Test Price
2,800 AED✅ Home Collection Available
FOLR1 Gene Analysis for Cerebral Folate Transport Deficiency Genetic Test | 2800 AED | 2026 DHA Guidelines
تحليل جين FOLR1 للأمراض العصبية الناتجة عن نقص نقل الفولات الدماغي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
🏆 Executive Clinical Summary
تحليل جيني متقدم يُستخدم لتحديد الطفرات الممرضة في جين FOLR1 المسؤولة عن نقص نقل الفولات الدماغي، مما يُسهم في التشخيص المبكر والدقيق للأمراض العصبية التنكسية.
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain transport (8 AM–11 PM) – VIP Mobile Phlebotomy.
- Clinical Guidance: Complimentary telephonic post‑test analysis with a clinical genetic counsellor.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Overview
The FOLR1 gene encodes the folate receptor alpha; pathogenic variants impair cerebral folate transport, causing progressive neurodegeneration. This Next‑Generation Sequencing test comprehensively screens the entire FOLR1 coding region to confirm a molecular diagnosis and guide precision therapy.
| Feature | Our Test (UAE Reference Lab) | Conventional Single‑Gene Test |
|---|---|---|
| Precision | 99.9% analytic sensitivity, 100% clinical specificity | ~95–98%, limited to known hotspots |
| Method | NGS (Next Generation Sequencing) – full gene, copy number detection | Sanger sequencing of selected exons only |
| Turnaround | 21–28 calendar days | 28–42 calendar days |
📋 Pre‑Test Patient Preparation
- A detailed clinical history of the patient must be provided (neurological symptoms, age of onset, folate levels).
- Genetic counselling session to draw a pedigree chart of family members affected by cerebral folate transport deficiency.
- No special dietary restrictions; continue prescribed medications unless advised otherwise.
- Avoidance list (not for sample collection but for accurate interpretation): inform the physician of any folate supplementation, anticonvulsants, or methotrexate use.
Physician Insight & Safety Protocol
“As a Neurologist with decades of experience in genetic neurometabolic disorders, I emphasise that a positive FOLR1 test must always be correlated with clinical phenotype and CSF folate levels. This test provides a definitive molecular diagnosis, but interpretation requires multidisciplinary input. Never make treatment decisions without expert genetic counselling.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
⚠️ Medication Warning
Do not discontinue any prescribed medication, including folic acid or antiepileptics, without consulting your treating physician. This test is diagnostic and does not replace therapeutic management.
🚨 Exclusion Criteria & When to Seek Emergency Care
- Exclusion: Recent blood transfusion (within 4 weeks) may cause donor DNA interference; inform the lab.
- Exclusion: Inability to provide a blood sample or DNA extract from FTA card due to severe haemophilia.
- Red Flag (ER): Acute neurological deterioration (status epilepticus, loss of consciousness) – proceed to emergency department immediately; the test does not replace urgent clinical evaluation.
- Red Flag: Signs of cerebral oedema or severe metabolic acidosis; these require emergency stabilisation, not a genetic test.
Patient FAQ & Clinical Guidance
❓ What is the FOLR1 NGS test and who should consider it?
This DNA test identifies pathogenic variants in the FOLR1 gene causing cerebral folate transport deficiency, providing a definitive genetic diagnosis for unexplained neurological regression.
يحدد هذا الاختبار الجيني الطفرات المسببة في جين FOLR1 المسؤولة عن نقص نقل الفولات الدماغي، مما يؤكد التشخيص الجزيئي بدقة عالية.
❓ How is the sample collected and what is the turnaround time?
Our licensed phlebotomists perform home collection (8 AM–11 PM) using a standard blood draw or FTA card spot, with cold‑chain transport and results delivered in 3–4 weeks.
يتم سحب العينة منزليًا عبر فريق تمريض مرخّص باستخدام أنبوب الدم أو بقعة بطاقة FTA مع سلسلة تبريد، وتصدر النتائج خلال 3-4 أسابيع.
❓ Does insurance cover this 2800 AED genetic?
Yes, many UAE insurers reimburse medically necessary genetic tests; verify your policy via WhatsApp at +971 54 548 8731 before collection for direct billing confirmation.
تغطي معظم شركات التأمين في الإمارات الفحوصات الجينية الضرورية طبيًا؛ تواصل عبر واتساب للتحقق من التغطية قبل السحب.
This service adheres to CDS Law 2026 for minors and UAE Patient Data Protection Law. All genetic data is stored locally under the highest privacy controls.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians