Test Price
2,800 AEDโ Home Collection Available
CTC1 Gene Sequencing (Coat Plus Syndrome) Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
Executive Summary
99.9% diagnostic sensitivity via ISO 9001:2015 accredited NGS processing (Cert: INT/EGQ/2509DA/3139). VIP mobile phlebotomy & temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM. Post-test telephonic clinical guidance included. Price: 2,800 AED inclusive of genetic counselling session and comprehensive clinical report. Insurance & direct billing support via WhatsApp +971 54 548 8731. DHA Facility License No. 1143.
Test Overview & Methodology
The CTC1 Gene NGS Test analyzes the entire coding sequence of the CTC1 gene using Next Generation Sequencing to diagnose Coat Plus syndrome (cerebroretinal microangiopathy with calcifications and cysts โ CRMCC) and related telomere biology disorders. This definitive genetic assay identifies pathogenic variants with 99.9% sensitivity, guiding ophthalmologic, neurological, and systemic management for families across the UAE.
| Feature | Our Test (Premium) | Closest Alternative |
|---|---|---|
| Methodology | NGS (Next Generation Sequencing) โ full gene analysis | Sanger sequencing of select exons |
| Diagnostic Precision | 99.9% sensitivity, detects novel variants, CNVs | ~85% sensitivity, may miss deep intronic mutations |
| Turnaround Time | 3โ4 weeks with clinical interpretation | 4โ6 weeks |
| Regulatory Compliance | ISO 9001:2015, DHA/MOHAP licensed (Facility: 1143) | Variable |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA ID: 9294403) notes: โThis test provides crucial molecular confirmation for patients with retinal vascular anomalies, intracranial calcifications, or systemic features suggestive of CRMCC. Clinical correlation with a thorough ophthalmologic examination and neurological imaging remains essential; a negative result does not exclude all genetic etiologies. I strongly advise discussing results with a geneticist to integrate findings into a personalized care plan.โ
Advisory โ Medication & Clinical Context
Important Medical Advisory
Do not discontinue prescribed medication without consulting your doctor. This test is a diagnostic adjunct, not a substitute for clinical monitoring.
Exclusion Criteria & Red Flags
- Exclusion: Patients with active infection, coagulopathy (INR >1.5), or platelet count <50,000/ยตL require alternative sampling method (FTA card / extracted DNA).
- Red Flags: Sudden vision loss, acute intracranial hypertension, or new-onset seizures demand immediate emergency care, not a scheduled genetic test. Proceed only when medically stable.
- Pediatric Collection: For minors (<18 years), Federal Decree-Law No. 4 of 2016 on Medical Liability mandates legal guardian consent and a genetic counselling session prior to testing. Our team verifies compliance before appointment.
Patient FAQ & Clinical Guidance
1. How is the test performed and what sample types are accepted?
We require either a minimally invasive whole blood sample (4 mL EDTA tube), extracted DNA, or a single drop of blood on an FTA card. Our VIP mobile phlebotomist collects the sample at your home and transports it in a validated temperature-controlled cold-chain system to our ISO-certified lab. Home collection is available daily from 8 AM to 11 PM.
2. What preparation is needed before the test?
No fasting is required, but you must provide a detailed clinical history and attend a 30-minute genetic counselling session where a pedigree chart of affected family members will be drawn. This is mandatory for accurate result interpretation.
3. What do the results mean and who should interpret them?
A positive result confirms a diagnosis of Coat Plus syndrome with a specific pathogenic variant, enabling targeted surveillance for retinal, neurological, and systemic complications. Always review results with your ophthalmologist and a medical geneticist for comprehensive care planning.
UAE Regulatory & Data Privacy Adherence
This service operates in full compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 concerning the Use of Information and Communication Technology in Health Fields. All genetic data is securely stored and handled according to UAE healthcare regulations. Laboratory holds ISO 9001:2015 certificate INT/EGQ/2509DA/3139. Your privacy and data security are our highest priority.
Clinical & Logistical Metadata
| Test Name | CTC1 Gene Sequencing (Coat Plus Syndrome) Genetic Test |
| Price (AED) | 2,800 |
| Turnaround Time | 3โ4 weeks |
| Sample Type / Matrix | Whole Blood (EDTA), FTA card, or Extracted DNA |
| Methodology Used | NGS (Next Generation Sequencing) โ full gene analysis |
| ICD-10-CM Code | Q87.8 |
| LOINC Code | 81407-5 |
| DHA Facility License & Laboratory Address | DHA Facility License No. 1143 โ Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians