Test Price
2,800 AED✅ Home Collection Available
ELN Gene Supravalvar Aortic Stenosis Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين ELN لتضيق الأبهر فوق الصمامي في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary / ملخص تنفيذي
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection and VIP Mobile Phlebotomy.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
الدقة المضمونة: حساسية تشخيصية 99.9% عبر معالجة معتمدة من ISO. الخدمات اللوجستية المتميزة: جمع عينة منزلية معتمدة من ISO بمواصفات سلسلة التبريد وخدمة الفصد المتنقل VIP. التوجيه الطبي: استشارة هاتفية ما بعد الاختبار لتفسير النتائج. التأمين: التحقق المباشر من التأمين عبر واتساب على الرقم +971 54 548 8731.
Regulatory Compliance & Accreditation: This test is performed in an ISO 9001:2015 certified laboratory (Cert: INT/EGQ/2509DA/3139) and strictly adheres to UAE Federal Decree-Law No. 41 of 2024 (Art. 87), CDS Law 2026 for minors, and UAE PDPL data privacy mandates. DHA-licensed clinical oversight guarantees E-E-A-T standards.
Clinical Overview & Test Comparison
The ELN Gene Supravalvar Aortic Stenosis Genetic Test detects pathogenic variants in the ELN gene responsible for supravalvular aortic stenosis (SVAS), Williams syndrome, and related connective tissue disorders. By utilizing Next Generation Sequencing (NGS) with comprehensive coverage of coding regions, this assay delivers a definitive molecular diagnosis essential for cardiological management, genetic counseling, and familial risk assessment.
| Feature | Our NGS Test (ELN Full Gene) | Conventional Sanger Sequencing |
|---|---|---|
| Detection Precision | 99.9% analytical sensitivity; covers all exons, intron-exon boundaries | Limited to known mutation hotspots; may miss large deletions |
| Methodology | Illumina NovaSeq X NGS, 100x depth, GRCh38 alignment, ACMG variant classification | Sanger sequencing, limited multiplexing |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks (smaller scope) |
LOINC code: 94745-7 | ICD‑10‑CM: Q25.3, Z15.89, Z13.79
Physician Insight & Safety Protocol
“As a practicing cardiologist, I know that an ELN genetic diagnosis can bring clarity and a clear path for monitoring. However, this test must always be correlated with echocardiograms and clinical evaluation. Please never discontinue any prescribed heart medication without direct medical advice.” — Dr. PRABHAKAR REDDY, DHA License 61713011
Safety Exclusion & Emergency Red Flags
- Exclusion Criteria: Minors without legal guardian consent (CDS Federal Law 2026); inability to provide blood/DNA sample; non‑adherence to mandatory pre‑test genetic counseling and pedigree charting.
- Emergency Red Flags: This is a non‑urgent genetic test. If you experience acute chest pain, severe dyspnea, syncope, or signs of a cardiac emergency, proceed immediately to the nearest emergency department — do not wait for test results.
Pre‑Test Requirements
A detailed clinical history and a mandatory genetic counseling session are required. The counselor will draw a pedigree chart documenting family members affected by ELN‑related conditions. No fasting or medication stoppage is needed unless advised by your physician. Sample options: whole blood (EDTA tube), extracted DNA, or one drop of blood on an FTA card. Home collection available 8 AM–11 PM.
Patient FAQ & Clinical Guidance
1. What conditions does the ELN gene test detect?
This test identifies pathogenic variants in the ELN gene linked to supravalvular aortic stenosis, Williams syndrome, and cutis laxa. It guides cardiology follow‑up, surgical planning, and family screening.
يكشف هذا الاختبار عن الطفرات المسببة لتضيق الأبهر فوق الصمامي، متلازمة ويليامز، ومرض الجلد المترهل، مما يوجه المتابعة القلبية والتخطيط الجراحي وفحص الأقارب.
2. How accurate is the Genetic Test?
With 99.9% analytical sensitivity, the NGS assay covers all ELN coding exons and splice sites using ISO‑accredited protocols, delivering a conclusive molecular result in 3–4 weeks.
بحساسية تحليلية تبلغ 99.9% وبروتوكولات معتمدة من ISO، يوفر تسلسل الجيل التالي تغطية كاملة للإكسونات، مع نتيجة جزيئية حاسمة خلال 3–4 أسابيع.
3. Why is genetic counseling required before this test?
Pre‑ counseling is mandatory to assess personal and family risk, draw a pedigree, and ensure informed consent in compliance with UAE genetic testing laws.
الاستشارة الوراثية إلزامية لتقييم المخاطر الشخصية والعائلية، ورسم شجرة العائلة، وضمان الموافقة المستنيرة وفق قوانين الفحوصات الجينية في الإمارات.
Support: +971 54 548 8731 (WhatsApp). Facility License No.: 9834453. All results interpreted by DHA‑licensed experts.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians