Test Price
2,800 AED✅ Home Collection Available
KCNE2 Gene Long QT Syndrome Type 6 Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين KCNE2 متلازمة كيو تي الطويلة النوع 6 في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
Executive Summary
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS processing, directly aligned with 2026 ACMG/AMP guidelines.
Premium Logistics: Paid Hospital‑Grade Home Collection using ISO‑Certified Cold‑Chain transport (8 AM‑11 PM) with VIP Mobile Phlebotomy.
Clinical Guidance: Post‑test telephonic interpretative session with a DHA‑licensed cardiologist to explain results and action plans.
Insurance: Direct billing verification via WhatsApp at +971 54 548 8731 – most UAE insurers accepted.
ملخص تنفيذي: يضمن مختبرنا المرخص من هيئة الصحة بدقة تشخيصية بنسبة 99.9% لتسلسل الجيل التالي لجين KCNE2، مع خدمة السحب المنزلي بسلسلة تبريد محكمة وجلسات إرشاد وراثي عبر الهاتف، كما نوفر التحقق المباشر للبطاقات التأمينية.
Diagnostic Overview & Methodology
This advanced Next‑Generation Sequencing (NGS) test screens all coding exons, splice junctions, and known deep intronic regions of the KCNE2 gene to detect pathogenic variants responsible for Long QT syndrome type 6. It delivers a definitive molecular diagnosis that guides prophylactic beta‑blocker therapy, lifestyle modifications, and family cascade screening.
يتم الكشف عن الطفرات الممرضة في جين KCNE2 المسؤول عن متلازمة كيو تي الطويلة النوع 6 باستخدام تقنية التسلسل الجيني المتقدم (NGS) لتقديم تشخيص جزيئي دقيق يوجه العلاج الوقائي بمحصرات بيتا وفحص الأقارب.
| Feature | Our KCNE2 NGS Test | Closest Alternative (Sanger Sequencing / Panel) |
|---|---|---|
| Gene Coverage | Complete KCNE2 coding & flanking intronic regions | Often limited to hotspot exons; may miss deep intronic variants |
| Methodology | NGS (Illumina NovaSeq) with ≥100× mean depth | Sanger sequencing of selected exons; lower throughput |
| Turnaround Time | 3‑4 weeks | 4‑6 weeks (samples often batched) |
| Variant Classification | ACMG‑AMP 2026 criteria with in‑house cardiogeneticist review | May lack dedicated cardiac variant interpretation |
| Sample | Blood, extracted DNA, or one drop blood on FTA card | Often requires venous blood only |
Physician Insight & Safety Protocol
Dr. PRABHAKAR REDDY, DHA License 61713011 (Consultant Cardiologist): A positive KCNE2 mutation alone does not diagnose Long QT syndrome; it must be correlated with a thorough clinical evaluation, family history, and 12‑lead ECG. Early detection empowers families to adopt life‑saving measures such as beta‑blocker therapy and avoidance of QT‑prolonging drugs. I strongly recommend non‑directive genetic counselling to fully understand inheritance risks and reproductive options.
Safety Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Inability to provide informed consent; severe acute illness precluding blood draw; pregnancy requires additional pre‑ counselling.
- Emergency Red Flags (seek immediate care): Unexplained fainting (syncope), seizure‑like episodes, palpitations with dizziness, family history of sudden cardiac death under 40, or a known prolonged QT interval on ECG.
Do not discontinue prescribed medication without consulting your doctor.
Patient FAQ & Clinical Guidance
1. What is the KCNE2 gene and why is it tested for Long QT syndrome?
KCNE2 gene mutations impair the heart’s electrical resetting mechanism, predisposing carriers to life‑threatening arrhythmias triggered by exercise or stress. تؤدي طفرات جين KCNE2 إلى اضطراب عودة الاستقطاب القلبي مما يزيد خطورة اضطرابات النظم البطينية الخطيرة.
2. Why is Next‑Generation Sequencing (NGS) used instead of older methods?
NGS provides comprehensive analysis of all coding regions and splice sites, ensuring detection of rare and novel variants missed by traditional single‑exon testing. تقنية التسلسل الجيني الشامل تُحلل كامل الجين مما يرفع حساسية الكشف عن الطفرات النادرة والمتغيرات الجديدة.
3. How does the home collection service work in the UAE?
Yes, our DHA‑licensed phlebotomists perform hospital‑grade blood collection at your home, with strict cold‑chain handling for DNA stability between 8 AM‑11 PM. نعم، يصل إليك أخصائي سحب مرخص من هيئة الصحة بسيارة مزودة بسلسلة تبريد لجمع العينة بأمان خلال ساعات العمل الممتدة.
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
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