Test Price
2,800 AED✅ Home Collection Available
CFHR4 Gene Hemolytic Uremic Syndrome (HUS) Genetic Test in UAE | 2,800 AED
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
This advanced genetic test sequences the entire CFHR4 gene using next-generation sequencing (NGS) to identify pathogenic variants linked to atypical hemolytic uremic syndrome (aHUS), a rare but severe thrombotic microangiopathy. In the UAE, our DHA-compliant service ensures confidential genetic counselling, ISO-certified sample logistics, and actionable results within 3–4 weeks.
| Feature | Our Test (NGS Full Gene Analysis) | Closest Alternative (Targeted Sanger Sequencing) |
|---|---|---|
| Methodology | NGS – comprehensive coverage of all exons and splice sites | Sanger sequencing of selected hotspots only |
| Variant Detection | >99.9% sensitivity for SNVs and small indels | ~80% sensitivity, may miss rare or novel mutations |
| Turnaround Time | 3–4 weeks | 2–3 weeks |
| Genetic Counselling | Mandatory pre- and post-test session included | Often optional or limited |
Physician Insight & Safety Protocols
“As a DHA-licensed Consultant Medical Genetics, I remind patients that a positive CFHR4 mutation indicates genetic susceptibility and requires correlation with renal function tests, complement levels, and family history. A negative result does not exclude aHUS if clinical suspicion remains high, as other complement genes may be involved. Please discuss all results with your nephrologist or geneticist before making any treatment decisions.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Medication Advisory
Do not discontinue prescribed medication (e.g., eculizumab, antihypertensives) without consulting your treating physician. Genetic test results should never be used to self-adjust therapy.
Patient Safety Exclusion Criteria & Emergency Red Flags
- Exclusion for home blood collection: Active systemic infection, severe hypotension, or current hospitalization for acute kidney injury.
- Do not proceed with genetic test if: Patient is unable to provide informed consent or lacks a legal guardian as required by Federal Decree-Law No. 4 of 2016 on Medical Liability.
- ER Red Flags: Sudden anuria, confusion, seizures, or severe abdominal pain may indicate acute HUS progression; seek immediate emergency care. This test is not for acute crisis diagnosis.
Patient FAQ & Clinical Guidance
1. What is the CFHR4 gene test for?
This NGS test identifies pathogenic variants in the CFHR4 gene that are associated with atypical hemolytic uremic syndrome, helping to confirm a genetic diagnosis and guide family screening.
2. How is the sample collected and what are the requirements?
A simple blood draw, extracted DNA, or a drop on an FTA card can be used; our VIP mobile phlebotomy service ensures home collection with cold-chain transport and mandatory pre-test genetic counselling.
3. Is this test covered by insurance in the UAE?
Many UAE insurers cover genetic testing for aHUS when medically necessary; we offer direct billing verification via WhatsApp at +971 54 548 8731 and will assist with pre-authorization.
UAE Regulatory & Data Privacy Adherence
All genetic data and personal information are handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Results are securely transmitted only to the ordering physician and the patient via encrypted channels. DNA Labs UAE is a DHA-licensed facility (License No. 1143) ensuring the highest standards of data privacy and security.
Clinical & Logistical Metadata
| Test Name | CFHR4 Gene Hemolytic Uremic Syndrome (HUS) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Whole blood, extracted DNA, or FTA card |
| Methodology Used | Next Generation Sequencing (NGS) – Full Gene Analysis |
| ICD-10-CM Code | D59.32 |
| LOINC Code | 81329-5 |
| DHA Facility License & Laboratory Address | License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | DNA Labs UAE |
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