Test Price
2,800 AED✅ Home Collection Available
CBFB Gene Skeletal Abnormalities Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection available daily 8 AM – 11 PM.
- Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
CBFB Gene Skeletal Abnormalities Genetic Test identifies pathogenic variants in the core‑binding factor beta subunit gene using Next‑Generation Sequencing, aiding the diagnosis of congenital skeletal dysplasias and dysmorphology.
| Parameter | Our Test – CBFB NGS | Closest Alternative |
|---|---|---|
| Precision | 99.9% Sensitivity, full gene coverage | Sanger sequencing may miss copy number variants |
| Method | Next‑Generation Sequencing (NGS) | Endpoint PCR / Sanger |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks, limited bioinformatics |
| Sample Options | Peripheral Whole Blood, Extracted DNA, One‑drop FTA Card | Blood only |
| Counselling | Pre‑ & Post‑Test Genetic Counselling Included | Often not included |
Physician Insight & Safety Protocols
"As a Consultant Medical Geneticist (DHA: 9294403), I emphasize that CBFB NGS results must be contextualized within a comprehensive dysmorphology assessment and three‑generation pedigree. A negative report does not exclude a clinical diagnosis, and all molecular findings require careful phenotype correlation."
— Lina Osama Zaki Quteineh, DHA‑Licensed Consultant Medical Genetics
Advisory Note: Medication and Test Dependency
⚠️ Do not discontinue prescribed medication without consulting your doctor. This genetic test is not a replacement for urgent clinical evaluation. Always follow your physician’s guidance regarding treatment modifications.
Exclusion Criteria & Emergency Red Flags
- Patients without a pre‑test genetic counselling session (pedigree drawing) cannot be processed under UAE Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Home collection is not performed if the patient presents acute respiratory distress, cyanosis, or uncontrolled seizure activity.
- Results should never be used in isolation to make surgical or therapeutic decisions; always seek specialist paediatric or geneticist input.
- Red Flags requiring immediate emergency care: rapid progression of limb deformity, severe feeding difficulties in neonates, acute bone pain with swelling, or suspected pathological fracture.
Patient FAQ & Clinical Guidance
1. What is the CBFB gene and why test for skeletal abnormalities?
Snippet: CBFB provides instructions for a protein that partners with RUNX transcription factors to control bone and cartilage development; mutations can cause skeletal dysplasias.
Testing via NGS identifies pathogenic variants across the entire coding region, enabling confirmation of a clinical diagnosis like cleidocranial dysplasia‑spectrum disorders, guiding treatment and family planning.
2. How is the NGS test performed and what sample is needed?
Snippet: A simple blood draw, a drop of blood on FTA card, or previously extracted DNA is all that is required for the test.
Our phlebotomy team collects the sample in your home using a cold‑chain protocol; the DNA is then sequenced with 100x depth to ensure reliable variant calling.
3. How long do results take and how will I receive them?
Snippet: Results are ready in 3 to 4 weeks, and a secure report is sent with telephonic post‑test guidance from our clinical team.
The final report includes variant interpretation according to ACMG guidelines, clinical correlation notes, and a scheduled call with a genetic counsellor to discuss implications.
UAE Regulatory & Data Privacy Adherence
This genetic test is performed in full compliance with Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All patient data is encrypted, access‑controlled, and handled strictly according to UAE data protection regulations. ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139). Results must be interpreted by a DHA‑licensed geneticist.
Clinical & Logistical Metadata
| Test Name | CBFB Gene Skeletal Abnormalities Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Peripheral Whole Blood, One‑drop FTA Card, Extracted DNA |
| Methodology Used | Next‑Generation Sequencing (NGS) |
| ICD-10-CM Code | Q78.8 |
| LOINC Code | 81247-9 |
| DHA Facility License & Address | License No. 1143, Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians