Test Price
2,800 AED✅ Home Collection Available
GFI1 Gene Severe Congenital Neutropenia Type 2 (Autosomal Dominant) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين GFI1 لمرض قلة العدلات الخلقي الشديد من النوع 2 (صبغي جسدي سائد) بتقنية NGS في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited NGS Processing.
- Premium Logistics: Hospital-Grade Home Collection with ISO Certified Cold-Chain and VIP Mobile Phlebotomy (8 AM – 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance for result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
يقدم هذا التحليل المتقدم تسلسلاً جينيًا كاملاً لجين GFI1 لتشخيص قلة العدلات الخلقي الشديد من النوع 2 (صبغي جسدي سائد) بدقة تشخيصية تصل إلى 99.9% عبر مختبر معتمد ISO. يتضمن خدمة سحب عينات منزلية عالية الجودة مع إمكانية استشارة وراثية، وتوجيه طبي بعد النتيجة، وتحقق مباشر من التأمين عبر واتساب.
Clinical Overview
This advanced Next‑Generation Sequencing (NGS) test comprehensively analyses the GFI1 gene to diagnose severe congenital neutropenia type 2, an autosomal dominant disorder that predisposes patients to life‑threatening infections and haematological malignancies. يُشخّص هذا الفحص الجيني الطفرة المسببة لقلة العدلات الخلقي الشديد من النوع 2 المرتبط بجين GFI1.
| Feature | Our Test (NGS) | Closest Alternative (Single‑Gene Sanger Sequencing) |
|---|---|---|
| Precision | 99.9% diagnostic sensitivity; full gene coverage including deep intronic regions | ~95% sensitivity; may miss large deletions/duplications |
| Method | Next‑Generation Sequencing (Illumina® platform, 100x depth) | Capillary electrophoresis Sanger sequencing |
| Speed | 3–4 weeks | 6–8 weeks |
| Clinical Value | Concurrent analysis of all coding and regulatory regions | Limited to known mutations; sequential analysis if first test negative |
Physician Insight & Safety Protocol
“As a specialist, I understand the anxiety that comes with a family history of severe neutropenia. This test offers definitive clarity, but remember that a positive result must be correlated with clinical findings and family history to tailor a precise care plan. We are here to guide you every step of the way.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
⚠️ Medication Safety Notice:
Do not discontinue any prescribed medication (including G‑CSF, antibiotics, or immunomodulators) without consulting your managing physician. Abrupt changes can lead to severe infections or complications.
Patient Safety & Exclusion Criteria
- Mandatory Pre‑requisite: A clinical history review and pre‑test genetic counselling session with a certified genetic counsellor are compulsory. The counselling must include drawing a pedigree chart of affected family members.
- Sample Requirements: Whole blood in EDTA, extracted DNA (≥2 µg), or a dried blood spot on FTA card. Haemolysed, clotted, or improperly stored samples will be rejected.
- Minors: Testing for asymptomatic minors must strictly adhere to UAE CDS Law 2026 provisions and require consent from both legal guardians.
- Emergency Red Flags: If the patient (especially a child) experiences fever ≥38.3°C, new mouth ulcers, severe fatigue, or signs of systemic infection, do not wait for test results—seek immediate emergency care. Neutropenic fever is a medical emergency.
Frequently Asked Questions (Clinical Guidance)
1. What is the GFI1 gene test and who should consider it?
GFI1 Genetic identifies mutations causing severe congenital neutropenia type 2 for precise management. It is recommended for infants or children with recurrent severe infections, unexplained neutropenia, or a family history of congenital neutropenia. Adults with chronic neutropenia awaiting bone marrow evaluation may also benefit.
يُحدد فحص GFI1 بالتسلسل الجيني الطفرات المسببة لقلة العدلات الخلقي الشديد من النوع 2 لتوجيه العلاج الدقيق. يُوصى به للأطفال الذين يعانون من التهابات متكررة شديدة أو نقص عدلات غير مفسر.
2. How is the sample collected and what is the turnaround time?
Home-based phlebotomy collects blood or DNA samples, and NGS results are ready in 3 to 4 weeks. Our VIP mobile team visits your home, workplace, or hospital (8 AM–11 PM), following cold‑chain protocols to guarantee sample stability. An adult must be present for consent.
يتم سحب العينة منزليًا بواسطة فريق تمريض متنقل، وتصدر النتائج خلال 3 إلى 4 أسابيع. نضمن نقل العينة بسلسلة تبريد معتمدة.
3. What do positive or negative results mean for my child’s health?
Positive GFI1 result confirms severe congenital neutropenia type 2, guiding lifelong monitoring and tailored treatment. A positive finding alerts your paediatric haematologist to initiate G‑CSF therapy, infection prophylaxis, and surveillance for myelodysplasia. A negative result reduces (but does not eliminate) the likelihood of this specific genetic cause; other neutropenia genes may need investigation.
النتيجة الإيجابية تؤكد الإصابة بقلة العدلات الخلقي الشديد وتوجه نحو العلاج بعامل التحفيز ومتابعة نخاع العظم. النتيجة السلبية لا تنفي وجود طفرات جينية أخرى.
UAE Regulatory Compliance & Accreditation
- Testing performed in accordance with Federal Decree‑Law No. 41 of 2024 (Art. 87) and UAE PDPL data privacy standards.
- Minors’ testing follows 2026 CDS Law provisions; mandatory dual guardian consent and genetic counselling.
- ISO 9001:2015 Certified Quality Management System (Cert: INT/EGQ/2509DA/3139).
- Licensed facility: DHA/MOHAP No. 9834453.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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