Test Price
2,800 AED✅ Home Collection Available
ATL3 Gene Hereditary Sensory Neuropathy Type 1F (HSN1F) Genetic Test in the UAE
2800 AED
Executive Summary & Core Metrics
This comprehensive genetic test provides full sequencing of the ATL3 gene using next‑generation technology, delivering 99.9% diagnostic sensitivity for hereditary sensory neuropathy type 1F in compliance with UAE regulatory standards.
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Accredited Processing.
- Premium Logistics: VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection (Daily 8 AM–11 PM).
- Clinical Guidance: Telephonic Post‑Test Genetic Counselling and interpretation session.
- Insurance: Direct Billing Verification via WhatsApp +971 54 548 8731.
Test Overview & Methodology
The ATL3 Gene Hereditary Sensory Neuropathy Type 1F Genetic Test is the most definitive diagnostic tool for detecting pathogenic variants in the ATL3 gene, responsible for autosomal dominant sensory neuropathy with progressive loss of pain, temperature, and touch sensation. Our method uses next‑generation sequencing (NGS) covering the entire coding region plus ±5 bp flanking intronic sequences, followed by Sanger confirmation of all clinically significant variants. This achieves a diagnostic sensitivity exceeding 99.9% and a turnaround time of 3 to 4 weeks with full clinical interpretation.
| Feature | Our Test (UAE Genetic Diagnostics) | Closest Alternative (Standard Single‑Gene Test) |
|---|---|---|
| Precision | Full ATL3 gene coverage (±5 bp flanking) with >100x depth | Limited to known “hotspot” exons only |
| Method | NGS + Sanger confirmation of all clinically significant variants | Sanger sequencing of selected regions |
| Turnaround Time | 3 to 4 weeks with detailed clinical interpretation | 6 to 8 weeks |
| Regulatory Compliance | DHA Licensed, ISO 9001:2015, UAE PDPL (Federal Decree‑Law No. 45 of 2021), Federal Law No. 2 of 2019 | Often lacks DHA‑specific genetic testing oversight |
Physician Insight & Safety Protocols
“As a consultant in medical genetics, I emphasize that the ATL3 gene test delivers near‑absolute diagnostic clarity. However, results must always be correlated with the full clinical picture. A negative result does not exclude other hereditary neuropathies, and a positive finding requires compassionate genetic counselling and multidisciplinary follow‑up. This test is an elective diagnostic tool, not an emergency intervention.”
— Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
Advisory for Medication Management
⚠️ Do not discontinue prescribed medication without consulting your doctor. Abrupt withdrawal of neuropathic pain agents (e.g., gabapentinoids, antidepressants) can provoke severe symptoms.
Safety & Exclusion Criteria
- Inability to consent: For minors or patients lacking capacity, legal guardian consent is mandatory per Federal Decree‑Law No. 4 of 2016 on Medical Liability.
- Life‑threatening emergency: This is an elective genetic test; any acute neurological crisis (e.g., stroke‑like episode) must be managed at the nearest emergency department before sample collection.
- Prior major blood product transfusion within 90 days: May affect DNA purity from whole blood; use buccal swab or extracted DNA with counsellor’s approval.
ER Red Flags – Seek Immediate Medical Attention:
- Sudden worsening of numbness or weakness
- Unexplained falls, joint injuries, or burns due to sensory loss
- Any sign of new autonomic dysfunction (e.g., orthostatic dizziness, bladder retention)
Patient FAQ & Clinical Guidance
1. What is the diagnostic sensitivity of the ATL3 gene test and how does it compare to clinical diagnosis alone?
The NGS‑based ATL3 gene analysis offers 99.9% diagnostic sensitivity for identifying pathogenic variants, compared to approximately 60% accuracy from clinical signs, which are often subtle in early stages.
2. Will my insurance cover the 2800 AED cost and can I pay after DHA approval?
Direct billing is available for most UAE insurers; submit your Emirates ID and insurance card via WhatsApp to +971545488731 for instant pre‑approval verification before sample collection.
3. How should I prepare for the test and what happens after I receive my results?
Fasting is not required; simply maintain your usual routine and attend the genetic counselling session where a pedigree will be drawn prior to phlebotomy – then a telephonic interpretation conference with a specialist will be scheduled post‑result.
UAE Regulatory & Data Privacy Adherence
Your data is protected under:
- Federal Decree‑Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring strict handling, storage, and processing of genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing the security of electronic health records and genetic test results.
- Federal Decree‑Law No. 4 of 2016 on Medical Liability – providing the legal framework for informed consent and clinical responsibility in genetic testing.
Clinical & Logistical Metadata
| Test Name | ATL3 Gene Hereditary Sensory Neuropathy Type 1F (HSN1F) Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3 to 4 weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted DNA, or FTA card – VIP Mobile Phlebotomy & Temperature‑Controlled Cold‑Chain Home Collection available daily 8 AM–11 PM |
| Methodology Used | Next‑Generation Sequencing (NGS) + Sanger confirmation |
| ICD-10-CM Code | G60.8 |
| LOINC Code | 82287-9 |
| DHA Facility License & Laboratory Address | License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE (DNA Labs UAE) |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians