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COMT Genotyping Test Cost

Original price was: 9,600 د.إ.Current price is: 7,200 د.إ.

-25%

The COMT Genotyping Test is a specialized diagnostic procedure offered by DNA Labs UAE, designed to analyze the catechol-O-methyltransferase (COMT) gene. This gene plays a critical role in the metabolism of catecholamines, such as dopamine, epinephrine, and norepinephrine, which are crucial for various bodily functions including mood regulation, cognition, and stress response. By examining the COMT gene, this test can help in understanding an individual’s genetic predisposition to certain mental health conditions, including depression, anxiety, and schizophrenia, as well as their response to certain medications.

The test involves collecting a DNA sample, usually through a simple and non-invasive method like a saliva swab or a blood sample. The sample is then analyzed to identify variations or mutations in the COMT gene that may affect the enzyme’s activity level. Understanding these genetic variations can be particularly useful in personalized medicine, allowing healthcare providers to tailor treatment plans for mental health conditions more effectively.

At DNA Labs UAE, the COMT Genotyping Test is priced at 7200 AED. This cost reflects the comprehensive analysis and the personalized insights provided, which can be invaluable in managing and understanding an individual’s mental health and wellbeing.

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  • This test is not intended for medical diagnosis or treatment
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COMT GENOTYPING Test – Cost, Symptoms, Diagnosis

At DNA Labs UAE, we offer the COMT genotyping test at a cost of AED 7200.0. This genetic test analyzes the DNA of an individual to determine their COMT genotype.

Test Details

The COMT genotyping test is a genetic test that analyzes the DNA of an individual to determine their COMT genotype. COMT (catechol-O-methyltransferase) is an enzyme that plays a crucial role in the breakdown of certain neurotransmitters, including dopamine, norepinephrine, and epinephrine.

The COMT gene has several variations, or polymorphisms, that can affect the activity of the COMT enzyme. The most well-known polymorphism is the Val158Met polymorphism, which results in a change in the amino acid sequence of the COMT enzyme.

Individuals with the Val/Val genotype have a higher activity of the COMT enzyme, which leads to a faster breakdown of neurotransmitters. On the other hand, individuals with the Met/Met genotype have a lower activity of the COMT enzyme, which leads to a slower breakdown of neurotransmitters. Individuals with the Val/Met genotype have an intermediate activity of the COMT enzyme.

Symptoms and Diagnosis

The COMT genotyping test can be useful in several contexts, including personalized medicine, pharmacogenomics, and psychiatric research. For example, individuals with the Val/Val genotype may have a higher risk of developing anxiety and depression, while individuals with the Met/Met genotype may have a higher risk of developing schizophrenia.

The COMT genotype can also affect the response to certain medications, such as antipsychotics and antidepressants. Therefore, knowing an individual’s COMT genotype can help guide personalized treatment plans.

Test Process and Cost

The COMT genotyping test requires a sample of 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. The sample should be shipped refrigerated and should not be frozen. A duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory for the test.

The test is performed using PCR sequencing method and falls under the category of Pharmacogenomics. It is carried out in our Molecular Diagnostics department.

The cost of the COMT genotyping test is AED 7200.0. The report is delivered within 10 working days, with the sample required to be submitted by 11 am on SampleSat.

Referred Doctors

The COMT genotyping test can be requested by physicians, neurologists, and psychiatrists.

Overall, the COMT genotyping test at DNA Labs UAE provides valuable information about an individual’s genetic makeup and can help guide personalized treatment plans.

Test Name COMT GENOTYPING Test
Components
Price 7200.0 AED
Sample Condition 4 mL (2 mL min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Report Delivery SampleSat by 11 am ; Report 10 Working days
Method PCR Sequencing
Test type Pharmacogenomics
Doctor Physician, Neurologist, Psychiatrist
Test Department: MOLECULAR DIAGNOSTICS
Pre Test Information Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory.
Test Details

The COMT genotyping test is a genetic test that analyzes the DNA of an individual to determine their COMT genotype. COMT (catechol-O-methyltransferase) is an enzyme that plays a crucial role in the breakdown of certain neurotransmitters, including dopamine, norepinephrine, and epinephrine.

The COMT gene has several variations, or polymorphisms, that can affect the activity of the COMT enzyme. The most well-known polymorphism is the Val158Met polymorphism, which results in a change in the amino acid sequence of the COMT enzyme.

Individuals with the Val/Val genotype have a higher activity of the COMT enzyme, which leads to a faster breakdown of neurotransmitters. On the other hand, individuals with the Met/Met genotype have a lower activity of the COMT enzyme, which leads to a slower breakdown of neurotransmitters. Individuals with the Val/Met genotype have an intermediate activity of the COMT enzyme.

The COMT genotyping test can be useful in several contexts, including personalized medicine, pharmacogenomics, and psychiatric research. For example, individuals with the Val/Val genotype may have a higher risk of developing anxiety and depression, while individuals with the Met/Met genotype may have a higher risk of developing schizophrenia. The COMT genotype can also affect the response to certain medications, such as antipsychotics and antidepressants.

Overall, the COMT genotyping test can provide valuable information about an individual’s genetic makeup and can help guide personalized treatment plans.