Test Price
2,800 AED✅ Home Collection Available
CACNB2 Gene Brugada Syndrome Type 4 Genetic Test in Dubai, UAE | AED 2,800 | Premium NGS Panel
Executive Summary & Core Metrics
Executive Summary: This advanced genetic test provides 99.9% diagnostic sensitivity for pathogenic CACNB2 variants, processed in an ISO 9001:2015 certified facility. It includes hospital-grade home collection via cold-chain transport, VIP mobile phlebotomy, and post-test clinical guidance by DHA-licensed experts. Insurance coverage verification is available via WhatsApp at +971 54 548 8731. Turnaround time is 3–4 weeks from sample receipt.
Test Overview & Methodology
The CACNB2 NGS test deciphers the entire coding and splice regions of the CACNB2 gene, associated with Brugada syndrome type 4—a life-threatening sodium channelopathy predisposing to sudden cardiac arrest. Results guide targeted surveillance, pharmacological avoidance, and cascade family screening.
| Feature | Our Test – Premium DHA Package | Closest Alternative |
|---|---|---|
| Diagnostic Precision | 99.9% analytical sensitivity via triple-validated NGS | 85–90% with targeted PCR panels; miss deep intronic/regulatory mutations |
| Methodology | Next Generation Sequencing (NGS) with full gene coverage, including 5’/3’ UTR and exon-intron boundaries | Sanger sequencing or limited gene panels; often no coverage of non-coding variants |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks, with potential re-bleeds |
| Post-test Support | Free telephonic result interpretation by a cardiologist and genetic counselor | Report only; additional consultation not integrated |
Physician Insight & Safety Protocols
“A positive CACNB2 variant must be interpreted within a comprehensive cardiac evaluation—resting ECG, drug challenge, and family history—because genotype-phenotype correlation varies. Even a negative test does not exclude Brugada syndrome, as other genes may be involved. The report is a starting point for shared decision-making, not a standalone diagnosis.” — Lina Osama Zaki Quteineh, Consultant Medical Genetics, DHA Registration ID: 9294403
Advisory: Medication Continuity
⚠️ Do not discontinue prescribed medication without consulting your doctor.
Exclusion Criteria & Emergency Red Flags
Exclusion Criteria
- Inability to provide informed consent (guardian required for minors per Federal Decree-Law No. 4 of 2016 on Medical Liability).
- Acute febrile illness or active skin infection at venipuncture site.
- Suspected heparin-induced thrombocytopenia (if blood is the starting material).
🚨 Seek immediate emergency care if you experience: sudden collapse, unexplained syncope, seizure-like activity, nocturnal agonal respiration, or self-recognized type 1 Brugada ECG pattern—these may indicate high-risk arrhythmic events.
Patient FAQ & Clinical Guidance
1. What is the purpose of the CACNB2 Genetic Test?
A: The CACNB2 Genetic Test detects mutations in the CACNB2 gene to diagnose Brugada syndrome type 4, enabling early risk stratification and preventive measures against sudden cardiac death.
2. How is the sample collected and how long do results take?
A: A simple blood sample, extracted DNA, or a drop of blood on an FTA card is collected via home visit phlebotomy; results are delivered in 3–4 weeks with a comprehensive clinical report.
3. Is this test approved by UAE health authorities?
A: Yes, our facility is DHA-licensed (License No. 1143) and operates under ISO 9001:2015 certification, adhering to Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields, ensuring data privacy and clinical validity.
UAE Regulatory & Data Privacy Adherence
Data Protection & Compliance
All genetic data is handled in strict compliance with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. Patient consent and confidentiality are paramount, with secure storage and encrypted transmission. The laboratory holds DHA Facility License No. 1143 and operates under ISO 9001:2015 quality management.
Clinical & Logistical Metadata
| Test Name | CACNB2 Gene Brugada Syndrome Type 4 Genetic Test (NGS) |
| Price (AED) | 2,800 |
| Turnaround Time | 3–4 Weeks |
| Sample Type / Matrix | Whole Blood (Peripheral) – VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) |
| Methodology Used | Next Generation Sequencing (NGS) – Full gene coverage including 5’/3’ UTR and exon-intron boundaries |
| ICD-10-CM Code | I49.8 |
| LOINC Code | 48807-7 |
| DHA Facility License & Laboratory Address | DHA License: 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
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Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians