Test Price
2,800 AED✅ Home Collection Available
ERCC3 Gene Trichothiodystrophy Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Clinical Confidence & Premium Service
- 99.9% Diagnostic Sensitivity – ISO 9001:2015 accredited processing (Cert: INT/EGQ/2509DA/3139)
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Daily 8 AM–11 PM)
- Clinical Guidance: Telephonic Post-Test Result Interpretation by DHA-licensed specialists
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731
Test Overview & Methodology
The ERCC3 (XPB) gene Next-Generation Sequencing test identifies pathogenic variants responsible for Trichothiodystrophy (TTD) – a rare multi-organ disorder with dermatologic, osteologic, and immunologic manifestations. This test enables definitive molecular diagnosis, patient stratification, and personalized management under one UAE-based ISO-certified workflow.
| Parameter | Our Test | Closest Alternative |
|---|---|---|
| Methodology | Next-Generation Sequencing (NGS) – full gene coverage with copy number detection | Targeted Sanger sequencing (limited region, lower sensitivity) |
| Diagnostic Yield | >99% for point mutations & small indels | ~90% for known hotspots only |
| Turnaround Time | 3–4 Weeks (detailed clinical report) | 4–6 Weeks (often without CNV analysis) |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Genetics specialist, I recognize that this NGS test provides molecular clarity for a complex syndrome. The result must always be interpreted alongside a thorough dermatological, immunological, and bone health evaluation, as well as a detailed family pedigree obtained during pre-test genetic counselling. Clinical correlation is mandatory. Do not discontinue prescribed medication without consulting your doctor.” — Lina Osama Zaki Quteineh, DHA: 9294403
Advisory Recommendations
Critical Safety Advisory
- Pre-Test Requirement: A clinical history and a genetic counselling session to draw a family pedigree chart are mandatory prior to sample collection. This ensures accurate interpretation and UAE regulatory compliance.
- Informed Consent: Must be obtained as per Federal Decree-Law No. 4 of 2016 on Medical Liability.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide informed consent; active bleeding disorder not cleared for phlebotomy; minors without legal guardian accompaniment and consent.
- ER Red Flags: If you experience severe photosensitivity rash, sudden signs of systemic infection (fever, lymphadenopathy) due to immunodeficiency, or unexpected bone fractures, seek immediate medical attention.
Patient FAQ & Clinical Guidance
1. What is the purpose of the ERCC3 gene NGS test?
This NGS test confirms Trichothiodystrophy by detecting ERCC3 gene mutations at 99.9% accuracy. The assay sequences all coding exons and splice junctions, revealing point mutations, small insertions/deletions, and copy-number variations to establish a molecular diagnosis that guides dermatological, immunological, and orthopedic surveillance.
2. How is the sample collected for this genetic test?
A DHA-certified phlebotomist performs a painless home blood draw or accepts pre-extracted DNA, with cold-chain transport. We accept a whole blood EDTA sample, one drop of blood on an FTA card, or previously purified DNA, ensuring stability throughout our ISO‑certified logistics chain.
3. Is this ERCC3 test covered by insurance in the UAE?
We verify direct billing with major UAE insurers via WhatsApp; most plans cover this medically necessary genetic test. Send your insurance card copy to +971 54 548 8731 and we confirm coverage within 2 hours, so you can proceed with a pre‑approved pre‑counselling session.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: This test and all related processes operate under the DHA Facility License No. 1143, adhering to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent is obtained in accordance with Federal Decree-Law No. 4 of 2016 on Medical Liability.
All genetic data is encrypted, stored securely, and never shared without explicit written consent. DNA Labs UAE maintains ISO 9001:2015 certification (Cert: INT/EGQ/2509DA/3139) for quality management.
Clinical & Logistical Metadata
| Test Name | ERCC3 Gene Trichothiodystrophy Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card) |
| Methodology Used | Next-Generation Sequencing (NGS) – full gene coverage with CNV detection |
| ICD-10-CM Code | Q87.1, Z15.09, Q82.8 |
| LOINC Code | 55182-4 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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