Test Price
2,800 AED✅ Home Collection Available
ALX4 Gene Parietal Foramina Type 2 Genetic Test in UAE | 2800 AED | DHA Licensed
Executive Summary & Core Metrics
- Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Accredited Processing (Cert: INT/EGQ/2509DA/3139).
- Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM).
- Clinical Guidance: Post-test correlation with DHA-licensed Consultant Medical Genetics (telephonic support included).
- Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Test Overview & Methodology
This Next-Generation Sequencing (NGS) test analyzes the entire coding region and splice sites of the ALX4 gene to detect pathogenic mutations responsible for parietal foramina type 2 (PFM2). PFM2 is a rare autosomal dominant condition characterized by symmetrical oval defects in the parietal bones. The test is performed in our ISO 9001:2015 accredited laboratory under strict DHA guidelines, ensuring clinical-grade accuracy for Emirati and expatriate families seeking definitive diagnosis or reproductive risk assessment.
| Feature | ALX4 NGS Test (Our Laboratory) | Standard Sanger Sequencing |
|---|---|---|
| Analytical Sensitivity | >99.9% (full gene coverage including exons, intronic boundaries, and splice sites) | ~90% (targets known variants only) |
| Methodology | Illumina NGS with bioinformatic validation, ISO 9001:2015 (Cert: INT/EGQ/2509DA/3139) | Chain-termination (Sanger) sequencing |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks |
| Sample Requirement | Whole blood (EDTA), extracted DNA, or FTA card spot – home collection available | Whole blood only – clinic visit required |
Physician Insight & Safety Protocols
“As a Consultant Medical Genetics, I emphasize that this test identifies pathogenic variants in ALX4 linked to parietal foramina type 2. While often a benign radiological finding, it can occasionally be associated with intracranial hypertension or developmental delay. Results should be interpreted in conjunction with clinical evaluation, family history, and imaging. I strongly recommend discussing findings with a neurologist or genetic counselor before making any medical decisions.”
– Lina Osama Zaki Quteineh, Consultant Medical Genetics | DHA Registration ID: 9294403
⚠️ Advisory: Genetic Testing & Medication
Do not discontinue prescribed medication without consulting your doctor. Genetic information is a risk stratification tool and does not replace ongoing medical care. Always communicate your test results with your treating physician for coordinated management.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Acute febrile illness, severe anemia, coagulation disorders (if blood draw), inability to provide informed consent (for minors, compliance with Federal Decree-Law No. 4 of 2016).
- ER Red Flags – Seek Immediate Medical Attention if: Sudden severe headache, vision changes, seizures, or loss of consciousness appear after testing.
Patient FAQ & Clinical Guidance
1. What is the ALX4 Gene Parietal Foramina Type 2 test, and why is it relevant in the UAE?
This genetic test detects mutations in the ALX4 gene that cause parietal foramina type 2 (PFM2), a condition involving congenital openings in the skull. It is used for definitive diagnosis, family screening, and reproductive planning. The test is performed under DHA guidelines and is available to both Emirati and expatriate families.
2. How is the sample collected, and what is the turnaround time?
A standard blood draw or FTA card spot is collected at your home by a DHA-licensed phlebotomist (VIP Mobile Phlebotomy, 8 AM–11 PM). Results are delivered within 3–4 weeks from sample receipt in the laboratory.
3. Is this test covered by UAE health insurance?
Many UAE insurers cover genetic testing with prior approval. Verify your eligibility and direct billing options by sending a WhatsApp message to +971 54 548 8731 for instant confirmation.
UAE Regulatory & Data Privacy Adherence
DNA Labs UAE operates under DHA Facility License Number: 1143 and complies fully with:
- Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) – ensuring secure handling of genetic data.
- Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields – governing health information systems.
- Federal Decree-Law No. 4 of 2016 on Medical Liability – regulating patient consent and clinical safety.
All genetic testing is processed in our ISO 9001:2015 accredited laboratory (Cert: INT/EGQ/2509DA/3139). Physical address: Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE.
Clinical & Logistical Metadata
| Test Name | ALX4 Gene Parietal Foramina Type 2 Genetic Test (Full Gene Sequencing) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole blood (EDTA), extracted genomic DNA, or dried blood spot on FTA card – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (daily 8 AM–11 PM) |
| Methodology Used | Next-Generation Sequencing (NGS) – Illumina platform; bioinformatic analysis for SNVs, indels, and splice site variants |
| ICD-10-CM Code | Q75.8 |
| LOINC Code | 81247-9 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 – Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE |
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