Test Price
2,800 AED✅ Home Collection Available
COX6B1 Gene Mitochondrial Complex IV Deficiency Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% diagnostic sensitivity via ISO-accredited processing.
- Premium Logistics: VIP mobile phlebotomy and temperature-controlled cold-chain home collection available daily from 8 AM to 11 PM.
- Clinical Guidance: Telephonic post-test guidance for result interpretation by a specialist.
- Insurance: Direct billing verification via WhatsApp +971 54 548 8731.
This advanced NGS test detects pathogenic variants in the COX6B1 gene with 99.9% accuracy, aiding in the diagnosis of mitochondrial complex IV deficiency and related neurological disorders.
Test Overview & Methodology
This next‑generation sequencing (NGS) test provides complete coverage of the COX6B1 coding region, detecting single nucleotide variants, small insertions/deletions, and copy number variations. It offers superior precision compared to traditional Sanger sequencing.
| Feature | Our Test (NGS Panel) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Precision | ≥99.9% analytical sensitivity; SNVs, indels, CNVs | ~98% sensitivity; limited CNV detection |
| Method | Illumina NGS with 100% coding region coverage | Bidirectional Sanger sequencing of selected exons |
| Turnaround Time | 3 – 4 weeks | 4 – 6 weeks (typically) |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh, Consultant Medical Genetics (DHA ID: 9294403): “This NGS test is a critical tool for confirming mitochondrial complex IV deficiency. The genetic results must be interpreted alongside neuroimaging, metabolic markers, and family history, as some variants require functional validation. Do not modify any ongoing therapy based solely on this report without consulting your neurologist.”
Medical Advisory
Do not discontinue or alter prescribed medications, supplements, or dietary therapies without explicit guidance from your treating physician. Abrupt changes may exacerbate metabolic instability.
Exclusion Criteria & Emergency Red Flags
- Exclusion: Inability to provide informed consent; lack of a clinically indicated referral (e.g., isolated fatigue without neurological signs).
- ER Red Flags: Sudden onset of stroke‑like episodes, loss of vision, severe lactic acidosis (pH <7.2), acute muscle paralysis, or intractable seizures. Seek emergency care immediately.
Patient FAQ & Clinical Guidance
1. What is the COX6B1 gene and why is this test important?
The COX6B1 gene encodes a subunit of mitochondrial complex IV. Pathogenic variants cause severe neuro‑metabolic disorders, and this NGS test identifies those mutations with 99.9% sensitivity.
2. How is the sample collected and when do I get the results?
A simple blood draw (EDTA tube) or buccal swab is collected via our VIP mobile phlebotomy service in about 15 minutes. The comprehensive genomic report is delivered within 3 to 4 weeks.
3. Is this test covered by UAE health insurance?
Most UAE insurers cover medically necessary genetic testing for mitochondrial disorders. Our team will verify your policy and secure direct billing approval – contact us on WhatsApp +971 54 548 8731.
UAE Regulatory & Data Privacy Adherence
This test is performed in compliance with the Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical safety and patient consent follow Federal Decree-Law No. 4 of 2016 on Medical Liability. Your data is encrypted, anonymized, and never shared without explicit consent.
Clinical & Logistical Metadata
| Test Name | COX6B1 Gene Mitochondrial Complex IV Deficiency Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood (EDTA) or buccal swab; FTA card also accepted |
| Methodology Used | Next-Generation Sequencing (Illumina, 100% coding region coverage) |
| ICD-10-CM Code | E88.49 |
| LOINC Code | 81395-7 |
| DHA Facility License & Laboratory Address Invariants | DHA License No: 1143, DNA Labs UAE, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians