Test Price
2,800 AEDโ Home Collection Available
CR1 Gene Deficiency Genetic Test in UAE | 2800 AED | Accredited by DHA
Executive Summary & Core Metrics
Clinical Executive Summary
The CR1 Gene Deficiency Genetic Test employs Next-Generation Sequencing (NGS) to detect pathogenic variants in the complement receptor type 1 (CR1) gene, a critical factor in immune complex clearance and systemic lupus erythematosus (SLE) susceptibility. This molecular diagnostic provides definitive carrier and mutation status for complement receptor 1 deficiency.
- โ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified Processing.
- โ Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- โ Clinical Guidance: Telephonic Post-Test Clinical Interpretation by DHA-licensed genetics consultants.
- โ Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The CR1 Gene Deficiency Genetic Test utilizes NextโGeneration Sequencing (NGS) to screen for pathogenic variants in the complement receptor type 1 (CR1) gene. This advanced methodology delivers 99.9% sensitivity at the variant level, identifying exact mutations and carrier status for complement receptor 1 deficiency, a condition linked to increased risk of systemic lupus erythematosus (SLE) and immune complex clearance disorders.
| Feature | Our Test โ CR1 Gene NGS | Closest Alternative โ Complement Functional Panel (CH50/AH50) |
|---|---|---|
| Precision | 99.9% variant-level sensitivity; identifies exact mutation and carrier status | ~85% screening accuracy; cannot pinpoint genetic defect |
| Method | Next-Generation Sequencing (NGS) with bioinformatic filtering | Hemolytic assay (CH50 / AH50) |
| Speed | 3 โ 4 Weeks | 1 โ 2 Weeks |
Physician Insight & Safety Protocols
โAs a consultant in medical genetics, I emphasize that this CR1 NGS test provides definitive molecular evidence for complement receptor deficiency. However, clinical correlation with family history, complement protein levels, and autoimmune serology remains mandatory. A negative result does not exclude complement-mediated disease, and post-test genetic counselling is essential for integrating results into a comprehensive care strategy.โ
โ Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
โ ๏ธ Critical Advisory
Do not discontinue prescribed immunosuppressants, corticosteroids, or any medication without consulting your treating physician. Genetic test results are not a substitute for therapeutic decision-making and must be interpreted within the full clinical context.
Exclusion Criteria & Emergency Red Flags
- Sample Limitation: If you received a blood transfusion within 4 weeks, whole blood may not be suitable; an FTA card or extracted DNA sample is preferred.
- Paediatric Consent: Minors require guardian consent; genetic counselling session is mandatory before sample collection.
- ER Red Flags: Seek immediate emergency care if you experience sudden high fever, severe joint pain, new kidney dysfunction, or rapidly worsening lupus symptoms. This test does not replace urgent clinical evaluation.
Patient FAQ & Clinical Guidance
1. What is the CR1 gene NGS test and when is it recommended?
The CR1 NGS test is a definitive molecular diagnostic for detecting pathogenic variants in the CR1 gene that cause complement receptor 1 deficiency. It is recommended for patients with a family history of SLE, recurrent infections, or suspected complement deficiency based on abnormal CH50 levels.
2. How should I prepare for sample collection and what sample types are accepted?
You can provide a standard blood sample via VIP Mobile Phlebotomy (available 8 AM to 11 PM), extracted DNA, or a single drop of blood on an FTA card. A pre-test genetic counselling session is required to document family history and consent.
3. Will my health insurance cover the 2800 AED cost for this test in the UAE?
Many UAE insurers cover medically necessary genetic testing. Our team will verify your coverage via WhatsApp at +971 54 548 8731 before sample collection. Out-of-pocket payment options are also available.
4. What does a positive result mean for me and my family?
A positive result indicates a pathogenic variant in CR1, confirming complement receptor 1 deficiency. This may require family cascade testing and specialist follow-up for SLE management. Our post-test counselling team will guide you through the implications.
UAE Regulatory & Data Privacy Adherence
Regulatory Compliance: All clinical testing and patient consent procedures adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Data security and privacy protections follow Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Your genetic data remains confidential and is processed within ISO 9001:2015 certified frameworks.
Clinical & Logistical Metadata
| Test Name | CR1 Gene Deficiency Genetic Test (NGS) |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 โ 4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, Extracted DNA, or FTA Card |
| Methodology Used | Next-Generation Sequencing (NGS) |
| ICD-10-CM Code | D84.1 (Defects in the complement system) |
| LOINC Code | 51966-3 (Genetic analysis NGS gene panel) |
| DHA Facility License & Laboratory Address | License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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