Test Price
2,800 AED✅ Home Collection Available
DHA-APPROVED GENOMICS · ISO 9001:2015
CALM1 Gene Catecholaminergic Polymorphic Ventricular Tachycardia Type 4 (CPVT4) Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين CALM1 لتسارع القلب البطيني متعدد الأشكال الكاتيكولاميني النوع 4 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
- 99.9% Diagnostic Sensitivity – ISO 15189–accredited NGS processing with clinical-grade variant calling.
- Premium Logistics – Paid hospital‑grade home collection via ISO‑certified cold‑chain transport and VIP mobile phlebotomy.
- Clinical Guidance – Complimentary telephonic post‑test clinical correlation session with our medical team.
- Insurance Support – Direct billing verification via WhatsApp +971 54 548 8731.
ملخص تنفيذي: فحص جيني متقدم بدقة تشخيصية 99.9%، يشمل الاستشارة الوراثية وسحب العينات في المنزل وفق أعلى معايير الجودة والخصوصية الإماراتية.
Overview
The CALM1 gene encodes calmodulin, a critical calcium‑signaling protein. Pathogenic variants cause catecholaminergic polymorphic ventricular tachycardia type 4 (CPVT4), a potentially lethal inherited arrhythmia. Our NGS‑based test sequences the entire coding region and exon‑intron boundaries of CALM1, offering definitive risk stratification.
| Feature | Our Test (NGS) | Sanger Sequencing Alternative |
|---|---|---|
| Method | Next‑Generation Sequencing (HiSeq) | Capillary electrophoresis (single amplicon) |
| Analytical Sensitivity | >99.9% for SNVs and small indels | ~99% (limited to predefined region) |
| Turnaround Time | 3–4 Weeks | 5–7 business days (incomplete coverage) |
| Clinical Utility | Full gene plus adjacent regions, ACMG/AMP classification | Known familial variant only |
Physician Insight & Safety Protocol
“As a clinical cardiologist, I emphasise that genetic testing for CPVT is not a standalone diagnosis—it must be interpreted alongside a comprehensive clinical evaluation, electrocardiographic findings, and family history. A negative result does not exclude the condition, and a variant of uncertain significance should never drive clinical decisions without expert multidisciplinary review.”
— Dr. PRABHAKAR REDDY, Consultant Cardiologist, DHA License 61713011
Medication Warning
Do not discontinue or modify prescribed antiarrhythmic medications, beta‑blockers, or any other cardiac therapy without explicit instruction from your treating physician. Genetic results must never be used to self‑adjust treatment.
Exclusion Criteria & ER Red Flags
- Individuals who have undergone allogeneic bone marrow transplant within the last six months (donor DNA interference).
- Patients in active hemodynamic instability or ongoing cardiac arrest.
- Inability to provide informed consent (legal guardian must authorise for minors).
- Emergency warning: If you experience syncope, chest pain, or sustained palpitations, seek immediate emergency medical attention; do not wait for genetic test results.
Patient FAQ & Clinical Guidance
Q1: Why do I need this genetic test if I already have a clinical diagnosis?
The CALM1 NGS test identifies the exact pathogenic variant underlying your catecholaminergic polymorphic ventricular tachycardia, enabling precision risk stratification and family cascade screening. يحدد اختبار جين CALM1 الطفرة المسببة بدقة مما يتيح فحص أفراد العائلة وتقدير الخطر الفردي بدقة عالية.
Q2: Is the sample collection painful, and how should I prepare?
Our VIP mobile phlebotomist uses a single venipuncture for whole blood (or buccal swab/FTA card); discomfort is minimal, and no fasting or medication change is required. سحب العينة سريع وغير مؤلم، ولا يتطلب أي تحضيرات خاصة أو تغيير للأدوية.
Q3: What happens after the result is reported?
You receive a comprehensive ACMG‑classified report and a telephonic post‑ clinical guidance session to integrate findings with your cardiologist’s management plan. ستتلقى تقريراً مفصّلاً وجلسة إرشاد سريري هاتفية للمساعدة في دمج النتائج مع خطة العلاج.
Federal Decree-Law No. 41 of 2024 (Art. 87) · CDS Law 2026 (Minors) · UAE PDPL · ISO 9001:2015 Certified (Cert: INT/EGQ/2509DA/3139) · DHA Facility License 9834453
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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All reports reviewed by DHA-Certified physicians