Test Price
2,800 AED✅ Home Collection Available
COG1 Gene Sequencing for Congenital Disorder of Glycosylation Type IIg (COG1-CDG) – NGS Genetic Test in UAE
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily from 8 AM to 11 PM across all UAE emirates.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation provided in English and Arabic.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test employs targeted Next-Generation Sequencing (NGS) to detect pathogenic variants in the COG1 gene, confirming congenital disorder of glycosylation type IIg (COG1-CDG). This rare multisystemic condition typically presents in infancy with developmental delay, failure to thrive, liver dysfunction, and coagulation abnormalities. Timely molecular diagnosis in the UAE empowers families with precise management strategies and access to specialised multidisciplinary care under DHA-endorsed protocols.
Why Choose Our COG1-CDG NGS Test?
| Feature | Our Test | Standard Alternative |
|---|---|---|
| Methodology | NGS with ACMG-guided variant interpretation and Sanger confirmation | Single‑gene Sanger only (limited coverage) |
| Turnaround Time | 3–4 Weeks | 6–8 weeks |
| Precision | 99.9% Diagnostic Sensitivity (ISO 9001:2015) | Variable, often without external quality assurance |
| Sample Type | Whole Blood, Extracted DNA, or Dried Blood Spot (FTA Card) | Whole Blood only |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics specialist, I emphasise that a genetic result is not a stand‑alone diagnosis; it must be interpreted alongside biochemical markers and clinical findings. Families often face a long diagnostic odyssey, and this test, when ordered appropriately, can bring clarity and hope. I strongly advise involving a Clinical Geneticist or Paediatric Metabolic Specialist to guide management and counselling.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Medication Advisory
⚠️ Important: Do not discontinue prescribed medication without consulting your doctor. Genetic results may influence treatment but never replace ongoing clinical care.
Exclusion Criteria & Emergency Red Flags
- Exclusion: This test is not suitable as a stand‑alone screen for unrelated conditions; patients with acute life‑threatening crises require immediate medical stabilisation before specimen collection.
- Red Flag Symptoms: Rapid neurological deterioration, uncontrolled seizures, or metabolic acidosis warrant emergency department evaluation — do not wait for genetic results.
- Minors: Genetic testing of minors follows UAE regulations; prior written consent from legal guardians and a genetic counselling session are mandatory.
Patient FAQ & Clinical Guidance
1. What is the COG1-CDG NGS test and who should consider it?
This NGS test identifies mutations in the COG1 gene causing congenital disorder of glycosylation type IIg, aiding definitive diagnosis for symptomatic individuals and carrier screening for at‑risk families. Children with developmental delay, failure to thrive, liver dysfunction, or coagulation abnormalities are typical candidates. Adults with mild phenotypes or a family history of unexplained infant deaths may also benefit. The test is ordered by a Clinical Geneticist, Paediatric Metabolic Specialist, or informed primary care physician after pre‑test counselling.
2. How is the sample collected and is home collection available?
A simple blood draw or dried blood spot card is collected, with VIP mobile phlebotomy and cold‑chain transport available across all UAE emirates. Our team follows ISO 9001:2015 protocols to maintain sample integrity from your doorstep to the laboratory. You can schedule a home visit between 8 AM and 11 PM, seven days a week. Dry blood spot samples are ideal for infants or when venous access is challenging, and they remain stable at room temperature for short periods.
3. What do the results mean and what support is provided?
A positive result confirms a diagnosis of COG1-CDG and opens access to targeted therapies, while a variant of uncertain significance requires expert correlation. All reports are reviewed by a board‑certified molecular geneticist and include a clinical interpretation. We offer post‑test telephonic guidance in English and Arabic to explain the findings and recommend further steps, such as referral to a metabolic specialist or family screening. Your data is protected under UAE PDPL, and results are shared only with your referring physician.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance Framework
All genetic data processed through this test is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Clinical testing safety and patient consent protocols adhere to Federal Decree-Law No. 4 of 2016 on Medical Liability. Your genomic information remains confidential and is only disclosed to the referring physician with your explicit consent.
Clinical & Logistical Metadata
| Test Name | COG1 Gene Sequencing for Congenital Disorder of Glycosylation Type IIg (COG1-CDG) – NGS |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (EDTA), Extracted DNA, or Dried Blood Spot (FTA Card) |
| Methodology Used | Targeted Next-Generation Sequencing (NGS) with ACMG variant interpretation and Sanger confirmation |
| ICD-10-CM Code | E77.8 |
| LOINC Code | 92807-0 |
| DHA Facility License & Laboratory Address | DHA License No: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians