coagulopathy.
- Inability to provide informed consent. For minors, parental/guardian consent is mandatory under UAE law.
- If you experience sudden lethargy, persistent vomiting, seizures, or breathing difficulty, seek emergency care immediately — this test is elective and not intended for acute metabolic crisis.
Patient FAQ & Clinical Guidance
1. What is the GNPTAB Gene Mucolipidosis Type II Alpha/Beta Genetic Test?
This advanced next-generation sequencing test analyzes the entire GNPTAB gene to detect pathogenic variants causing Mucolipidosis II (I-cell disease), offering 99.9% diagnostic sensitivity for any known mutation and copy number changes within 3–4 weeks. It is the gold standard for molecular confirmation of this rare lysosomal storage disorder.
2. Why is a pre-test genetic counselling session mandatory?
Genetic counselling is required to construct a detailed family pedigree, assess inheritance risks, discuss reproductive options, and provide informed consent. This process aligns with UAE Federal Decree-Law No. 45 of 2021 on Personal Data Protection and Federal Law No. 2 of 2019 concerning health data usage.
3. How long does the GNPTAB DNA test take and what is the total cost in the UAE?
Turnaround time is 3 to 4 weeks from sample receipt, and the all-inclusive price is 2800 AED. This covers home collection via VIP mobile phlebotomy, temperature-controlled cold-chain logistics, and a post-test telephonic clinical guidance session with a DHA-licensed consultant.
4. What sample type is required for this genetic test?
A standard peripheral whole blood sample collected in an EDTA tube is required. For patients unable to provide blood, an alternative buccal swab or saliva sample may be accepted after prior consultation with our genetics team.
5. Who will interpret my results and provide follow-up care?
Your results will be reviewed and interpreted by a Consultant Medical Geneticist who will issue a detailed clinical report. A complimentary telephonic session is scheduled to explain findings, discuss implications for family members, and coordinate any necessary referrals.
UAE Regulatory & Data Privacy Adherence
This test is performed in full compliance with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) — ensuring all genetic data is stored, processed, and transmitted with strict confidentiality safeguards.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields — governing the secure handling of electronic health records and telemedicine consultations.
- Federal Decree-Law No. 4 of 2016 on Medical Liability — establishing patient consent protocols and clinical safety standards for diagnostic procedures.
DNA Labs UAE is a DHA-licensed facility (License No. 1143) operating under ISO 9001:2015 certified processes, with all genetic results stored in encrypted, access-controlled systems.
Clinical & Logistical Metadata
| Test Name | GNPTAB Gene Mucolipidosis Type II Alpha/Beta Genetic Test |
| Price (AED) | 2800 AED (All-Inclusive) |
| Turnaround Time | 3-4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood (EDTA) |
| Methodology Used | Next-Generation Sequencing (NGS) + CNV Detection |
| ICD-10-CM Code | E77.0 (Mucolipidosis II) |
| LOINC Code | 82310-1 (Gene targeted sequencing) |
| DHA Facility License & Address | DHA License No. 1143 — Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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