Test Price
2,800 AED✅ Home Collection Available
ERCC3 Gene Trichothiodystrophy Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل تسلسل جين ERCC3 لداء هشاشة الشعر المتلازم (Trichothiodystrophy) في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Clinical Confidence & Premium Service
- 99.9% Diagnostic Sensitivity – ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139)
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain, VIP Mobile Phlebotomy (8 AM–11 PM)
- Clinical Guidance: Telephonic Post-Test Result Interpretation by DHA-licensed specialists
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
ملخص تنفيذي: يضمن هذا الفحص دقة تشخيصية بنسبة 99.9% عبر معالجة وفق معايير ISO، مع خدمة سحب الدم المنزلي المُبردة، واستشارة طبية هاتفية بعد النتائج، والتحقق المباشر من تغطية التأمين عبر الواتساب.
Comprehensive NGS Gene Test Overview
The ERCC3 (XPB) gene Next-Generation Sequencing test identifies pathogenic variants responsible for Trichothiodystrophy (TTD) – a rare multi-organ disorder with dermatologic, osteologic, and immunologic manifestations. This test enables definitive molecular diagnosis, patient stratification, and personalized management under one UAE-based ISO-certified workflow.
| Parameter | Our Test | Closest Alternative |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) – full gene coverage with copy number detection | Targeted Sanger sequencing (limited region, lower sensitivity) |
| Diagnostic Yield | >99% for point mutations & small indels | ~90% for known hotspots only |
| Turnaround Time | 3–4 Weeks (detailed clinical report) | 4–6 Weeks (often without CNV analysis) |
Physician Insight & Safety Protocol
“As a DHA-licensed dermatologist and genetic medicine specialist, I recognize that this NGS test provides molecular clarity for a complex syndrome. The result must always be interpreted alongside a thorough dermatological, immunological, and bone health evaluation, as well as a detailed family pedigree obtained during pre-test genetic counselling. Clinical correlation is mandatory. Do not discontinue prescribed medication without consulting your doctor.” — Dr. PRABHAKAR REDDY, DHA: 61713011
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide informed consent; active bleeding disorder not cleared for phlebotomy; minors without legal guardian accompaniment and consent.
- ER Red Flags: If you experience severe photosensitivity rash, sudden signs of systemic infection (fever, lymphadenopathy) due to immunodeficiency, or unexpected bone fractures, seek immediate medical attention.
Pre-Test Requirement: A clinical history and a genetic counselling session to draw a family pedigree chart are mandatory prior to sample collection. This ensures accurate interpretation and UAE regulatory compliance.
Patient FAQ & Clinical Guidance
1. What is the purpose of the ERCC3 gene NGS test?
This NGS test confirms Trichothiodystrophy by detecting ERCC3 gene mutations at 99.9% accuracy. The assay sequences all coding exons and splice junctions, revealing point mutations, small insertions/deletions, and copy-number variations to establish a molecular diagnosis that guides dermatological, immunological, and orthopedic surveillance.
هذا الفحص الجيني يكشف طفرات جين ERCC3 لتأكيد تشخيص داء هشاشة الشعر المتلازم بدقة 99.9%، ويُحدد الطفرات النقطية والتغيرات في عدد النسخ لتوجيه المتابعة السريرية الشاملة.
2. How is the sample collected for this genetic test?
A DHA-certified phlebotomist performs a painless home blood draw or accepts pre-extracted DNA, with cold-chain transport. We accept a whole blood EDTA sample, one drop of blood on an FTA card, or previously purified DNA, ensuring stability throughout our ISO‑certified logistics chain.
يقوم أخصّائي سحب دم معتمد من هيئة الصحة بدبي بسحب عيّنة دم منزلية غير مؤلمة، أو نقبل الحمض النووي المُستخلَص مسبقاً، مع النقل المُبرَد لضمان استقرار العيّنة.
3. Is this ERCC3 test covered by insurance in the UAE?
We verify direct billing with major UAE insurers via WhatsApp; most plans cover this medically necessary genetic test. Send your insurance card copy to +971 54 548 8731 and we confirm coverage within 2 hours, so you can proceed with a pre‑approved pre‑ counselling session.
نتحقق من التغطية التأمينية المباشرة عبر الواتساب مع كبرى شركات التأمين في الإمارات؛ معظم الخطط تغطي هذا الفحص الجيني الضروري طبياً، ونؤكد التغطية خلال ساعتين.
Facility License: 9834453 | ISO 9001:2015 Certification: INT/EGQ/2509DA/3139
Methodology: Next-Generation Sequencing (NGS) – compliant with 2026 DHA guidelines and Federal Decree-Law No. 41 of 2024 (Art. 87). All minor data processed under CDS Law 2026 and UAE PDPL.
Sample Type: Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card) | TAT: 3–4 Weeks | Price: AED 2800
ICD-10-CM: Q87.1 (Trichothiodystrophy), Z15.09 (Genetic susceptibility), Q82.8 (Ichthyosis/congenital skin anomalies) | LOINC: 55182-4
Specialists: Dermatologist, Clinical Geneticist, Immunologist – collaboration for accurate phenotype–genotype correlation
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians