Test Price
2,800 AED✅ Home Collection Available
DPAGT1 Gene Congenital Disorder of Glycosylation Type 1J (CDG‑Ij) Genetic Test in UAE – 2800 AED – DNA Labs UAE
Pinpoint the genetic cause of CDG‑Ij with 99.9% diagnostic sensitivity. NGS sequencing of the DPAGT1 gene, UAE‑approved home collection, and ISO‑certified excellence.
Executive Summary & Core Metrics
- ✓ Diagnostic Precision: 99.9% sensitivity via NGS sequencing of the full DPAGT1 coding region in an ISO 9001:2015 certified laboratory.
- ✓ VIP Home Collection: Temperature‑controlled cold‑chain phlebotomy available daily from 8 AM to 11 PM across Dubai and the UAE.
- ✓ Clinical Oversight: Post‑result telephone consultation with a Consultant Medical Geneticist for variant interpretation and family counselling.
- ✓ Insurance Facilitation: Direct billing verification via WhatsApp at +971 54 548 8731 prior to sample collection.
Test Overview & Methodology
This Next‑Generation Sequencing (NGS) test interrogates the entire coding region and splice junctions of the DPAGT1 gene to confirm or exclude Congenital Disorder of Glycosylation Type 1J (CDG‑Ij). This rare autosomal recessive disorder results in deficient dolichyl‑phosphate N‑acetylglucosaminephosphotransferase activity, leading to severe neurological impairment, psychomotor regression, and epileptic encephalopathy. Molecular confirmation enables precise prognostication, targeted supportive care, and informed reproductive planning.
| Feature | Our DPAGT1 NGS Test | Closest Alternative (Biochemical CDG Screening) |
|---|---|---|
| Precision | Mutation‑level resolution (DNA sequencing) | Pattern‑based (serum transferrin IEF) |
| Method | NGS – 100% target region coverage | Isoelectric Focusing / Mass Spectrometry |
| Turnaround | 3–4 weeks | 5–7 days |
| Clinical Value | Definitive molecular diagnosis, family planning | Screening only; requires genetic confirmation |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics – DHA Registration ID: 9294403:
Families facing unexplained neurological regression in a child carry an immense emotional burden. The DPAGT1 NGS test provides a definitive molecular answer, distinguishing CDG‑Ij from other metabolic encephalopathies and guiding a tailored management plan. I emphasise that all genetic findings must be interpreted within the full clinical context and never used in isolation for treatment decisions.
Advisory – Medication and Clinical Precautions
⚠️ Critical Clinical Advisory
Do not stop, alter, or initiate any prescribed therapy – including anti‑epileptic drugs, metabolic supplements, or dietary modifications – without prior discussion with your supervising physician. Abrupt changes may precipitate metabolic crisis or seizure exacerbation.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion: Individuals with a confirmed CDG diagnosis established by enzymatic assay who do not require molecular confirmation for clinical management should not proceed without explicit geneticist approval.
- Exclusion: Acute febrile illness or active metabolic crisis – reschedule collection once clinical stability is achieved.
- Emergency Red Flag: If during home collection you experience new‑onset seizures, loss of consciousness, severe hypoglycaemia, or respiratory distress, call 998 or proceed to the nearest emergency department immediately.
Patient FAQ & Clinical Guidance
1. What is the DPAGT1 gene test and what does it diagnose?
This test sequences the DPAGT1 gene to definitively diagnose congenital disorder of glycosylation type Ij (CDG‑Ij), a rare neurometabolic disease characterised by psychomotor regression, seizures, and neurological decline. Molecular confirmation distinguishes CDG‑Ij from other metabolic mimics and enables precise clinical management.
2. How is the test performed and what sample is required?
A standard peripheral whole blood sample is collected by a certified phlebotomist during a scheduled home visit. The blood is stabilised on an FTA card or in EDTA tubes and transported under temperature‑controlled cold‑chain conditions to our ISO‑certified laboratory for NGS analysis.
3. What is the turnaround time and cost, and is insurance accepted?
Results are delivered within 3 to 4 weeks. The total cost is 2800 AED. We facilitate direct insurance billing verification via WhatsApp at +971 54 548 8731 prior to sample collection to confirm coverage.
UAE Regulatory & Data Privacy Adherence
- Licensed by the Dubai Health Authority under facility license number 1143 – fully compliant with DHA regulatory standards for diagnostic genetic testing.
- All clinical data handled in accordance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields.
- Patient safety and informed consent protocols conform to Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- ISO 9001:2015 certified laboratory (Cert: INT/EGQ/2509DA/3139) – consistent quality management and continuous process improvement.
- Test methodology and clinical reporting align with international guidelines for molecular genetic diagnosis of congenital disorders of glycosylation.
Clinical & Logistical Metadata
| Test Name | DPAGT1 Gene Sequencing – Congenital Disorder of Glycosylation Type 1J (CDG‑Ij) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood (EDTA or FTA card) – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next‑Generation Sequencing (NGS) – full coding region and splice junctions of DPAGT1 |
| ICD-10-CM Code | E77.8 (Other disorders of glycoprotein metabolism) |
| LOINC Code | 21636-6 (Gene mutations identified [Identifier] in Blood or Tissue by Molecular genetics method) |
| DHA Facility License & Laboratory Address | DHA Facility License Number: 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE – DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians