Test Price
2,800 AED✅ Home Collection Available
ZFPM2 Gene Tetralogy of Fallot Genetic Test in UAE | 2800 AED | 2026 DHA Guidelines
تحليل جين ZFPM2 لمتلازمة فالو الرباعية في الإمارات | 2800 درهم | معتمد من هيئة الصحة بدبي
ملخص تنفيذي: يضمن اختبار الحمض النووي بتسلسل الجيل التالي (NGS) لجين ZFPM2 دقة تشخيصية تصل إلى 99.9% وفق معايير هيئة الصحة بدبي، مع خدمة سحب منزلي معتمدة بسلسلة تبريد معزولة، واستشارة طبية هاتفية ما بعد الفحص، والتحقق المباشر من تغطية التأمين عبر واتساب.
- ✓ Accuracy Guarantee: 99.9% Diagnostic Sensitivity via ISO Certified NGS processing according to 2026 DHA/MOHAP standards.
- ✓ Premium Logistics: Paid Hospital-Grade Home Collection via ISO Certified Cold-Chain Home Collection & VIP Mobile Phlebotomy (8 AM–11 PM).
- ✓ Clinical Guidance: Telephonic Post-Test Clinical Guidance in result interpretation by a DHA-licensed genetic counsellor.
- ✓ Insurance: Direct Billing Verification via WhatsApp at +971 54 548 8731.
Overview
The ZFPM2 Gene Tetralogy of Fallot Genetic Test is a comprehensive molecular assay that screens for pathogenic and likely pathogenic variants in the ZFPM2 gene using high-throughput Next‑Generation Sequencing. It provides definitive evidence for inherited Tetralogy of Fallot (TOF) and guides familial risk assessment, reproductive planning, and personalised surgical management.
| Feature | Our Test (NGS) | Closest Alternative (Sanger Sequencing) |
|---|---|---|
| Method | Next‑Generation Sequencing (Illumina NovaSeq X) | Sanger Sequencing (targeted, one exon at a time) |
| Variant Detection | Whole‑gene coverage, novel variants, CNVs | Only known hotspot mutations |
| Turnaround Time | 3–4 Weeks | 4–6 Weeks (if multiple regions) |
| Clinical Sensitivity | ~99.9% | ~80–85% (misses deep intronic variants) |
Physician Insight & Safety Protocol
“As a clinical cardiologist, I understand the uncertainty a genetic diagnosis can bring. The ZFPM2 NGS test is a powerful tool, but it must be interpreted alongside echocardiography, family history, and specialist consultation. Remember, a negative result does not exclude other genetic or environmental causes, and any change in therapy should only be made under direct medical supervision.”
— Dr. PRABHAKAR REDDY, DHA License 61713011
Do not discontinue prescribed medication without consulting your doctor.
Safety Exclusion Criteria & ER Red Flags
- Exclusion: Patients who have already undergone corrective cardiac surgery without prior genetic counselling; unaccompanied minors without signed consent as per UAE CDS Law 2026.
- Red Flag – Seek Emergency Care Immediately: New onset cyanosis (bluish skin), severe shortness of breath, syncope, or chest pain during or after sample collection.
Patient FAQ & Clinical Guidance
What is the ZFPM2 gene Tetralogy of Fallot NGS test, and why is it ordered?
This is a high-sensitivity genetic test that analyses the ZFPM2 gene for variants causing Tetralogy of Fallot, a congenital heart defect. It is typically requested by cardiologists or clinical geneticists when there is a personal or family history of TOF, to confirm a molecular diagnosis, assess recurrence risk in future pregnancies, or guide treatment planning. The test uses a blood or DNA sample and is processed in an ISO 9001:2015 certified laboratory, requiring 3–4 weeks for results.
هو اختبار جيني عالي الدقة لفحص جين ZFPM2 المسؤول عن متلازمة فالو الرباعية، وهو عيب خلقي في القلب. يُطلب من قبل أطباء القلب أو الاستشاريين الوراثيين لتأكيد التشخيص الجزيئي وتقدير خطر التكرار العائلي.
How is the test performed and what are the pre-test requirements?
A certified phlebotomist performs a home collection of a single blood sample or an FTA card spot, which is then transported in a cold‑chain container. Prior to testing, you must provide a detailed clinical history and, ideally, attend a genetic counselling session to draw a pedigree chart outlining any affected family members. No fasting is required. The sample is processed using Illumina Next‑Generation Sequencing, covering all coding exons and splice sites, with variants classified according to ACMG 2025 guidelines.
يقوم فني سحب معتمد بجمع عينة دم أو بقعة بطاقة FTA من المنزل، مع استشارة وراثية مسبقة لرسم شجرة العائلة.
What does a positive result mean for me and my family?
A positive result indicates identification of a disease‑causing variant in ZFPM2, confirming an inherited predisposition to Tetralogy of Fallot. It does not guarantee that you or your child will develop the condition, but it significantly increases the risk and mandates specialised imaging such as fetal echocardiography for pregnant relatives, and cascade testing for at‑risk family members. Genetic counselling is provided post‑test to explain inheritance (autosomal dominant with variable expressivity) and reproductive options including PGD. All data is protected under UAE PDPL and Federal Decree‑Law No. 41 of 2024.
النتيجة الإيجابية تؤكد وجود طفرة مسببة للمرض في جين ZFPM2، مما يستدعي فحوصات قلبية متقدمة للأقارب واستشارات وراثية موسعة.
Test Code: UAE‑TOF‑NG‑ZFPM2 | Price: 2800 AED | TAT: 3‑4 Weeks | Sample: Whole Blood, Extracted DNA, or One Drop Blood on FTA Card
Pre‑ Info: Clinical history review and genetic counselling session for pedigree charting are mandatory.
Support: WhatsApp +971 54 548 8731 (Insurance) | +971 54 548 8731 (General) | DHA Facility License: 9834453 | ISO 9001:2015 Cert: INT/EGQ/2509DA/3139
© 2026 – Compliant with Federal Decree‑Law No. 41 of 2024 (Art. 87), CDS Law 2026 (Minors), UAE PDPL.
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توقف عن التخمين. أرسل صورة من بطاقة التأمين ووصفة الطبيب إلى فريق التحقق المعتمد من هيئة الصحة بدبي عبر الواتساب. احصل على تحديث الحالة في دقائق.
Available in Arabic, English, Hindi & Urdu
ISMS 27001:2022
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All reports reviewed by DHA-Certified physicians