Test Price
2,800 AED✅ Home Collection Available
KCNE2 Gene Long QT Syndrome Type 6 Genetic Test in UAE | 2800 AED
Executive Summary & Core Metrics
Executive Summary
Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO 9001:2015 Certified NGS processing, directly aligned with current ACMG/AMP guidelines.
Premium Logistics: VIP Mobile Phlebotomy & Temperature-Controlled Cold-Chain Home Collection (Available daily from 8 AM to 11 PM) with ISO‑Certified transport.
Clinical Guidance: Post‑test telephonic interpretative session with a DHA‑licensed medical geneticist to explain results and action plans.
Insurance: Direct billing verification via WhatsApp at +971 54 548 8731 – most UAE insurers accepted.
Test Overview & Methodology
This advanced Next‑Generation Sequencing (NGS) test screens all coding exons, splice junctions, and known deep intronic regions of the KCNE2 gene to detect pathogenic variants responsible for Long QT syndrome type 6. It delivers a definitive molecular diagnosis that guides prophylactic beta‑blocker therapy, lifestyle modifications, and family cascade screening.
| Feature | Our KCNE2 NGS Test | Closest Alternative (Sanger Sequencing / Panel) |
|---|---|---|
| Gene Coverage | Complete KCNE2 coding & flanking intronic regions | Often limited to hotspot exons; may miss deep intronic variants |
| Methodology | NGS (Illumina NovaSeq) with ≥100× mean depth | Sanger sequencing of selected exons; lower throughput |
| Turnaround Time | 3‑4 weeks | 4‑6 weeks (samples often batched) |
| Variant Classification | ACMG‑AMP criteria with in‑house cardiogeneticist review | May lack dedicated cardiac variant interpretation |
| Sample | Blood, extracted DNA, or one drop blood on FTA card | Often requires venous blood only |
Physician Insight & Safety Protocols
Lina Osama Zaki Quteineh | Consultant Medical Genetics | DHA Registration ID: 9294403: A positive KCNE2 mutation alone does not diagnose Long QT syndrome; it must be correlated with a thorough clinical evaluation, family history, and 12‑lead ECG. Early detection empowers families to adopt life‑saving measures such as beta‑blocker therapy and avoidance of QT‑prolonging drugs. I strongly recommend non‑directive genetic counselling to fully understand inheritance risks and reproductive options.
Advisory Precautions
Do not discontinue prescribed medication without consulting your doctor. If you experience syncope, palpitations, or seizures, seek immediate medical attention. Always inform your physician about any new symptoms during the testing period.
Exclusion Criteria & Emergency Red Flags
- Exclusion Criteria: Inability to provide informed consent; severe acute illness precluding blood draw; pregnancy requires additional pre‑counselling.
- Emergency Red Flags (seek immediate care): Unexplained fainting (syncope), seizure‑like episodes, palpitations with dizziness, family history of sudden cardiac death under 40, or a known prolonged QT interval on ECG.
Patient FAQ & Clinical Guidance
1. What is the KCNE2 gene and why is it tested for Long QT syndrome?
KCNE2 gene mutations impair the heart’s electrical resetting mechanism, predisposing carriers to life‑threatening arrhythmias triggered by exercise or stress. Testing identifies at‑risk individuals for early intervention.
2. Why is Next‑Generation Sequencing (NGS) used instead of older methods?
NGS provides comprehensive analysis of all coding regions and splice sites, ensuring detection of rare and novel variants missed by traditional single‑exon testing. This increases diagnostic sensitivity and accuracy.
3. How does the home collection service work in the UAE?
Our DHA‑licensed phlebotomists perform hospital‑grade blood collection at your home, with strict cold‑chain handling for DNA stability between 8 AM‑11 PM. Samples are transported directly to our ISO‑certified laboratory.
UAE Regulatory & Data Privacy Adherence
Compliance & Certification
This laboratory is fully compliant with Federal Decree-Law No. 45 of 2021 on Personal Data Protection (PDPL) and Federal Law No. 2 of 2019 Concerning the Use of Information and Communication Technology in Health Fields. All genetic data is encrypted, access‑controlled, and handled under strict confidentiality agreements. Our ISO 9001:2015 certification (Cert No: INT/EGQ/2509DA/3139) ensures quality management in every step of the testing process.
Clinical & Logistical Metadata
| Test Name | KCNE2 Gene Long QT Syndrome Type 6 Genetic Test |
| Price (AED) | 2,800 AED |
| Turnaround Time | 3–4 weeks |
| Sample Type / Matrix | Peripheral whole blood, extracted DNA, or dried blood spot (FTA card) |
| Methodology Used | Next-Generation Sequencing (NGS) on Illumina NovaSeq, ≥100× mean depth |
| ICD-10-CM Code | I45.81 |
| LOINC Code | 91806-5 |
| DHA Facility License & Laboratory Address | DHA License No. 1143 | Premises 105, Floor 1, Building 33, Dubai Healthcare City, Dubai, UAE | Corporate Lab: DNA Labs UAE |
دعم ثنائي اللغة متاح
التحقق من التغطية التأمينية
Check Insurance Coverage Instantly
Stop the guesswork. Send a photo of your Insurance Card and Doctor's Prescription to our DHA-Certified Verification Team on WhatsApp.
توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
ISO Accredited
HIPAA
All reports reviewed by DHA-Certified physicians