Test Price
2,800 AED✅ Home Collection Available
DUOX1 Gene Thyroid Dyshormonogenesis Type 6 Genetic Test at DNA Labs UAE | 2800 AED
Executive Summary & Core Metrics
99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS Processing (Cert: INT/EGQ/2509DA/3139), achieving analytical depth covering all DUOX1 coding exons ±20 bp intronic boundaries.
VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection. Blood (3 mL EDTA), Extracted DNA, or FTA Card accepted; available daily from 8 AM to 11 PM.
Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed Consultant Medical Geneticist (Dr. Lina Osama Zaki Quteineh, DHA 9294403) at no extra cost.
Direct Billing Verification via WhatsApp +971 54 548 8731. Most UAE payers accepted under applicable health insurance regulations.
Test Overview & Methodology
This Next-Generation Sequencing (NGS) test analyses the entire coding region of the DUOX1 gene to detect pathogenic variants causing thyroid dyshormonogenesis type 6, a rare autosomal recessive form of congenital hypothyroidism. The test provides early molecular diagnosis and enables tailored clinical management for neonates and adults in the UAE, following rigorous DHA-approved protocols.
| Feature | Our Test | Closest Alternative |
|---|---|---|
| Precision | NGS with >1000× mean read depth, all DUOX1 exons | Sanger sequencing (single gene, lower throughput) |
| Method | Illumina NovaSeq 6000, ISO 15189 validated | Capillary electrophoresis (older platform) |
| Turnaround | 3 to 4 Weeks with express 14‑day option | 4 to 6 Weeks typical |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Geneticist, I emphasize that a positive DUOX1 result must be correlated with newborn screening TSH levels and thyroid ultrasound; a negative result does not exclude other genetic or acquired causes of hypothyroidism. This test is a diagnostic tool and should be interpreted in conjunction with clinical evaluation and lifelong endocrinology follow-up.”
— Dr. Lina Osama Zaki Quteineh, DHA License 9294403
Medication Advisory
⚠ Important Medication Safety
Do not discontinue prescribed levothyroxine or any other medication without consulting your treating physician. Alterations may precipitate myxedema crisis, especially in infants. Always carry a list of current medications to your appointment.
Exclusion Criteria & ER Red Flags
Emergency Signs – Seek Immediate Medical Attention
- Neonatal respiratory distress, hypotonia, or open posterior fontanelle – seek emergency care before sample collection.
- Current anticoagulant therapy (except low‑dose aspirin) requires physician clearance for venipuncture.
- Known anaphylaxis to latex or antiseptic – alert the phlebotomist; we use latex‑free kits.
- If you experience sudden weight gain, extreme fatigue, or periorbital edema while awaiting results, visit the nearest ER immediately.
Patient FAQ & Clinical Guidance
1. Why should I choose this DUOX1 NGS test over a standard newborn TSH screening?
This test directly sequences the DUOX1 gene to identify the precise molecular cause of congenital hypothyroidism, enabling tailored treatment and family planning. While TSH screening detects hormone deficiency, it cannot distinguish transient versus permanent primary hypothyroidism or predict recurrence in future pregnancies. Our DHA‑guided protocol includes pre‑test genetic counselling and post‑test specialist review.
2. What genetic counseling is included with the test?
The test includes a comprehensive pre‑test genetic counseling session to review family history, discuss inheritance patterns, and assess recurrence risks. After results, a DHA-licensed geneticist provides a detailed interpretation explaining the clinical implications and any recommendations for family members. No fasting or medication changes are required.
3. Is my genetic data safe and compliant with UAE laws?
Absolutely. All samples are processed in a DHA‑licensed molecular lab under strict adherence to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Genetic data is encrypted, anonymized, and never shared without consent.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number 1143 and adheres to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL), Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, and Federal Decree-Law No. 4 of 2016 on Medical Liability. All genetic data is processed with strict confidentiality and security measures, ensuring compliance with the highest standards of patient privacy.
Clinical & Logistical Metadata
| Test Name | DUOX1 Gene Thyroid Dyshormonogenesis Type 6 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks (express 14‑day option available) |
| Sample Type / Matrix | Peripheral Blood (3 mL EDTA), Extracted DNA, or FTA Card |
| Methodology Used | Next‑Generation Sequencing (NGS) – Illumina NovaSeq 6000, ISO 15189 validated |
| ICD-10-CM Code | E07.1 Dyshormogenetic goiter; E03.1 Congenital hypothyroidism, unspecified; Z13.29 Encounter for screening for other suspected endocrine disorder |
| LOINC Code | 86234-4 DUOX1 gene mutations found [Identifier] in Blood or Tissue by Molecular genetics method |
| DHA Facility License & Laboratory Address | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DHA License 1143) |
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