TACROLIMUS GENOTYPING CYP3A5 Test
Introduction
The Tacrolimus Genotyping (CYP3A5) test is a genetic test offered by DNA Labs UAE. This test determines an individual’s CYP3A5 genotype, which is crucial for the metabolism of tacrolimus, a medication commonly used in organ transplant patients to prevent rejection.
Test Details
The Tacrolimus Genotyping (CYP3A5) test helps determine an individual’s ability to metabolize tacrolimus, which can vary depending on their CYP3A5 genotype. There are two common genotypes: CYP3A5 expressers (CYP3A5*1) and non-expressers (CYP3A5*3).
CYP3A5 expressers have higher enzyme activity and may require higher doses of tacrolimus for therapeutic levels, while non-expressers have lower enzyme activity and may require lower doses. By identifying an individual’s CYP3A5 genotype, healthcare providers can personalize the dosage of tacrolimus to optimize therapeutic levels and minimize the risk of adverse effects.
This test is particularly useful in organ transplant patients who require long-term tacrolimus therapy to ensure proper drug dosing and efficacy.
Test Components and Price
The TACROLIMUS GENOTYPING CYP3A5 Test is priced at 1220.0 AED. The sample condition required is 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube. It should be shipped refrigerated and should not be frozen. The report delivery is on Sample Mon / Thu by 11 am and the report will be delivered on Wed / Sat.
Method and Test Type
The Tacrolimus Genotyping (CYP3A5) test is performed using the Real Time PCR method. It falls under the category of therapeutic drug monitoring.
Doctor and Test Department
The TACROLIMUS GENOTYPING CYP3A5 Test is recommended by Nephrologists and Transplant Surgeons. It is conducted in the Molecular Diagnostics department of DNA Labs UAE.
Pre Test Information
No special preparation is required for the TACROLIMUS GENOTYPING CYP3A5 Test.
Conclusion
The TACROLIMUS GENOTYPING CYP3A5 Test offered by DNA Labs UAE is a crucial genetic test for organ transplant patients on long-term tacrolimus therapy. By determining an individual’s CYP3A5 genotype, healthcare providers can personalize the dosage of tacrolimus to optimize therapeutic levels and minimize the risk of adverse effects. The test cost is 1220.0 AED, and the sample required is 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube. It is performed using the Real Time PCR method in the Molecular Diagnostics department. Nephrologists and Transplant Surgeons recommend this test to ensure proper drug dosing and efficacy.
| Test Name | TACROLIMUS GENOTYPING CYP3A5 Test |
|---|---|
| Components | |
| Price | 1220.0 AED |
| Sample Condition | 3 ml (2 ml min.) whole blood in 1 Lavender top (EDTA) tube. Ship refrigerated. DO NOT FREEZE. |
| Report Delivery | Sample Mon / Thu by 11 am; Report Wed / Sat |
| Method | Real Time PCR |
| Test type | Therapeutic drug monitoring |
| Doctor | Nephrologist, Transplant surgeon |
| Test Department: | MOLECULAR DIAGNOSTICS |
| Pre Test Information | No special preparation required |
| Test Details | The Tacrolimus Genotyping (CYP3A5) test is a genetic test that determines an individual’s CYP3A5 genotype. The CYP3A5 gene encodes an enzyme that is responsible for the metabolism of tacrolimus, a medication commonly used in organ transplant patients to prevent rejection. The test helps determine an individual’s ability to metabolize tacrolimus, which can vary depending on their CYP3A5 genotype. There are two common genotypes: CYP3A5 expressers (CYP3A5*1) and non-expressers (CYP3A5*3). CYP3A5 expressers have higher enzyme activity and may require higher doses of tacrolimus for therapeutic levels, while non-expressers have lower enzyme activity and may require lower doses. By identifying an individual’s CYP3A5 genotype, healthcare providers can personalize the dosage of tacrolimus to optimize therapeutic levels and minimize the risk of adverse effects. This test is particularly useful in organ transplant patients who require long-term tacrolimus therapy to ensure proper drug dosing and efficacy. |
